journal article Open Access Sep 25, 2024

From structure to function: A comprehensive overview of polysaccharide roles and applications

Food Frontiers Vol. 6 No. 1 pp. 15-39 · Wiley
Abstract
AbstractPolysaccharides, also known as glycans, are biological macromolecules consisting of many monosaccharide units. Alongside proteins, nucleic acids, and lipids, they constitute the four fundamental substances crucial for life activities and essential for the growth and development of living organisms. As natural products with inherent biological activity, polysaccharides are widely available, nontoxic, and possess numerous functional properties, holding immense potential for advancement in food, medicine, and cosmetics. Furthermore, the exploration of polysaccharide‐based drugs, as an alternative to conventional therapies, emerges as a promising avenue for addressing future disease challenges. This article comprehensively reviews the sources, structural characteristics, synthesis, degradation, functions, and applications of polysaccharides. The potential of polysaccharides for pharmacological applications, in antitumor, antiaging, antioxidant, hypoglycemic, anti‐inflammatory, antiviral, and anticoagulant properties, is summarized. Additionally, the role of polysaccharides in environmental protection is discussed. It is anticipated that this review will offer innovative strategic insights, serving as a theoretical foundation and inspiration for the subsequent research on polysaccharides in healthcare.
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References
240
[13]
The potential of microalgae and their biopolymers as structuring ingredients in food: A review

Tom M.M. Bernaerts, Lore Gheysen, Imogen Foubert et al.

Biotechnology Advances 10.1016/j.biotechadv.2019.107419
[33]
Living on a break: cellular senescence as a DNA-damage response

Fabrizio d'Adda di Fagagna

Nature Reviews Cancer 10.1038/nrc2440
[40]
Rheological insight of polysaccharide/protein based hydrogels in recent food and biomedical fields: A review

Zhiping Fan, Ping Cheng, Pan Zhang et al.

International Journal of Biological Macromolecules 10.1016/j.ijbiomac.2022.10.082
[42]
Nitric oxide signalling in cardiovascular health and disease

Charlotte Farah, Lauriane Y. M. Michel, Jean-Luc Balligand

Nature Reviews Cardiology 10.1038/nrcardio.2017.224

Showing 50 of 240 references