Intravascular lithotripsy in heavily calcified chronic total occlusion: procedural and one‐year clinical outcomes

Federico Oliveri; Martijn J. H. Van Oort; Ibtihal Al Amri; Brian O. Bingen; Bimmer E. Claessen; Aukelien C. Dimitriu‐Leen; Joelle Kefer; Hany Girgis; Tessel Vossenberg; Frank Van Der Kley; J. Wouter Jukema; Jose M. Montero‐Cabezas

doi:10.1002/ccd.31207

journal article Open Access Aug 29, 2024

Intravascular lithotripsy in heavily calcified chronic total occlusion: procedural and one‐year clinical outcomes

Federico Oliveri

Martijn J. H. Van Oort

Ibtihal Al Amri Brian O. Bingen

Bimmer E. Claessen

Aukelien C. Dimitriu‐Leen Joelle Kefer Hany Girgis Tessel Vossenberg Frank Van Der Kley

J. Wouter Jukema

Jose M. Montero‐Cabezas

Catheterization and Cardiovascular Interventions Vol. 104 No. 4 pp. 655-663 · Wiley

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Abstract

AbstractBackgroundCalcification within chronic total occlusions (CTO) is strongly associated with worse outcomes. Despite the excellent success and safety of intravascular lithotripsy (IVL) in heavily calcified lesions, evidence in CTO remains scarce.AimThis study aimed to evaluate the procedural and long‐term clinical outcomes of IVL in heavily calcified CTO.MethodsPatients who underwent IVL between 2019 and 2024 from an ongoing prospective multicenter registry were eligible for inclusion. Patients were therefore classified in CTO and non‐CTO groups. The efficacy and safety endpoints of CTO percutaneous coronary interventions were defined according to the CTO‐ARC consensus. In‐hospital major adverse cardiovascular events (MACE) included cardiac death, nonfatal myocardial infarction and target lesion revascularization (TVR).ResultsA total of 404 patients underwent IVL, of which the treated lesion was a CTO in 33 (8.2%). The mean J‐CTO score was 2.3 ± 1.1. Device success showed no significant difference between CTO and non‐CTO groups (100% vs 98.4%; p = 0.35). Comparable technical success with residual stenosis <30% was observed in both groups (90.1% in CTO vs 89.2% in non‐CTO, p = 0.83). The incidence of MACE was similar across groups during hospital stays (CTO 6.0% vs. non‐CTO 1.9%, p = 0.12), at 30‐day (CTO 9.1% vs. non‐CTO 3.0%, p = 0.07), and at 12‐month follow‐up (CTO 9.1% vs. non‐CTO 7.3%, p = 0.70).ConclusionIVL provides high procedural success and consistent clinical outcomes in both CTO and non‐CTO cases, reinforcing its role in managing heavily calcified coronary lesions.

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Details

Published: Aug 29, 2024
Vol/Issue: 104(4)
Pages: 655-663
License: View

Authors

F

Federico Oliveri

Department of Cardiology Leiden University Medical Center Leiden The Netherlands

M

Martijn J. H. Van Oort

Department of Cardiology Leiden University Medical Center Leiden The Netherlands

I

Ibtihal Al Amri

Department of Cardiology Leiden University Medical Center Leiden The Netherlands

B

Brian O. Bingen

Department of Cardiology Leiden University Medical Center Leiden The Netherlands

B

Bimmer E. Claessen

Department of Cardiology Amsterdam University Medical Center The Netherlands

A

Aukelien C. Dimitriu‐Leen

Department of Cardiology Radboud University Medical Center The Netherlands

J

Joelle Kefer

Department of Cardiology Saint‐Luc Bruxelles Belgium

H

Hany Girgis

Department of Cardiology Jeroen Bosch Ziekenhuis Den‐Bosch The Netherlands

T

Tessel Vossenberg

Department of Cardiology Medisch Centrum Leeuwarden The Netherlands

F

Frank Van Der Kley

Department of Cardiology Leiden University Medical Center Leiden The Netherlands

J

J. Wouter Jukema

Department of Cardiology Leiden University Medical Center Leiden The Netherlands; Netherlands Heart Institute Utrecht The Netherlands

J

Jose M. Montero‐Cabezas

Department of Cardiology Leiden University Medical Center Leiden The Netherlands

Cite This Article

Federico Oliveri, Martijn J. H. Van Oort, Ibtihal Al Amri, et al. (2024). Intravascular lithotripsy in heavily calcified chronic total occlusion: procedural and one‐year clinical outcomes. Catheterization and Cardiovascular Interventions, 104(4), 655-663. https://doi.org/10.1002/ccd.31207

Intravascular lithotripsy in heavily calcified chronic total occlusion: procedural and one‐year clinical outcomes

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