journal article Open Access Mar 27, 2014

Obesity and the cardiovascular health effects of fine particulate air pollution

Obesity Vol. 22 No. 7 pp. 1580-1589 · Wiley
View at Publisher Save 10.1002/oby.20748
Abstract
ObjectiveThis review examines evidence related to the potential impact of obesity on the cardiovascular health effects of fine particulate air pollution (PM2.5).MethodsA PubMed search was conducted in December, 2013 and studies were included if they examined the relationship between PM2.5 and cardiovascular health as well as effect modification by obesity.ResultsOne hundred twenty‐one citations were reviewed; three large prospective cohort studies and 14 panel studies with short‐term follow‐up met the above criteria. All three cohort studies reported stronger associations between PM2.5 and cardiovascular mortality among obese subjects and one reported a significant trend of increased risk with increased body mass index. Similarly, 11 of 14 panel studies reported stronger associations between PM2.5 and acute changes in physiological measures of cardiovascular health among obese subjects including outcomes such as blood pressure and arrhythmia. Although interactions were not always statistically significant, the consistent pattern of stronger associations among obese subjects suggests that obesity may modify the impact of PM2.5 on cardiovascular health.ConclusionsEpidemiological evidence suggests that obesity may increase susceptibility to the cardiovascular health effects of PM2.5. This an important area of research as the public health impacts of air pollution could increase with increasing prevalence of obesity.
Topics

No keywords indexed for this article. Browse by subject →

References
45
[1]
WHO.World Health Organization fact sheet (Number 311) for worldwide prevalence of obesity.2013. Available online:http://www.who.int/mediacentre/factsheets/fs311/en/(accessed October 1 2013).
[3]
De Pergola G "Obesity as a major risk factor for cancer" J Obes (2013)
[4]
The Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects).Metabolic mediators of the effects of body‐mass index overweight and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1.8 million participants.Lancet2014;15:970–983. 10.1016/s0140-6736(13)61836-x
[15]
Weichenthal S "Long‐term exposure to fine particulate matter: Association with non‐accidental and cardiovascular mortality in the agricultural health study cohort" Environ Health Perspect
[28]
Chronic Residential Exposure to Particulate Matter Air Pollution and Systemic Inflammatory Markers

Barbara Hoffmann, Susanne Moebus, Nico Dragano et al.

Environmental Health Perspectives 10.1289/ehp.0800362
[35]
Heart Rate Variability

Task Force of the European Society of Cardiology the North A Electrophysiology

Circulation 10.1161/01.cir.93.5.1043
Metrics
92
Citations
45
References
Details
Published
Mar 27, 2014
Vol/Issue
22(7)
Pages
1580-1589
License
View
Cite This Article
Scott Weichenthal, Jane A. Hoppin, Francois Reeves (2014). Obesity and the cardiovascular health effects of fine particulate air pollution. Obesity, 22(7), 1580-1589. https://doi.org/10.1002/oby.20748