journal article Aug 22, 2025

Electrochemical C–H Functionalization for the Construction of C–O Bonds: A Comprehensive Review

Chinese Journal of Chemistry Vol. 43 No. 23 pp. 3302-3328 · Wiley
View at Publisher Save 10.1002/cjoc.70202
Abstract
Comprehensive Summary



The topic of C–H functionalization and C–O formation is the most important area in organic synthesis. Traditional methods are very limited due to the necessary external oxidants, whereas the rapidly developing electrochemical synthesis uses electrons as internal redox reagents. Consequently, electrochemical C–H functionalization for the construction of C–O bonds has emerged as an active area of research. This review categorizes recent reports on the electrochemical formation of C–O bonds with various C–H sources based on the hybridization (sp
3
, sp
2
) of the carbon atoms involved. Potential readers will gain a more comprehensive understanding of advances in the field through this review.






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Details
Published
Aug 22, 2025
Vol/Issue
43(23)
Pages
3302-3328
License
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Funding
National Natural Science Foundation of China Award: 22101299
Chinese Universities Scientific Fund Award: 2025TC055
Cite This Article
Chen Liu, Renxiu Zhang, Yunge Liu, et al. (2025). Electrochemical C–H Functionalization for the Construction of C–O Bonds: A Comprehensive Review. Chinese Journal of Chemistry, 43(23), 3302-3328. https://doi.org/10.1002/cjoc.70202