journal article Open Access Jun 01, 2021

Triple growth factor delivery promotes functional bone regeneration following composite musculoskeletal trauma

Acta Biomaterialia Vol. 127 pp. 180-192 · Elsevier BV
View at Publisher Save 10.1016/j.actbio.2021.03.066
Topics

No keywords indexed for this article. Browse by subject →

References
66
[1]
Kim "Gustilo-Anderson classification" Clin. Orthop. Relat. Res.® (2012) 10.1007/s11999-012-2376-6
[2]
Hurtgen "Severe muscle trauma triggers heightened and prolonged local musculoskeletal inflammation and impairs adjacent tibia fracture healing" J. Musculoskelet. Neuronal Interact. (2016)
[3]
Doukas "The Military Extremity Trauma Amputation/Limb Salvage (METALS) study: outcomes of amputation versus limb salvage following major lower-extremity trauma" J. Bone Joint Surg. Am. (2013) 10.2106/jbjs.k.00734
[4]
Amini "Bone tissue engineering: recent advances and challenges" Crit. Rev. Biomed. Eng. (2012) 10.1615/critrevbiomedeng.v40.i5.10
[5]
Aguilar "Multiscale analysis of a regenerative therapy for treatment of volumetric muscle loss injury" Cell Death Discov. (2018) 10.1038/s41420-018-0027-8
[6]
Utvag "Poor muscle coverage delays fracture healing in rats" Acta Orthop. Scand. (2002) 10.1080/00016470216315
[7]
Owston "Do skeletal muscle MSCs in humans contribute to bone repair? A systematic review" Injury (2016) 10.1016/s0020-1383(16)30834-8
[8]
Willett "Attenuated human bone morphogenetic protein-2-mediated bone regeneration in a rat model of composite bone and muscle injury" Tissue Eng. - Part C: Methods (2013) 10.1089/ten.tec.2012.0290
[9]
Ruehle "Effects of BMP-2 dose and delivery of microvascular fragments on healing of bone defects with concomitant volumetric muscle loss" J. Orthop. Res. (2019) 10.1002/jor.24225
[10]
Guldberg "Spatiotemporal delivery strategies for promoting musculoskeletal tissue regeneration" J. Bone Miner. Res. (2009) 10.1359/jbmr.090801
[11]
Subbiah "Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine" Adv. Healthc. Mater. (2019) 10.1002/adhm.201801000
[12]
Lee "Growth factor delivery-based tissue engineering: general approaches and a review of recent developments" J. R. Soc., Interface (2011) 10.1098/rsif.2010.0223
[13]
Begam "Strategies for delivering bone morphogenetic protein for bone healing" Mater. Sci. Eng. C Mater. Biol. Appl. (2017) 10.1016/j.msec.2016.09.074
[14]
Nyberg "Growth factor-eluting technologies for bone tissue engineering" Drug Deliv. Transl. Res. (2016) 10.1007/s13346-015-0233-3
[15]
Oest "Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects" J. Orthop. Res. (2007) 10.1002/jor.20372
[16]
Kolambkar "Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects" Bone (2011) 10.1016/j.bone.2011.05.010
[17]
Kolambkar "An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects" Biomaterials (2011) 10.1016/j.biomaterials.2010.08.074
[18]
Boerckel "Effects of in vivo mechanical loading on large bone defect regeneration" J. Orthop. Res. (2012) 10.1002/jor.22042
[19]
Krishnan "Hydrogel-based delivery of rhBMP-2 improves healing of large bone defects compared with autograft" Clin. Orthop. Relat. Res. (2015) 10.1007/s11999-015-4312-z
[20]
Boerckel "Effects of protein dose and delivery system on BMP-mediated bone regeneration" Biomaterials (2011) 10.1016/j.biomaterials.2011.03.063
[21]
Krishnan "Delivery vehicle effects on bone regeneration and heterotopic ossification induced by high dose BMP-2" Acta Biomater. (2017) 10.1016/j.actbio.2016.12.012
[22]
James "A review of the clinical side effects of bone morphogenetic protein-2" Tissue Eng. Part B Rev. (2016) 10.1089/ten.teb.2015.0357
[23]
Hettiaratchi "Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration" Sci. Adv. (2020) 10.1126/sciadv.aay1240
[24]
Li "Angiogenesis: A Control Point for Normal and Delayed Wound Healing" (2003)
[25]
Du "Fibroblast-derived matrix (FDM) as a novel vascular endothelial growth factor delivery platform" J. Control. Release (2014) 10.1016/j.jconrel.2014.08.026
[26]
Du "Vascular morphogenesis of human umbilical vein endothelial cells on cell-derived macromolecular matrix microenvironment" Tissue Eng.. Part A (2014) 10.1089/ten.tea.2013.0693
[27]
Choi "Dual growth factor delivery using biocompatible core-shell microcapsules for angiogenesis" Small (2013) 10.1002/smll.201300427
[28]
Krishnan "Vascularization strategies for bone regeneration" Ann. Biomed. Eng. (2014) 10.1007/s10439-014-0969-9
[29]
Boerckel "Mechanical regulation of vascular growth and tissue regeneration in vivo" PNAS (2011) 10.1073/pnas.1107019108
[30]
Lu "Ischemia leads to delayed union during fracture healing: a mouse model" J. Orthop. Res. (2007) 10.1002/jor.20264
[31]
Laschke "Adipose tissue-derived microvascular fragments: natural vascularization units for regenerative medicine" Trends Biotechnol. (2015) 10.1016/j.tibtech.2015.06.001
[32]
Phelps "Update on therapeutic vascularization strategies" Regen. Med. (2009) 10.2217/17460751.4.1.65
[33]
Ehrbar "The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis" Biomaterials (2008) 10.1016/j.biomaterials.2007.12.002
[34]
Richardson "Polymeric system for dual growth factor delivery" Nat. Biotech. (2001) 10.1038/nbt1101-1029
[35]
Place "Complexity in biomaterials for tissue engineering" Nat. Mater. (2009) 10.1038/nmat2441
[36]
Subbiah "Effects of controlled dual growth factor delivery on bone regeneration following composite bone-muscle injury" Acta Biomater. (2020) 10.1016/j.actbio.2020.07.026
[37]
Lienemann "Smart hydrogels for the augmentation of bone regeneration by endogenous mesenchymal progenitor cell recruitment" Adv. Sci. (2020) 10.1002/advs.201903395
[38]
Hoying "Angiogenic potential of microvessel fragments established in three-dimensional collagen gels" In vitro Cell. Dev. Biol.. Animal (1996) 10.1007/bf02723003
[39]
Ruehle "Decorin-supplemented collagen hydrogels for the co-delivery of bone morphogenetic protein-2 and microvascular fragments to a composite bone-muscle injury model with impaired vascularization" Acta Biomater. (2019) 10.1016/j.actbio.2019.01.045
[40]
Park "The three dimensional cues-integrated-biomaterial potentiates differentiation of human mesenchymal stem cells" Carbohydr. Polym. (2018) 10.1016/j.carbpol.2018.09.010
[41]
Hansen-Smith "Griffonia simplicifolia I: fluorescent tracer for microcirculatory vessels in nonperfused thin muscles and sectioned muscle" Microvasc. Res. (1988) 10.1016/0026-2862(88)90022-2
[42]
Banerjee "Epidemiology of extremity injuries in multiple trauma patients" Injury (2013) 10.1016/j.injury.2012.12.007
[43]
Gothard "Tissue engineered bone using select growth factors: a comprehensive review of animal studies and clinical translation studies in man" Eur. Cells Mater. (2014) 10.22203/ecm.v028a13
[44]
Oryan "Bone morphogenetic proteins: a powerful osteoinductive compound with non-negligible side effects and limitations" Biofactors (2014) 10.1002/biof.1177
[45]
Zara "High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo" Tissue Eng. Part A (2011) 10.1089/ten.tea.2010.0555
[46]
Carragee "A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned" Spine J. (2011) 10.1016/j.spinee.2011.04.023
[47]
Reyes "Effect of triple growth factor controlled delivery by a brushite–PLGA system on a bone defect" Injury (2012) 10.1016/j.injury.2011.10.008
[48]
Subbiah "Osteogenic/angiogenic dual growth factor delivery microcapsules for regeneration of vascularized bone tissue" Adv. Healthc. Mater. (2015) 10.1002/adhm.201500341
[49]
Sharmin "Dual growth factor delivery from biofunctionalized allografts: sequential VEGF and BMP-2 release to stimulate allograft remodeling" J. Orthop. Res. (2017) 10.1002/jor.23287
[50]
Sharmin "Large scale segmental bone defect healing through the combined delivery of VEGF and BMP-2 from biofunctionalized cortical allografts" J. Biomed. Mater. Res. Part B: Appl. Biomater. (2019) 10.1002/jbm.b.34193

Showing 50 of 66 references

Related

You May Also Like

Conductive polymers: Towards a smart biomaterial for tissue engineering

Richard Balint, Nigel J. Cassidy · 2014

1,613 citations

Bioactive glass in tissue engineering

Mohamed N. Rahaman, Delbert E. Day · 2011

1,584 citations

Nanoscale hydroxyapatite particles for bone tissue engineering

Hongjian Zhou, Jaebeom Lee · 2011

1,379 citations

Synthesis methods for nanosized hydroxyapatite with diverse structures

Mehdi Sadat-Shojai, Mohammad-Taghi Khorasani · 2013

1,328 citations

Biomedical coatings on magnesium alloys – A review

H. Hornberger, S. Virtanen · 2012

1,191 citations