The accuracy of self‐reported drug ingestion histories in emergency department patients

Andrew A. Monte; Kennon J. Heard; Jason A. Hoppe; Vasilis Vasiliou; Frank J. Gonzalez

doi:10.1002/jcph.368

journal article Jul 28, 2014

The accuracy of self‐reported drug ingestion histories in emergency department patients

Andrew A. Monte

Kennon J. Heard Jason A. Hoppe Vasilis Vasiliou

Frank J. Gonzalez

The Journal of Clinical Pharmacology Vol. 55 No. 1 pp. 33-38 · Wiley

View at Publisher Save 10.1002/jcph.368

Abstract

AbstractInaccuracies in self‐reports may lead to duplication of therapy, failure to appreciate non‐compliance leading to exacerbation of chronic medical conditions, or inaccurate research conclusions. Our objective is to determine the accuracy of self‐reported drug ingestion histories in patients presenting to an urban academic emergency department (ED). We conducted a prospective cohort study in ED patients presenting for pain or nausea. We obtained a structured drug ingestion history including all prescription drugs, over‐the‐counter medication (OTC) drugs, and illicit drugs for the 48 hours prior to ED presentation. We obtained urine comprehensive drug screens (CDS) and determined self‐report/CDS concordance. Fifty‐five patients were enrolled. Self‐reported drug ingestion histories were poor in these patients; only 17 (30.9%) of histories were concordant with the CDS. For the individual drug classes, prescription drug‐CDS was concordant in 32 (58.2%), OTC‐CDS was concordant in 33 (60%), and illicit drug‐CDS was concordant in 45 (81.8%) of subjects. No demographic factors predicted an accurate self‐reported drug history. Sixteen patients had drugs detected by CDS that were unreported by history. Nine of these 16 included an unreported opioid. In conclusion, self‐reported drug ingestion histories are often inaccurate and resources are needed to confirm compliance and ensure unreported drugs are not overlooked.

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Metrics

39

Citations

29

References

Details

Published: Jul 28, 2014
Vol/Issue: 55(1)
Pages: 33-38
License: View

Authors

A

Andrew A. Monte

University of Colorado Department of Emergency Medicine Aurora CO USA; Skaggs School of Pharmacy and Pharmaceutical Sciences Aurora Colorado USA; Rocky Mountain Poison & Drug Center Denver Colorado USA

K

Kennon J. Heard

University of Colorado Department of Emergency Medicine Aurora CO USA; Rocky Mountain Poison & Drug Center Denver Colorado USA

J

Jason A. Hoppe

University of Colorado Department of Emergency Medicine Aurora CO USA; Rocky Mountain Poison & Drug Center Denver Colorado USA

V

Vasilis Vasiliou

Skaggs School of Pharmacy and Pharmaceutical Sciences Aurora Colorado USA

F

Frank J. Gonzalez

Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute Bethesda Maryland USA

Funding

National Institutes of Health Award: UL1 TR000154

Emergency Medicine Foundation Award: NA

Cite This Article

Andrew A. Monte, Kennon J. Heard, Jason A. Hoppe, et al. (2014). The accuracy of self‐reported drug ingestion histories in emergency department patients. The Journal of Clinical Pharmacology, 55(1), 33-38. https://doi.org/10.1002/jcph.368

The accuracy of self‐reported drug ingestion histories in emergency department patients

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