PRKAA1 rs13361707 C/T polymorphism confers decreased susceptibility to esophageal cancer: A case‐control study
polymorphism, but obtained insignificant findings.MethodsIn this study, 814 EC cases and 961
controls from Eastern China were recruited to validate the relationship between this polymorphism and EC susceptibility.ResultsData suggested rs13361707 C/T
polymorphism in PRKAA1 gene was significantly related with a lower risk for EC. Such significant connection was also uncovered in subgroups of males, smokers, drinkers and individuals with age ≥ 60 years. In addition, this polymorphism
was linked with the pathological grading, distant metastasis, and histology of EC.ConclusionIn summary, PRKAA1 rs13361707 C/T
polymorphism is related to the risk and clinical properties of EC patients in East China.
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- Published
- Jun 02, 2020
- Vol/Issue
- 34(9)
- License
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