Different degree of paternal mtDNA leakage between male and female progeny in interspecific Drosophila crosses

Emmanouil Dokianakis; Emmanuel D. Ladoukakis

doi:10.1002/ece3.1069

journal article Open Access Jun 19, 2014

Different degree of paternal mtDNA leakage between male and female progeny in interspecific Drosophila crosses

Emmanouil Dokianakis Emmanuel D. Ladoukakis

Ecology and Evolution Vol. 4 No. 13 pp. 2633-2641 · Wiley

View at Publisher Save 10.1002/ece3.1069

Abstract

AbstractMaternal transmission of mitochondrial DNA (mtDNA) in animals is thought to prevent the spread of selfish deleterious mtDNA mutations in the population. Various mechanisms have been evolved independently to prevent the entry of sperm mitochondria in the embryo. However, the increasing number of instances of paternal mtDNA leakage suggests that these mechanisms are not very effective. The destruction of sperm mitochondria in mammalian embryos is mediated by nuclear factors. Also, the destruction of paternal mitochondria in intraspecific crosses is more effective than in interspecific ones. These observations have led to the hypothesis that leakage of paternal mtDNA (and consequently mtDNA recombination owing to ensuing heteroplasmy) might be more common in inter‐ than in intraspecific crosses and that it should increase with phylogenetic distance of hybridizing species. We checked paternal leakage in inter‐ and intraspecific crosses in Drosophila and found little evidence for this hypothesis. In addition, we have observed a higher level of leakage among male than among female progeny from the same cross. This is the first report of sex‐specific leakage of paternal mtDNA. It suggests that paternal mtDNA leakage might not be a stochastic result of an error‐prone mechanism, but rather, it may be under complex genetic control.

Topics

No keywords indexed for this article. Browse by subject →

References

51

[1]

Ashburner M. (2004)

[2]

10.1007/s002390010067

[3]

10.1007/s002390010066

[4]

10.1073/pnas.77.10.6032

[5]

10.1073/pnas.92.25.11331

[6]

10.1146/annurev.genet.35.102401.090231

[7]

10.1093/genetics/144.3.1063

[8]

10.1371/journal.pone.0041433

[9]

Dean M. D. "Influence of two Wolbachia strains on population structure of East African Drosophila simulans" Genetics (2003) 10.1093/genetics/165.4.1959

[10]

10.1093/genetics/78.2.737

[11]

10.1017/s0016672312000031

[12]

Gordo I. "The degeneration of asexual haploid populations and the speed of Muller's ratchet" Genetics (2000) 10.1093/genetics/154.3.1379

[13]

10.1017/s0016672301005213

[14]

10.1038/352255a0

[15]

10.1046/j.1525-142x.2003.03030.x

[16]

10.1017/s0016672300030500

[17]

10.1093/humrep/15.suppl_2.102

[18]

10.1098/rspb.1992.0053

[19]

Hurst L. D. "Selfish genetic elements and their role in evolution ‐ the evolution of sex and some of what that entails" Mol. Biol. Cell (1995)

[20]

10.1073/pnas.92.10.4542

[21]

10.1093/genetics/126.3.657

[22]

10.1017/s0016672300030287

[23]

10.1126/science.1096342

[24]

10.1111/j.1558-5646.1986.tb00468.x

[25]

10.1098/rspb.2000.1169

[26]

10.1093/oxfordjournals.molbev.a003904

[27]

10.1093/molbev/msr007

[28]

10.1266/jjg.62.225

[29]

10.1017/s0016672306008123

[30]

Magoulas A. "Restriction‐site heteroplasmy in anchovy (Engraulis encrasicolus) indicates incidental biparental inheritance of mitochondrial‐DNA" Mol. Biol. Evol. (1993)

[31]

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, D.D. Dykes, H.F. Polesky

Nucleic Acids Research 10.1093/nar/16.3.1215

[32]

10.1016/0027-5107(64)90047-8

[33]

10.1098/rspb.2008.1758

[34]

10.1111/mec.12256

[35]

A Broad Survey of Recombination in Animal Mitochondria

Gwenael Piganeau, Michael Gardner, Adam Eyre-Walker

Molecular Biology and Evolution 10.1093/molbev/msh244

[36]

10.1007/s10709-011-9576-y

[37]

10.1016/s0169-5347(03)00125-3

[38]

10.1056/nejmoa020350

[39]

10.1266/ggs.81.399

[40]

10.1093/genetics/148.2.851

[41]

Evolution, Weighting, and Phylogenetic Utility of Mitochondrial Gene Sequences and a Compilation of Conserved Polymerase Chain Reaction Primers

Chris Simon, Francesco Frati, Andrew Beckenbach et al.

Annals of the Entomological Society of America 10.1093/aesa/87.6.651

[42]

Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA

James Bruce Stewart, Christoph Freyer, Joanna L Elson et al.

PLOS Biology 10.1371/journal.pbio.0060010

[43]

10.1038/46466

[44]

10.1095/biolreprod63.2.582

[45]

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

K. Tamura, D. Peterson, N. Peterson et al.

Molecular Biology and Evolution 10.1093/molbev/msr121

[46]

Multiple Sequence Alignment Using ClustalW and ClustalX

Julie D. Thompson, Toby. J. Gibson, Des G. Higgins

Current Protocols in Bioinformatics 10.1002/0471250953.bi0203s00

[47]

Widespread Recombination in Published Animal mtDNA Sequences1

A. D. Tsaousis, D. P. Martin, E. D. Ladoukakis et al.

Molecular Biology and Evolution 10.1093/molbev/msi084

[48]

Williamson D. "Timeline ‐ the curious history of yeast mitochondrial DNA" Nat. Rev. Genet. (2002) 10.1038/nrg814

[49]

10.1038/hdy.2012.60

[50]

10.1016/j.tig.2005.03.006

Showing 50 of 51 references

Metrics

53

Citations

51

References

Details

Published: Jun 19, 2014
Vol/Issue: 4(13)
Pages: 2633-2641
License: View

Authors

E

Emmanouil Dokianakis

Department of Biology University of Crete 70013 Iraklion Crete Greece

E

Emmanuel D. Ladoukakis

Department of Biology University of Crete 70013 Iraklion Crete Greece

Cite This Article

Emmanouil Dokianakis, Emmanuel D. Ladoukakis (2014). Different degree of paternal mtDNA leakage between male and female progeny in interspecific Drosophila crosses. Ecology and Evolution, 4(13), 2633-2641. https://doi.org/10.1002/ece3.1069

Different degree of paternal mtDNA leakage between male and female progeny in interspecific Drosophila crosses

You May Also Like