Insights into peptide and protein function: a convergent approach12

Bernard P. Roques

doi:10.1002/psc.315

journal article Feb 01, 2001

Insights into peptide and protein function: a convergent approach12

Bernard P. Roques

Journal of Peptide Science Vol. 7 No. 2 pp. 63-73 · Wiley

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Abstract

AbstractFrom viruses to multicellular organisms, life is inseparable from the genetic instructions aimed at regulating its maintenance, division, multiplication, differentiation and death (apoptosis). Over the past 15 years, structural studies have begun to resolve the complex reactions involved in these fundamental processes in biology. The three‐dimensional representations of the complexes formed with peptides and/or proteins have allowed interpretation of the biochemical data and formulation of novel hypotheses about the control and execution of these processes. Moreover, they have opened the way to rational approaches for designing compounds able to interfere with these crucial events in normal or pathological conditions. Various results obtained in our laboratory in these fields are briefly summarized in this review. Copyright © 2001 European Peptide Society and John Wiley & Sons, Ltd.

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Published: Feb 01, 2001
Vol/Issue: 7(2)
Pages: 63-73
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Authors

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Bernard P. Roques

Contribution from the Département de Pharmacochimie Moléculaire et Structurale, INSERM U266, CNRS UMR 8600, UFR des Sciences Pharmaceutiques & Biologiques, 4, Avenue de l'Observatoire, 75270 Paris Cedex 06, France, Centre de Recherche en Calcul Appliqué, Bureau 400, 5160, Boulevard Décarie, Montréal, QUEBEC H3X 2H9 Canada, Département de Chimie, Université de Montréal, C.P. 6128, succursale A Montréal, Québec, Canada, and Center for Advanced Research in Biotechnology, Maryland Biotechnology Institute,...

Cite This Article

Bernard P. Roques (2001). Insights into peptide and protein function: a convergent approach12. Journal of Peptide Science, 7(2), 63-73. https://doi.org/10.1002/psc.315

Insights into peptide and protein function: a convergent approach12

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