Plasma arginine/ADMA ratio as a sensitive risk marker for atherosclerosis: Shimane CoHRE study

Yoshitomo Notsu; Shozo Yano; Hiroshi Shibata; Atsushi Nagai; Toru Nabika

doi:10.1016/j.atherosclerosis.2014.12.030

journal article Mar 01, 2015

Plasma arginine/ADMA ratio as a sensitive risk marker for atherosclerosis: Shimane CoHRE study

Yoshitomo Notsu Shozo Yano

Hiroshi Shibata Atsushi Nagai

Toru Nabika

Atherosclerosis Vol. 239 No. 1 pp. 61-66 · Elsevier BV

View at Publisher Save 10.1016/j.atherosclerosis.2014.12.030

Topics

No keywords indexed for this article. Browse by subject →

References

48

[1]

Kielstein "ADMA increases arterial stiffness and decreases cerebral blood flow in humans" Stroke (2006) 10.1161/01.str.0000231640.32543.11

[2]

Böger "Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality–an update on patient populations with a wide range of cardiovascular risk" Pharmacol. Res. (2009) 10.1016/j.phrs.2009.07.001

[3]

Baylis "Nitric oxide synthase derangements and hypertension in kidney disease" Curr. Opin. Nephrol. Hypertens. (2012) 10.1097/mnh.0b013e32834d54ca

[4]

Zoccali "Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study" Lancet (2001) 10.1016/s0140-6736(01)07217-8

[5]

Nijveldt "Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality" Clin. Nutr. (2003) 10.1054/clnu.2002.0613

[6]

Krzyzanowska "Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes" Diabetes Care (2007) 10.2337/dc07-0019

[7]

Anderssohn "Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus" Diabetes Vasc. Dis. Res. (2010) 10.1177/1479164110366053

[8]

Abedini "Asymmetrical dimethylarginine is associated with renal and cardiovascular outcomes and all-cause mortality in renal transplant recipients" Kidney Int. (2010) 10.1038/ki.2009.382

[9]

The L-Arginine–Asymmetric Dimethylarginine Ratio is an Independent Predictor of Mortality in Dilated Cardiomyopathy

Maike Anderssohn, Mark Rosenberg, Edzard Schwedhelm et al.

Journal of Cardiac Failure 2012 10.1016/j.cardfail.2012.10.011

[10]

Böger "Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease" J. Intern. Med. (2011) 10.1111/j.1365-2796.2010.02322.x

[11]

Chirinos "Endogenous nitric oxide synthase inhibitors, arterial hemodynamics, and subclinical vascular disease: the PREVENCION Study" Hypertension (2008) 10.1161/hypertensionaha.108.120352

[12]

Furuki "Plasma levels of asymmetric dimethylarginine (ADMA) are related to intima-media thickness of the carotid artery: an epidemiological study" Atherosclerosis (2007) 10.1016/j.atherosclerosis.2006.03.022

[13]

Zsuga "Serum asymmetric dimethylarginine negatively correlates with intima-media thickness in early-onset atherosclerosis" Cerebrovasc. Dis. (2007) 10.1159/000101461

[14]

Kanazawa "Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus" Clin. Endocrinol. (Oxf) (2011) 10.1111/j.1365-2265.2010.03946.x

[15]

Maas "Association of the endogenous nitric oxide synthase inhibitor ADMA with carotid artery intimal media thickness in the Framingham Heart Study offspring cohort" Stroke (2009) 10.1161/strokeaha.109.552539

[16]

Luiking "Arginine de novo and nitric oxide production in disease states" Am. J. Physiol. Endocrinol. Metab. (2012) 10.1152/ajpendo.00284.2012

[17]

Wijnands "Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated no production during endotoxemia" PLoS One (2014) 10.1371/journal.pone.0086135

[18]

Bode-Böger "The L-arginine paradox: importance of the L-arginine/asymmetrical dimethylarginine ratio" Pharmacol. Ther. (2007) 10.1016/j.pharmthera.2007.03.002

[19]

Ellger "Glycemic control modulates arginine and asymmetrical-dimethylarginine levels during critical illness by preserving dimethylarginine-dimethylaminohydrolase activity" Endocrinology (2008) 10.1210/en.2007-1558

[20]

Visser "Imbalance of arginine and asymmetric dimethylarginine is associated with markers of circulatory failure, organ failure and mortality in shock patients" Br. J. Nutr. (2012) 10.1017/s0007114511004648

[21]

Staalsø "Low plasma arginine:asymmetric dimethyl arginine ratios predict mortality after intracranial aneurysm rupture" Stroke (2013) 10.1161/strokeaha.111.000605

[22]

Notsu "Evaluation of asymmetric dimethylarginine and homocysteine in microangiopathy-related cerebral damage" Am. J. Hypertens. (2009) 10.1038/ajh.2008.346

[23]

Hamano "Contributions of social context to blood pressure: findings from a multilevel analysis of social capital and systolic blood pressure" Am. J. Hypertens. (2011) 10.1038/ajh.2011.37

[24]

Hamano "Effect of environmental and lifestyle factors on hypertension: Shimane COHRE study" PLoS One (2012) 10.1371/journal.pone.0049122

[25]

Imai "Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease" Clin. Exp. Nephrol. (2007) 10.1007/s10157-006-0453-4

[26]

Dobashi "An automated analyzer for methylated arginines in rat plasma by HPLC with post-column fluorescence reaction" Analyst (2002) 10.1039/b106828h

[27]

Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond

Michael J. Pencina, Ralph B. D' Agostino, Ramachandran S. Vasan

Statistics in Medicine 2008 10.1002/sim.2929

[28]

Polak "Carotid-wall intima-media thickness and cardiovascular events" N. Engl. J. Med. (2011) 10.1056/nejmoa1012592

[29]

Polak "The value of carotid artery plaque and intima-media thickness for incident cardiovascular disease: the multi-ethnic study of atherosclerosis" J. Am. Heart Assoc. (2013) 10.1161/jaha.113.000087

[30]

Baldassarre J. Am. Coll. Cardiol. (2012) 10.1016/j.jacc.2012.06.034

[31]

Böger "Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community" Circulation (2009) 10.1161/circulationaha.108.838268

[32]

Pizzarelli "Asymmetric dimethylarginine predicts survival in the elderly" Age (Dordr) (2013) 10.1007/s11357-013-9523-1

[33]

Zoccali "Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease" J. Am. Soc. Nephrol. (2002) 10.1681/asn.v132490

[34]

Nanayakkara "Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure" Kidney Int. (2005) 10.1111/j.1523-1755.2005.00680.x

[35]

Cobanoglu "Role of asymmetric dimethylarginine in the progression of carotid atherosclerosis in renal transplant patients" Int. Urol. Nephrol. (2013) 10.1007/s11255-012-0345-3

[36]

Xia "Asymmetric dimethylarginine and carotid atherosclerosis in Type 2 diabetes mellitus" J. Endocrinol. Invest. (2012) 10.1007/bf03347101

[37]

Serg "Association between asymmetric dimethylarginine and indices of vascular function in patients with essential hypertension" Blood Press. (2011) 10.3109/08037051.2010.533821

[38]

Furuki "Plasma level of asymmetric dimethylarginine (ADMA) as a predictor of carotid intima-media thickness progression: six-year prospective study using carotid ultrasonography" Hypertens. Res. (2008) 10.1291/hypres.31.1185

[39]

Bai "Association of circulating levels of asymmetric dimethylarginine (ADMA) with carotid intima-media thickness: evidence from 6168 participants" Ageing Res. Rev. (2013) 10.1016/j.arr.2012.02.003

[40]

Masuda "Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycemia" Br. J. Pharmacol. (1999) 10.1038/sj.bjp.0702298

[41]

Cardounel "Endogenous methylarginines regulate neuronal nitric-oxide synthase and prevent excitotoxic injury" J. Biol. Chem. (2002) 10.1074/jbc.m108983200

[42]

Cardounel "Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function" J. Biol. Chem. (2007) 10.1074/jbc.m603606200

[43]

Teerlink "Cellular ADMA: regulation and action" Pharmacol. Res. (2009) 10.1016/j.phrs.2009.08.002

[44]

Jaenecke "A chimera carrying the functional domain of the orphan protein SLC7A14 in the backbone of SLC7A2 mediates trans-stimulated arginine transport" J. Biol. Chem. (2012) 10.1074/jbc.m112.350322

[45]

Lind "L-Arginine is related to endothelium-dependent vasodilation in resistance and conduit arteries in divergent ways-The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study" Atherosclerosis (2009) 10.1016/j.atherosclerosis.2008.07.016

[46]

Nicholls "Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction" Circulation (2007) 10.1161/circulationaha.107.693986

[47]

Schlaich "Impaired L-arginine transport and endothelial function in hypertensive and genetically predisposed normotensive subjects" Circulation (2004) 10.1161/01.cir.0000149748.79945.52

[48]

Davids "Plasma concentrations of arginine and asymmetric dimethylarginine do not reflect their intracellular concentrations in peripheral blood mononuclear cells" Metabolism (2013) 10.1016/j.metabol.2013.05.017

Metrics

61

Citations

48

References

Details

Published: Mar 01, 2015
Vol/Issue: 239(1)
Pages: 61-66
License: View

Authors

Funding

Grant-In-Aids for Scientific research, Kakenhi (C) Award: 24591230

Cite This Article

Yoshitomo Notsu, Shozo Yano, Hiroshi Shibata, et al. (2015). Plasma arginine/ADMA ratio as a sensitive risk marker for atherosclerosis: Shimane CoHRE study. Atherosclerosis, 239(1), 61-66. https://doi.org/10.1016/j.atherosclerosis.2014.12.030

Plasma arginine/ADMA ratio as a sensitive risk marker for atherosclerosis: Shimane CoHRE study

You May Also Like