Biosensing with Fluorescent Carbon Nanotubes

Julia Ackermann; Justus T. Metternich; Svenja Herbertz; Sebastian Kruss

doi:10.1002/anie.202112372

journal article Open Access Mar 01, 2022

Biosensing with Fluorescent Carbon Nanotubes

Julia Ackermann

Justus T. Metternich

Svenja Herbertz

Sebastian Kruss

Angewandte Chemie International Edition Vol. 61 No. 18 · Wiley

View at Publisher Save 10.1002/anie.202112372

Abstract

AbstractBiosensors are powerful tools for modern basic research and biomedical diagnostics. Their development requires substantial input from the chemical sciences. Sensors or probes with an optical readout, such as fluorescence, offer rapid, minimally invasive sensing of analytes with high spatial and temporal resolution. The near‐infrared (NIR) region is beneficial because of the reduced background and scattering of biological samples (tissue transparency window) in this range. In this context, single‐walled carbon nanotubes (SWCNTs) have emerged as versatile NIR fluorescent building blocks for biosensors. Here, we provide an overview of advances in SWCNT‐based NIR fluorescent molecular sensors. We focus on chemical design strategies for diverse analytes and summarize insights into the photophysics and molecular recognition. Furthermore, different application areas are discussed—from chemical imaging of cellular systems and diagnostics to in vivo applications and perspectives for the future.

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Metrics

240

Citations

277

References

Details

Published: Mar 01, 2022
Vol/Issue: 61(18)
License: View

Authors

J

Julia Ackermann

Biomedical Nanosensors Fraunhofer Institute for Microelectronic Circuits and Systems Finkenstrasse 61 47057 Duisburg Germany; Department EBS University Duisburg-Essen Bismarckstrasse 81 47057 Duisburg Germany

J

Justus T. Metternich

Physical Chemistry Ruhr-University Bochum Universitätsstrasse 150 44801 Bochum Germany; Biomedical Nanosensors Fraunhofer Institute for Microelectronic Circuits and Systems Finkenstrasse 61 47057 Duisburg Germany

S

Svenja Herbertz

Biomedical Nanosensors Fraunhofer Institute for Microelectronic Circuits and Systems Finkenstrasse 61 47057 Duisburg Germany

S

Sebastian Kruss

Physical Chemistry Ruhr-University Bochum Universitätsstrasse 150 44801 Bochum Germany; Biomedical Nanosensors Fraunhofer Institute for Microelectronic Circuits and Systems Finkenstrasse 61 47057 Duisburg Germany

Funding

Deutsche Forschungsgemeinschaft Award: EXC 2033 - 390677874 - RESOLV

Fraunhofer-Gesellschaft Award: Attract 038-610097

Cite This Article

Julia Ackermann, Justus T. Metternich, Svenja Herbertz, et al. (2022). Biosensing with Fluorescent Carbon Nanotubes. Angewandte Chemie International Edition, 61(18). https://doi.org/10.1002/anie.202112372

Biosensing with Fluorescent Carbon Nanotubes

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