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journal article Oct 21, 2020

Exclusion of Suicidal Participants From Randomized Controlled Trials for Posttraumatic Stress Disorder: A Meta‐Analysis

Emily Brooks Megan Spokas Deborah Goldschmidt
Journal of Traumatic Stress Vol. 34 No. 6 pp. 1209-1218 · Wiley
View at Publisher Save 10.1002/jts.22610
Abstract
AbstractThere has been a lack of consensus regarding whether to include or exclude participants with suicidal ideation (SI) from posttraumatic stress disorder (PTSD) psychotherapy clinical trials and, until recently, how best to report adverse events related to suicide risk. Without consistent reporting or evaluation of SI as an outcome, clinical practice guidelines are limited in their ability to recommend interventions for this common co‐occurrence. In the present meta‐analysis, we compared randomized controlled trials (RCTs) of PTSD psychotherapies, based on their suicide exclusion criteria. The databases PILOTS, PsycINFO, and PubMed were searched for RCTs of psychotherapy that lasted more than 4 weeks and included adults who met the diagnostic criteria for PTSD. Included studies (N = 48) were coded by two independent reviewers. A random‐effects model was used to calculate the pooled effect sizes for trials that excluded (n = 31) and did not exclude SI (n = 17). A test statistic for the significance of effect revealed that the difference between these two groups’ effect sizes was not significant, z = 0.96, p = .341. This suggests that the effects observed in clinical trials are not significantly impacted by SI‐related exclusion criteria.
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References
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Metrics
11
Citations
31
References
Details
Published
Oct 21, 2020
Vol/Issue
34(6)
Pages
1209-1218
License
View
Authors
E
Emily Brooks

Department of Psychology La Salle University Philadelphia Pennsylvania USA

M
Megan Spokas

Department of Psychology La Salle University Philadelphia Pennsylvania USA

D
Deborah Goldschmidt

Department of Psychology La Salle University Philadelphia Pennsylvania USA

Cite This Article
Emily Brooks, Megan Spokas, Deborah Goldschmidt (2020). Exclusion of Suicidal Participants From Randomized Controlled Trials for Posttraumatic Stress Disorder: A Meta‐Analysis. Journal of Traumatic Stress, 34(6), 1209-1218. https://doi.org/10.1002/jts.22610
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