Effect of diphenolic laxatives on Na+-K+-activated ATPase and cyclic nucleotide content of rat colon mucosa in vivo

J. Schreiner; G. Nell; K. Loeschke

doi:10.1007/bf00505741

journal article Sep 01, 1980

Effect of diphenolic laxatives on Na+-K+-activated ATPase and cyclic nucleotide content of rat colon mucosa in vivo

Archiv für Experimentelle Pathologie und Pharmakologie Vol. 313 No. 3 pp. 249-255 · Springer Science and Business Media LLC

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References

37

[1]

Bartlett, G.: Phosphorus assay in column chromatography. J. Biol. Chem. 234, 466?468 (1959) 10.1016/s0021-9258(18)70226-3

[2]

Beubler, E., Juan, H.: PGE-mediated laxative effect of diphenolic laxatives. Naunyn-Schmiedeberg's Arch. Pharmacol. 305, 241?246 (1978) 10.1007/bf00498817

[3]

Beubler, E., Juan, H.: Effect of ricinoleic acid and other laxatives on net water flux and prostaglandin E release by the rat colon. J. Pharm. Pharmacol. 31, 681?685 (1979) 10.1111/j.2042-7158.1979.tb13628.x

[4]

Binder, H. J.: Pharmacology of laxatives. Ann. Rev. Pharmacol. Toxicol. 17, 355?367 (1977) 10.1146/annurev.pa.17.040177.002035

[5]

Brasitus, T. A., Field, M., Kimberg, D. V.: Intestinal mucosal cyclic GMP: regulation and relation to ion transport. Am. J. Physiol. 231, 275?282 (1976) 10.1152/ajplegacy.1976.231.1.275

[6]

Brostrom, C. O., Kon, C.: An improved protein binding assay for cyclic AMP. Analyt. Biochem. 58, 459?468 (1974) 10.1016/0003-2697(74)90214-0

[7]

Charney, A. N., Donowitz, M.: Functional significance of intestinal Na+?K+-ATPase: in vivo ouabain inhibition. Am. J. Physiol. 234, E629-E636 (1978)

[8]

Chignell, C. F.: The effect of phenolphthalein and other purgative drugs on rat intestinal (Na+?K+) adenosine triphosphatase. Biochem. Pharmacol. 17, 1207?1212 (1968) 10.1016/0006-2952(68)90057-9

[9]

Ewe, K.: Influence of diphenolic laxatives on water and electrolyte permeation in man. In: Intestinal permeation (M. Kramer and F. Lauterbach, eds.), pp. 420?426. Amsterdam, Oxford: Excerpta Medica 1977

[10]

Field, M.: Intracellular mediators of secretion in the small intestine. In: Mechanisms of intestinal secretion (H. J. Binder, ed.), pp. 83?91. New York: Alan R. Liss 1979

[11]

Field, M., Sheerin, H. E., Henderson, A., Smith, P. L.: Catecholamine effects on cyclic AMP levels and ion secretion in rabbit ileal mucosa. Am. J. Physiol. 229, 86?92 (1975) 10.1152/ajplegacy.1975.229.1.86

[12]

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

Cyrus H. Fiske, Yellapragada Subbarow

Journal of Biological Chemistry 1925 10.1016/s0021-9258(18)84756-1

[13]

Forth, W., Rummel, W.: Activation and inhibition of intestinal absorption by drugs. In: International encyclopedia of pharmacology and therapeutics Sec. 39B. pharmacology of intestinal absorption: Gastrointestial absorption of drugs, Vol. 1 (W. Forth and W. Rummel, eds.), pp. 171?244. Oxford: Pergamon Press 1975

[14]

Forth, W., Rummel, W., Baldauf, J. unter Mitarbeit von Andres, H. und Wilbert, H.: Wasser- und Elektrolytbewegung am Dünn-und Dickdarm unter dem Einfluß von Laxantien. Ein Beitrag zur Klärung ihres Wirkungsmechanismus. Naunyn-Schmiedebergs Arch. Pharmakol. Exp. Path. 254, 18?32 (1966) 10.1007/bf00537819

[15]

Forth, W., Nell, G., Rummel, W., Andres, H.: The hydragogue and laxative effect of the sulfuric acid ester and the free diphenol of 4,4?-dihydroxydiphenyl-(pyridyl-2)-methane. Naunyn-Schmiedeberg's Arch. Pharmacol. 274, 46?53 (1972) 10.1007/bf00501005

[16]

Gaginella, T. S., Bass, P.: Laxatives: an update on mechanism of action. Life Sci. 23, 1001?1010 (1978) 10.1016/0024-3205(78)90659-8

[17]

Gerzer, R., Loeschke, K.: Decreased cyclic GMP levels in rat cecum mucosa during adaptive stimulation of Na?K-ATPase. Experientia 35, 197?199 (1979) 10.1007/bf01920612

[18]

Harper, J. F., Brooker, G.: Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2?0-acetylation by acetic anhydride in aqueous solution. J. Cycl. Nucl. Res. 1, 207?218 (1975)

[19]

Loeschke K.: Na?K-ATPase and cAMP in diarrhoea due to diphenolic cathartics. Gastroenterol. Clin. Biol. 3, 179 (1979)

[20]

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

OliverH. Lowry, NiraJ. Rosebrough, A. Lewis Farr et al.

Journal of Biological Chemistry 1951 10.1016/s0021-9258(19)52451-6

[21]

Nell, G., Overhoff, H., Forth, W., Kulenkampff, H., Specht, W., Rummel, W.: Influx and efflux of sodium in jejunal and colonic segments of rats under the influence of oxyphenisatin. Naunyn-Schmiedebergs Arch. Pharmacol. 277, 53?60 (1973) 10.1007/bf00498784

[22]

Nell, G., Forth, W., Rummel, W., Wanitschke, R.: Pathway of sodium moving from blood to intestinal lumen under the influence of oxyphenisatin and deoxycholate. Naunyn-Schmiedebergs Arch. Pharmacol. 293, 31?37 (1976) 10.1007/bf00498868

[23]

Nell, G., Rummel, W., Wanitschke, R.: Characterization of the paracellular pathway by test molecules in colonic mucosa. In: Intestinal permeation (M. Kramer and F. Lauterbach, eds.), pp. 413?419. Amsterdam, Oxford: Excerpta Medica 1977

[24]

Nellans, H. N., Schultz, S. G.: Relations among transepithelial sodium transport, potassium exchange, and cell volume in rabbit ileum. J. Gen. Physiol. 68, 441?463 (1976) 10.1085/jgp.68.4.441

[25]

Powell, D. W., Lawrence, B. A., Morris, S. M., Etheridge, D. R.: Effect of phenolphthalein on in vitro rabbit ileal electrolyte transport. Gastroenterology 78, 454?463 (1980) 10.1016/0016-5085(80)90856-2

[26]

Rachmilewitz, D., Karmeli, F.: Effect of bisacodyl and dioctyl sodium sulfosuccinate on rat intestinal prostaglandin E2 content, Na?K-ATPase and adenyl cyclase activities. Gastroenterology 76, 1221 (1979)

[27]

Read, N. W., Krejs, G. J., Jones, V. E., Fordtran, J. S.: Effect of ouabain on Na?K-ATPase and electrolyte transport in the dog ileum in vivo. Gut 20, 356?365 (1979) 10.1136/gut.20.5.356

[28]

Rummel, W., Nell, G., Wanitschke, R.: Action mechanisms of antiabsorptive and hydragogue drugs. In: Intestinal absorption and malabsorption (T. Z. Csaky, ed.), pp. 209?227. New York: Raven Press 1975

[29]

Schiffl, H., Loeschke, K.: Induction of Na?K-ATPase in plasma membranes of rat cecum mucosa by diet: Time course and kinetics. Pflügers Arch. 372, 83?90 (1977) 10.1007/bf00582210

[30]

Schultz, S. G., Frizzell, R. A., Nellans, H. N.: Ion transport by mammalian small intestine. Ann. Rev. Physiol. 36, 51?91 (1974) 10.1146/annurev.ph.36.030174.000411

[31]

Sheerin, H. E., Field, M.: Ileal mucosal cyclic AMP and Cl secretion: serosal or mucosal addition of cholera toxin. Am. J. Physiol. 232, E210-E215 (1977)

[32]

Sund, R. B., Hillestad, B.: Diphenolic laxatives and intestinal cAMP: experiments with oxyphenisatin in the rat in vivo. Acta Pharmacol. Toxicol. 42, 321?322 (1978) 10.1111/j.1600-0773.1978.tb02210.x

[33]

Sund, R. B., Hol, L., Storbråten, A.: Studies in the rat on the absorption, biliary excretion, laxative action and interference with intestinal transport of some oxyphenisatin derivatives. Acta Pharmacol. Toxicol. 44, 251?259 (1979) 10.1111/j.1600-0773.1979.tb02326.x

[34]

Wanitschke, R., Soergel, K. H.: Effect of deoxycholate and oxyphenisatin on isolated rat colonic mucosa. Clin. Res. 23, 520A (1975)

[35]

Wanitschke, R., Nell, G., Rummel, W.: Influence of hydrostatic pressure gradients on net transfer of sodium and water across isolated rat colonic mucosa. Naunyn-Schmiedebergs Arch. Pharmacol. 297, 191?194 (1977b) 10.1007/bf00499930

[36]

Wanitschke, R., Nell, G., Rummel, W., Specht, W.: Transfer of sodium and water through isolated rat colonic mucosa under the influence of deoxycholate and oxyphenisatin. Naunyn-Schmiedebergs Arch. Pharmacol. 297, 185?190 (1977a) 10.1007/bf00499929

[37]

Weber, E.: Grundriß der biologischen Statistik, p. 260. Stuttgart: Gustav Fischer Verlag 1967

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Published: Sep 01, 1980
Vol/Issue: 313(3)
Pages: 249-255
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Cite This Article

J. Schreiner, G. Nell, K. Loeschke (1980). Effect of diphenolic laxatives on Na+-K+-activated ATPase and cyclic nucleotide content of rat colon mucosa in vivo. Archiv für Experimentelle Pathologie und Pharmakologie, 313(3), 249-255. https://doi.org/10.1007/bf00505741

Effect of diphenolic laxatives on Na+-K+-activated ATPase and cyclic nucleotide content of rat colon mucosa in vivo

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