The coordination of cell growth and division — intentional or Incidental?

John J. Tyson

doi:10.1002/bies.950020208

journal article Feb 01, 1985

The coordination of cell growth and division — intentional or Incidental?

John J. Tyson

BioEssays Vol. 2 No. 2 pp. 72-77 · Wiley

View at Publisher Save 10.1002/bies.950020208

Abstract

AbstractDuring balanced growth of cells in culture all extensive properties of the culture — e.g. cell number, total mass, total DNA content — increase exponentially at the same specific growth rate. Therefore, in some average sense, each component of a cell must double between birth and division. For DNA there exists an elaborate mechanism to ensure precise replication of the genetic material and accurate partitioning of identical copies of the genome to the two daughter cells. Do cells possess another mechanism that intentionally relates the timing of cell division to overall increase in cell size, or is the coordination of growth and division an incidental consequence of size‐independent rules for progress through the cell cycle?.

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38

References

Details

Published: Feb 01, 1985
Vol/Issue: 2(2)
Pages: 72-77
License: View

Authors

J

John J. Tyson

Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg Virginia 24061; and

Cite This Article

John J. Tyson (1985). The coordination of cell growth and division — intentional or Incidental?. BioEssays, 2(2), 72-77. https://doi.org/10.1002/bies.950020208

The coordination of cell growth and division — intentional or Incidental?

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