Estimation of diffusion coefficients of proteins

M. E. Young; P. A. Carroad; R. L. Bell

doi:10.1002/bit.260220504

journal article May 01, 1980

Estimation of diffusion coefficients of proteins

M. E. Young P. A. Carroad R. L. Bell

Biotechnology and Bioengineering Vol. 22 No. 5 pp. 947-955 · Wiley

View at Publisher Save 10.1002/bit.260220504

Abstract

AbstractA correlation for estimating the diffusion coefficients of protein molecules is presented. The correlation is based upon literature values of the protein diffusion coefficients and molal volumes for 143 proteins. The correlation can be used for the estimation of diffusion coefficients using only molecular weight. Accuracy is such that a linear regression on 301 proteins showed 75% of the diffusion coefficients estimated fell within 20% of the experimental values. The relationship between this correlation, the Stokes–Einstein equation, and the Wilke–Chang correlation is discussed.

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Metrics

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Citations

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References

Details

Published: May 01, 1980
Vol/Issue: 22(5)
Pages: 947-955
License: View

Authors

Department of Horticulture, Purdue University, West Lafayette, IN 47907

Cite This Article

M. E. Young, P. A. Carroad, R. L. Bell (1980). Estimation of diffusion coefficients of proteins. Biotechnology and Bioengineering, 22(5), 947-955. https://doi.org/10.1002/bit.260220504

Estimation of diffusion coefficients of proteins

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