Ontogeny of Rat Recognition Memory measured by the novel object recognition task

Maxine L. Reger; David A. Hovda; Christopher C. Giza

doi:10.1002/dev.20402

journal article Sep 08, 2009

Ontogeny of Rat Recognition Memory measured by the novel object recognition task

Maxine L. Reger David A. Hovda Christopher C. Giza

Developmental Psychobiology Vol. 51 No. 8 pp. 672-678 · Wiley

View at Publisher Save 10.1002/dev.20402

Abstract

AbstractDetection of novelty is an essential component of recognition memory, which develops throughout cerebral maturation. To better understand the developmental aspects of this memory system, the novel object recognition task (NOR) was used with the immature rat and ontogenically profiled. It was hypothesized that object recognition would vary across development and be inferior to adult performance. The NOR design was made age‐appropriate by downsizing the testing objects and arena. Weanling (P20–23), juvenile (P29–40), and adult (P50+) rats were tested after 0.25, 1, 24, and 48 hr delays. Weanlings exhibited novel object recognition at 0.25 and 1 hr, while older animals showed a preference for the novel object out to 24 hr. These findings are consistent with previous research performed in humans and monkeys, as well as to studies using the NOR after medial temporal lobe damage in adult rats. © 2009 Wiley Periodicals, Inc. Dev Psychobiol 51: 672–678, 2009

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References

Details

Published: Sep 08, 2009
Vol/Issue: 51(8)
Pages: 672-678
License: View

Authors

University of California, Los Angeles, California

C

Christopher C. Giza

Cite This Article

Maxine L. Reger, David A. Hovda, Christopher C. Giza (2009). Ontogeny of Rat Recognition Memory measured by the novel object recognition task. Developmental Psychobiology, 51(8), 672-678. https://doi.org/10.1002/dev.20402

Ontogeny of Rat Recognition Memory measured by the novel object recognition task

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