Porcine buccal mucosa as in vitro model: Effect of biological and experimental variables

Upendra Kulkarni; Ravichandran Mahalingam; Indiran Pather; Xiaoling Li; Bhaskara Jasti

doi:10.1002/jps.21907

journal article Mar 01, 2010

Porcine buccal mucosa as in vitro model: Effect of biological and experimental variables

Upendra Kulkarni Ravichandran Mahalingam Indiran Pather Xiaoling Li

Bhaskara Jasti

Journal of Pharmaceutical Sciences Vol. 99 No. 3 pp. 1265-1277 · Elsevier BV

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References

58

[1]

Kulkarni "Porcine buccal mucosa as an in vitro model: Relative contribution of epithelium and connective tissue as permeability barriers" J Pharm Sci (2009) 10.1002/jps.21436

[2]

Birudaraj "Advances in buccal drug delivery" Crit Rev Ther Drug Carrier Syst (2005) 10.1615/critrevtherdrugcarriersyst.v22.i3.20

[3]

Pather "Current status and the future of buccal drug delivery systems" Expert Opin Drug Deliv (2008) 10.1517/17425247.5.5.531

[4]

Smart "Buccal drug delivery" Expert Opin Drug Deliv (2005) 10.1517/17425247.2.3.507

[5]

Sudhakar "Buccal bioadhesive drug delivery-a promising option for orally less efficient drugs" J Control Release (2006) 10.1016/j.jconrel.2006.04.012

[6]

Wertz "Cellular and molecular basis of barrier function in oral epithelium" Crit Rev Ther Drug Carrier Syst (1991)

[7]

De Vries "Localization of the permeability barrier inside porcine buccal mucosa: A combined in vitro study of drug permeability, electrical resistance and tissue morphology" Int J Pharm (1991) 10.1016/0378-5173(91)90340-t

[8]

Xiang "Transbuccal delivery of 2',3'-dideoxycytidine: In vitro permeation study and histological investigation" Int J Pharm (2002) 10.1016/s0378-5173(01)00865-1

[9]

Shojaei "Transbuccal permeation of a nucleoside analog, dideoxycytidine: Effects of menthol as a permeation enhancer" Int J Pharm (1999) 10.1016/s0378-5173(99)00301-4

[10]

Hoogstraate "Effects of bile salts on transport rates and routes of FITC-labelled compounds across porcine buccal epithelium in vitro" J Control Release (1996) 10.1016/0168-3659(95)00187-5

[11]

Schroeder (1981)

[12]

Squier "The permeability of skin and oral mucosa to water and horseradish peroxidase as related to the thickness of the permeability barrier" J Invest Dermatol (1985) 10.1111/1523-1747.ep12264711

[13]

Veuillez "Permeation of a myristoylated dipeptide across the buccal mucosa: Topological distribution and evaluation of tissue integrity" Int J Pharm (2002) 10.1016/s0378-5173(01)00850-x

[14]

Zhang "In vitro methods for measuring permeability of the oral mucosa" (1996)

[15]

Le Brun "In vitro penetration of some ß-adrenoreceptor blocking drugs through porcine buccal mucosa" Int J Pharm (1989) 10.1016/0378-5173(89)90113-0

[16]

Kulkarni "Porcine buccal mucosa as an in vitro model: Relative contribution of epithelium and connective tissue as permeability barriers" J Pharm Sci (2008) 10.1002/jps.21436

[17]

De Boer "Drug absorption by sublingual and rectal routes" Br J Anaesth (1984) 10.1093/bja/56.1.69

[18]

Nicolazzo "The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa" J Pharm Sci (2003) 10.1002/jps.10505

[19]

Nicolazzo "Assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol" J Pharm Sci (2004) 10.1002/jps.10559

[20]

Rossi "Buccal delivery of acyclovir from films based on chitosan and polyacrylic acid" Pharm Dev Technol (2003) 10.1081/pdt-120018490

[21]

Squier "In-vitro permeability of porcine oral mucosa after epithelial separation, stripping and hydration" Arch Oral Biol (1985) 10.1016/0003-9969(85)90095-0

[22]

de Vries "Hydrogels for buccal drug delivery: Properties relevant for muco-adhesion" J Biomed Mater Res (1988) 10.1002/jbm.820221106

[23]

Galey "The in vitro permeability of skin and buccal mucosa to selected drugs and tritiated water" J Invest Dermatol (1976) 10.1111/1523-1747.ep12598596

[24]

Dowty "Transport of thyrotropin releasing hormone in rabbit buccal mucosa in vitro" Pharm Res (1992) 10.1023/a:1015883217858

[25]

Imbert "Buccal mucosa in vitro experiments. I. Confocal imaging of vital staining and MTT assays for the determination of tissue viability" J Control Release (1999) 10.1016/s0168-3659(98)00143-6

[26]

Lee "The effect of storage conditions on the permeability of porcine buccal mucosa" Arch Pharm Res (2002) 10.1007/bf02976616

[27]

Sandri "Assessment of chitosan derivatives as buccal and vaginal penetration enhancers" Eur J Pharm Sci (2004) 10.1016/j.ejps.2003.10.028

[28]

Sandri "Buccal penetration enhancement properties of N-trimethyl chitosan: Influence of quaternization degree on absorption of a high molecular weight molecule" Int J Pharm (2005) 10.1016/j.ijpharm.2005.03.017

[29]

Betul "Development and in vitro evaluation of a buccoadhesive pindolol tablet formulation" Drug Dev Ind Pharm (1998) 10.3109/03639049809085621

[30]

Celebi "Development and evaluation of a buccoadhesive propranolol tablet formulation" Pharmazie (1995)

[31]

Manganaro "The effects of permeabilizers on the in vitro penetration of propranolol through porcine buccal epithelium" Mil Med (1996) 10.1093/milmed/161.11.669

[32]

Diaz Del Consuelo "Evaluation of pig esophageal mucosa as a permeability barrier model for buccal tissue" J Pharm Sci (2005) 10.1002/jps.20409

[33]

Anlar "Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets" Pharm Res (1994) 10.1023/a:1018951323522

[34]

Veuillez "Comparison of the ex-vivo oral mucosal permeation of tryptophan-leucine (Trp-Leu) and its myristoyl derivative" Int J Pharm (1998) 10.1016/s0378-5173(98)00134-3

[35]

Chang "Comparison of glycosidase activities in epidermis, palatal epithelium and buccal epithelium" Comp Biochem Physiol B (1991) 10.1016/0305-0491(91)90096-v

[36]

Park "Development and evaluation of a biphasic buccal adhesive tablet for nicotine replacement therapy" Int J Pharm (2002) 10.1016/s0378-5173(02)00041-8

[37]

Iscan "Formulation and in vitro/in vivo evaluation of buccal bioadhesive captopril tablets" STP Pharma Sci (1998)

[38]

van der Bijl "Diffusion rates of vasopressin through human vaginal and buccal mucosa" Eur J Oral Sci (1998) 10.1046/j.0909-8836.1998.eos106509.x

[39]

van der Bijl "Effect of freezing on the permeability of human buccal and vaginal mucosa" S Afr J Sci (1998)

[40]

Lesch "The permeability of human oral mucosa and skin to water" J Dent Res (1989) 10.1177/00220345890680091101

[41]

Hoogstraate "Diffusion rates and transport pathways of fluorescein isothiocyanate (FITC)-labeled model compounds through buccal epithelium" Pharm Res (1994) 10.1023/a:1018949828548

[42]

Junginger "Recent advances in buccal drug delivery and absorption-in vitro and in vivo studies" J Control Release (1999) 10.1016/s0168-3659(99)00032-2

[43]

Shojaei "Buccal mucosa as a route for systemic drug delivery: A review" J Pharm Pharm Sci (1998)

[44]

Babu "The influence of various methods of cold storage of skin on the permeation of melatonin and nimesulide" J Control Release (2003) 10.1016/s0168-3659(02)00368-1

[45]

Scaletta "A fine structural study of divalent cation mediated epithelial union with connective tissue in human oral mucosa" Am J Anat (1972) 10.1002/aja.1001330406

[46]

Garren "Buccal drug absorption. II: In vitro diffusion across the hamster cheek pouch" J Pharm Sci (1989) 10.1002/jps.2600780218

[47]

McCoy "Respiratory characteristics of mitochondria isolated from squamous epithelium of the hamster cheek pouch (39888)" Proc Soc Exp Biol Med (1977) 10.3181/00379727-156-39888

[48]

Person "Biochemical and histochemical studies of aerobic oxidative metabolism of oral tissues. 3. Specific metabolic activities of enzymatically separated gingival epithelium and connective-tissue components" J Dent Res (1965) 10.1177/00220345650440013601

[49]

Garren "Buccal absorption. III. Simultaneous diffusion and metabolism of an aminopeptidase substrate in the hamster cheek pouch" Pharm Res (1989) 10.1023/a:1015949614437

[50]

Artusi "Buccal delivery of thiocolchicoside: In vitro and in vivo permeation studies" Int J Pharm (2003) 10.1016/s0378-5173(02)00545-8

Showing 50 of 58 references

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Details

Published: Mar 01, 2010
Vol/Issue: 99(3)
Pages: 1265-1277
License: View

Authors

U

Upendra Kulkarni

R

Ravichandran Mahalingam

Cite This Article

Upendra Kulkarni, Ravichandran Mahalingam, Indiran Pather, et al. (2010). Porcine buccal mucosa as in vitro model: Effect of biological and experimental variables. Journal of Pharmaceutical Sciences, 99(3), 1265-1277. https://doi.org/10.1002/jps.21907

Porcine buccal mucosa as in vitro model: Effect of biological and experimental variables

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