Pre‐Clinical Testing of Microwave Radiometer and a Pilot Study on the Screening Inflammation of Knee Joints

Vidyalakshmi M. Ravi; Amit K. Sharma; Kavitha Arunachalam

doi:10.1002/bem.22203

journal article Jul 16, 2019

Pre‐Clinical Testing of Microwave Radiometer and a Pilot Study on the Screening Inflammation of Knee Joints

Vidyalakshmi M. Ravi Amit K. Sharma Kavitha Arunachalam

Bioelectromagnetics Vol. 40 No. 6 pp. 402-411 · Wiley

View at Publisher Save 10.1002/bem.22203

Abstract

This article presents the pre‐clinical evaluation of our custom‐built, single‐band microwave radiometer centered at 1.3 GHz for deep tissue thermometry, and a pilot study on volunteers for passive detection of inflammation in knee joints. The electromagnetic (EM) compatibility of the battery‐operated radiometer for clinical use was assessed as per International Special Committee on Radio Interference (CISPR) 22 standard. The ability to detect inflammation in knee joints was assessed using a substrate integrated waveguide antenna connected to the radiometer. EM compatibility tests carried out in the laboratory indicated device immunity to intentional radiated interference up to −20 dBm injected power in the global system for mobile communication frequency band, and pre‐compliance to CISPR 22 standard. Radiometer temperature measurements recorded at the lateral and medial aspects of both knees of 41 volunteers indicated mean temperature greater than 33°C for the diseased sites compared with the mean temperature of 28°C measured for the healthy sites. One‐way analysis of variance statistics indicated significantly (P < 0.005) higher radiometer temperature at the diseased sites unlike the healthy sites. Thus, the EM pre‐compliance of the device and the potential to measure deep tissue inflammation were demonstrated. Bioelectromagnetics. 2019;40:402–411. © 2019 Bioelectromagnetics Society.

Topics

No keywords indexed for this article. Browse by subject →

References

32

[1]

10.1109/tbme.2011.2107515

[2]

10.1136/ard.2007.081554

[3]

10.1109/jsen.2011.2113332

[4]

10.1038/nrrheum.2010.173

[5]

10.1136/ard.2004.035246

[6]

10.1038/nrrheum.2009.227

[7]

10.3109/02656736.2015.1068957

[8]

Clayton PR (2017)

[9]

10.2967/jnumed.117.204339

[10]

10.1186/ar553

[11]

10.2217/ijr.10.105

[12]

10.1049/el:20070577

[13]

10.1007/s10067-018-4108-0

[14]

10.1109/titb.2012.2187301

[15]

10.3346/jkms.2014.29.2.204

[16]

10.1109/tbme.2011.2172441

[17]

10.1088/0957-0233/18/7/018

[18]

10.1088/0967-3334/36/2/273

[19]

10.1109/jsen.2018.2791443

[20]

10.1109/22.884206

[21]

10.1109/mmm.2011.942702

[22]

10.1016/j.berh.2004.08.006

[23]

10.1109/mcom.2014.6917412

[24]

10.1049/iet-map.2017.0340

[25]

10.1109/tbme.2014.2317484

[26]

10.1136/ard.2004.030387

[27]

10.1016/j.jpurol.2011.05.005

[28]

10.1186/ar2360

[29]

10.15274/nrj-2014-10001

[30]

Interobserver agreement in ultrasonography of the finger and toe joints in rheumatoid arthritis

Marcin Szkudlarek, Michel Court‐Payen, Søren Jacobsen et al.

Arthritis & Rheumatism 10.1002/art.10877

[31]

10.1016/j.jacc.2012.01.033

[32]

10.1371/journal.pone.0064606

Metrics

16

Citations

32

References

Details

Published: Jul 16, 2019
Vol/Issue: 40(6)
Pages: 402-411
License: View

Authors

V

Vidyalakshmi M. Ravi

Department of Engineering Design Indian Institute of Technology Madras Chennai India

A

Amit K. Sharma

Institute Hospital, Indian Institute of Technology Madras Chennai India

K

Kavitha Arunachalam

Department of Engineering Design Indian Institute of Technology Madras Chennai India

Cite This Article

Vidyalakshmi M. Ravi, Amit K. Sharma, Kavitha Arunachalam (2019). Pre‐Clinical Testing of Microwave Radiometer and a Pilot Study on the Screening Inflammation of Knee Joints. Bioelectromagnetics, 40(6), 402-411. https://doi.org/10.1002/bem.22203

Pre‐Clinical Testing of Microwave Radiometer and a Pilot Study on the Screening Inflammation of Knee Joints

You May Also Like