journal article Aug 27, 2014

Effects of Person-Centred and Integrated Chronic Heart Failure and Palliative Home Care. PREFER: A Randomized Controlled Study

Abstract
Abstract

Aims
We evaluated the outcome of person-centred and integrated Palliative advanced home caRE and heart FailurE caRe (PREFER) with regard to patient symptoms, health-related quality of life (HQRL), and hospitalizations compared with usual care.


Methods and results
From January 2011 to October 2012, 36 (26 males, 10 females, mean age 81.9 years) patients with chronic heart failure (NYHA class III–IV) were randomized to PREFER and 36 (25 males, 11 females, mean age 76.6 years) to the control group at a single centre. Prospective assessments were made at 1, 3, and 6 months using the Edmonton Symptom Assessment Scale, Euro Qol, Kansas City Cardiomyopathy Questionnaire, and rehospitalizations. Between-group analysis revealed that patients receiving PREFER had improved HRQL compared with controls (57.6 ± 19.2 vs. 48.5 ± 24.4, age-adjusted P-value = 0.05). Within-group analysis revealed a 26% improvement in the PREFER group for HRQL (P = 0.046) compared with 3% (P = 0.82) in the control group. Nausea was improved in the PREFER group (2.4 ± 2.7 vs. 1.7 ± 1.7, P = 0.02), and total symptom burden, self-efficacy, and quality of life improved by 18% (P = 0.035), 17% (P = 0.041), and 24% (P = 0.047), respectively. NYHA class improved in 11 of the 28 (39%) PREFER patients compared with 3 of the 29 (10%) control patients (P = 0.015). Fifteen rehospitalizations (103 days) occurred in the PREFER group, compared with 53 (305 days) in the control group.


Conclusion
Person-centred care combined with active heart failure and palliative care at home has the potential to improve quality of life and morbidity substantially in patients with severe chronic heart failure.
Trial registration: NCT01304381
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References
30
[1]
Dickstein "ESC Committee for Practice Guidelines (CPG). ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)" Eur Heart J (2008) 10.1093/eurheartj/ehn309
[2]
Beernaert "Referral to palliative care in COPD and other chronic diseases: a population-based study" Resp Med (2013) 10.1016/j.rmed.2013.06.003
[3]
McDonagh "European Society of Cardiology Heart Failure Association Committee on Patient Care. European Society of Cardiology Heart Failure Association Standards for delivering heart failure care" Eur J Heart Fail (2011) 10.1093/eurjhf/hfq221
[4]
Brannstrom "Unequal care for dying patients in Sweden: a comparative registry study of deaths from heart disease and cancer" Eur J Cardiovasc Nurs (2012) 10.1016/j.ejcnurse.2011.06.007
[5]
Jaarsma "Advanced Heart Failure Study Group of the HFA of the ESC Palliative care in heart failure: a position statement from the palliative care workshop of the Heart Failure Association of the European Society of Cardiology" Eur J Heart Fail (2009) 10.1093/eurjhf/hfp041
[6]
World Health Organization (2002)
[7]
Evangelista "Examining the effects of an outpatient palliative care consultation on symptom burden, depression, and quality of life in patients with symptomatic heart failure" J Card Fail (2012) 10.1016/j.cardfail.2012.10.019
[8]
Gomes "Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers" Cochrane Database Syst Rev (2013)
[9]
Brannstrom "A new model for integrated heart failure and palliative advanced homecare—rationale and design of a prospective randomized study" Eur J Cardiovasc Nurs (2013) 10.1177/1474515112445430
[10]
Jonsson "Heart failure registry: a valuable tool for improving the management of patients with heart failure" Eur J Heart Fail (2010) 10.1093/eurjhf/hfp175
[11]
Ekman "Person-centered care—ready for prime time" Eur J Cardiovasc Nurs (2011) 10.1016/j.ejcnurse.2011.06.008
[12]
Ternestedt (2010)
[13]
Chang "Validation of the Edmonton Symptom Assessment Scale" Cancer (2000) 10.1002/(sici)1097-0142(20000501)88:9<2164::aid-cncr24>3.0.co;2-5
[14]
EuroQol "EuroQol—a new facility for the measurement of health-related quality of life" Health Policy (1990) 10.1016/0168-8510(90)90421-9
[15]
Ellis "Validation of the EQ-5D in patients with a history of acute coronary syndrome" Curr Med Res Opin (2005) 10.1185/030079905x56349
[16]
Patel "Psychometric properties of a Swedish version of the Kansas City Cardiomyopathy Questionnaire in a chronic heart failure population" Eur J Cardiovasc Nurs (2008) 10.1016/j.ejcnurse.2007.08.005
[17]
Follwell "Phase II study of an outpatient palliative care intervention in patients with metastatic cancer" J Clin Oncol (2009) 10.1200/jco.2008.17.7568
[18]
Brannstrom "Living with severe chronic heart failure in palliative advanced home care" Eur J Cardiovasc Nurs (2006) 10.1016/j.ejcnurse.2006.01.006
[19]
Brannstrom "Being a palliative nurse for persons with severe congestive heart failure in advanced homecare" Eur J Cardiovasc Nurs (2005) 10.1016/j.ejcnurse.2005.04.007
[20]
Ekman "Effects of person-centred care in patients with chronic heart failure: the PCC-HF study" Eur Heart J (2012) 10.1093/eurheartj/ehr306
[21]
Gillum (1996)
[22]
Ryden-Bergsten "The health care costs of heart failure in Sweden" J Intern Med (1999) 10.1046/j.1365-2796.1999.00520.x
[23]
Kossovsky "Relationship between hospital length of stay and quality of care in patients with congestive heart failure" Qual Saf Health Care (2002) 10.1136/qhc.11.3.219
[24]
Clarke "Length of in-hospital stay and its relationship to quality of care" Qual Saf Health Care (2002) 10.1136/qhc.11.3.209
[25]
Smith "Managing patients with multimorbidity: systematic review of interventions in primary care and community settings" BMJ (2012) 10.1136/bmj.e5205
[26]
Stromberg "Nurse-led heart failure clinics improve survival and self-care behaviour in patients with heart failure: results from a prospective, randomised trial" Eur Heart J (2003) 10.1016/s0195-668x(03)00112-x
[27]
Brannstrom "Physicians' experiences of palliative care for heart failure patients" Eur J Cardiovasc Nurs (2011) 10.1016/j.ejcnurse.2010.04.005
[28]
Hanratty "Doctors' perceptions of palliative care for heart failure: focus group study" BMJ (2002) 10.1136/bmj.325.7364.581
[29]
Ekman "Home-based management of patients with chronic heart failure—focus on content not just form!" Eur Heart J (2002) 10.1053/euhj.2002.3178
[30]
Buck "Caregivers' contributions to heart failure self-care: a systematic review" Eur J Cardiovasc Nurs (2014)
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Citations
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References
Details
Published
Aug 27, 2014
Vol/Issue
16(10)
Pages
1142-1151
License
View
Funding
Swedish Association of Local Authorities and Regions
Swedish Heart and Lung Association
Ronnbaret Foundation Skelleftea Municipality
Cite This Article
Margareta Brännström, Kurt Boman (2014). Effects of Person-Centred and Integrated Chronic Heart Failure and Palliative Home Care. PREFER: A Randomized Controlled Study. European Journal of Heart Failure, 16(10), 1142-1151. https://doi.org/10.1002/ejhf.151