Biomechanical Deviations During Level Walking Associated With Knee Osteoarthritis: A Systematic Review and Meta‐Analysis

Kathryn Mills; Michael A. Hunt; Reed Ferber

doi:10.1002/acr.22015

journal article Sep 24, 2013

Biomechanical Deviations During Level Walking Associated With Knee Osteoarthritis: A Systematic Review and Meta‐Analysis

Kathryn Mills Michael A. Hunt

Reed Ferber

Arthritis Care & Research Vol. 65 No. 10 pp. 1643-1665 · Wiley

View at Publisher Save 10.1002/acr.22015

Abstract

ObjectiveTo identify which gait deviations are consistently associated with knee osteoarthritis (KOA) and how these are influenced by disease severity, the involved compartment, and sex.MethodsFive electronic databases and reference lists of publications were searched. Cross‐sectional, observational studies comparing temporospatial variables, joint kinematics, and joint moments between individuals with KOA and healthy controls or between KOA subgroups were considered for review. Only publications scoring ≥50% on a modified methodology quality index were included. Because of the number of gait deviations examined, only biomechanical variables reported by ≥4 publications were further analyzed. Where possible, a meta‐analysis was performed using effect sizes (ES) calculated from discrete variables.ResultsIn total, 41 publications examining 20 variables were included. The majority of consistent gait deviations associated with KOA were exhibited by those with severe disease in the temporospatial domain. Individuals with severe KOA exhibited greater stride duration than controls (ES 1.35 [95% confidence interval (95% CI) 1.03, 1.67]) and a decrease in cadence (ES −0.75 [95% CI −1.12, −0.39]) compared with controls. The evidence for kinematic and joint moment change was primarily limited or conflicting. There was a lack of evidence for alterations in the external knee adduction moment.ConclusionIndividuals with KOA exhibit a range of gait deviations compared with controls. Despite its common usage in KOA gait studies, we did not find consistent evidence that knee adduction moment differs between those with and without KOA or between disease severity levels. Further research examining the reasons for a lack of difference in many gait variables in those with knee OA is needed.

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References

62

[1]

10.1016/j.joca.2010.10.020

[2]

10.1016/j.knee.2011.07.003

[3]

10.1016/j.clinbiomech.2009.01.005

[4]

10.1080/08952840903054856

[5]

10.1002/jor.20194

[6]

10.2522/ptj.20060137

[7]

10.1016/0021-9290(90)90358-a

[8]

10.1016/j.jsams.2009.03.004

[9]

10.1136/jech.52.6.377

[10]

HopkinsWG. A new view of statistics. URL:www.sportsciorg/resource/stat2000.

[11]

10.1016/s0140-6736(10)61160-9

[12]

10.1249/mss.0b013e31818cb278

[13]

10.1186/1471-2288-5-13

[14]

10.1002/sim.1186

[15]

10.1097/01.brs.0000065484.95996.af

[16]

10.1002/jor.20496

[17]

10.1097/01.phm.0000056987.33630.56

[18]

10.1016/j.medengphy.2008.02.006

[19]

10.1002/acr.20248

[20]

10.1016/j.joca.2004.05.005

[21]

10.2522/ptj.20100324

[22]

10.1016/j.clinbiomech.2009.08.005

[23]

10.1016/j.gaitpost.2011.09.020

[24]

10.1016/s0966-6362(02)00009-7

[25]

10.1016/j.joca.2007.11.012

[26]

10.1016/j.clinbiomech.2009.02.005

[27]

10.1016/j.clinbiomech.2010.11.018

[28]

10.1016/j.jelekin.2008.12.003

[29]

10.1016/j.gaitpost.2005.06.003

[30]

10.1016/j.jelekin.2005.07.014

[31]

10.1007/s00167-005-0005-6

[32]

10.1016/j.gaitpost.2006.01.007

[33]

10.1002/art.21262

[34]

10.1016/j.jbiomech.2006.08.010

[35]

10.1016/j.clinbiomech.2010.07.012

[36]

10.1016/j.clinbiomech.2006.11.006

[37]

10.1016/j.clinbiomech.2009.02.001

[38]

10.3109/17453670209178029

[39]

10.1002/art.22889

[40]

10.1016/s0736-0266(01)00081-x

[41]

10.1053/joca.2002.0797

[42]

10.1016/j.apmr.2011.11.029

[43]

10.1016/j.clinbiomech.2011.12.007

[44]

10.1016/j.gaitpost.2010.11.006

[45]

10.1016/s0021-9290(01)00036-7

[46]

Sahai A "Relationship between frontal and sagittal plane knee kinetics during walking in subjects with and without knee pain" Clin Kinesiol (2003)

[47]

10.1016/j.apmr.2004.05.015

[48]

Hodges PW "Rate of cartilage loss in medial knee osteoarthritis is faster in patients with increased duration of cocontraction of medial knee muscles" J Orthop Sports Phys Ther (2012)

[49]

10.1002/jor.1100090114

[50]

10.1016/s1063-4584(11)60206-9

Showing 50 of 62 references

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189

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References

Details

Published: Sep 24, 2013
Vol/Issue: 65(10)
Pages: 1643-1665
License: View

Authors

K

Kathryn Mills

University of Calgary Calgary, Alberta Canada

M

Michael A. Hunt

University of British Columbia Vancouver, British Columbia Canada

R

Reed Ferber

University of Calgary Calgary, Alberta Canada

Cite This Article

Kathryn Mills, Michael A. Hunt, Reed Ferber (2013). Biomechanical Deviations During Level Walking Associated With Knee Osteoarthritis: A Systematic Review and Meta‐Analysis. Arthritis Care & Research, 65(10), 1643-1665. https://doi.org/10.1002/acr.22015

Biomechanical Deviations During Level Walking Associated With Knee Osteoarthritis: A Systematic Review and Meta‐Analysis

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