A role for the mu opioid receptor in the antidepressant effects of buprenorphine

Shivon A. Robinson; Rebecca L. Erickson; Caroline A. Browne; Irwin Lucki

doi:10.1016/j.bbr.2016.10.050

journal article Feb 01, 2017

A role for the mu opioid receptor in the antidepressant effects of buprenorphine

Shivon A. Robinson Rebecca L. Erickson Caroline A. Browne Irwin Lucki

Behavioural Brain Research Vol. 319 pp. 96-103 · Elsevier BV

View at Publisher Save 10.1016/j.bbr.2016.10.050

Topics

No keywords indexed for this article. Browse by subject →

References

48

[1]

Almatroudi "Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice" J. Psychopharmacol. (2015) 10.1177/0269881115586937

[2]

Bansinath "Effects of the benzomorphan kappa-opiate, MR 2266 and its (+) enantiomer MR 2267, on thermonociceptive reactions in different strains of mice" Neurosci. Lett. (1990) 10.1016/0304-3940(90)90146-z

[3]

Bodkin "Buprenorphine treatment of refractory depression" J. Clin. Psychopharmacol. (1995) 10.1097/00004714-199502000-00008

[4]

Bodnoff "A comparison of the effects of diazepam versus several typical and atypical anti-depressant drugs in an animal model of anxiety" Psychopharmacology (1989) 10.1007/bf00442264

[5]

Bodnoff "The effects of chronic antidepressant treatment in an animal model of anxiety" Psychopharmacology (1988) 10.1007/bf00181937

[6]

Browne "Antidepressant-like effects of buprenorphine in rats are strain dependent" Behav. Brain Res. (2015) 10.1016/j.bbr.2014.10.014

[7]

The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors

M.R. Bruchas, B.B. Land, C. Chavkin

Brain Research 2010 10.1016/j.brainres.2009.08.062

[8]

Bruchas "CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior" PLoS One (2009) 10.1371/journal.pone.0008528

[9]

Carlezon "Depressive-like effects of the kappa-opioid receptor agonist salvinorin A on behavior and neurochemistry in rats" J. Pharmacol. Exp. Therap. (2006) 10.1124/jpet.105.092304

[10]

Carr "Antidepressant-like effects of kappa-opioid receptor antagonists in Wistar Kyoto rats" Neuropsychopharmacology (2010) 10.1038/npp.2009.183

[11]

Contet "Mu opioid receptor: a gateway to drug addiction" Curr. Opin. Neurobiol. (2004) 10.1016/j.conb.2004.05.005

[12]

Cowan "Agonist and antagonist properties of buprenorphine, a new antinociceptive agent" Br. J. Pharmacol. (1977) 10.1111/j.1476-5381.1977.tb07532.x

[13]

Devine "Mesolimbic dopamine neurotransmission is increased by administration of mu-opioid receptor antagonists" Eur. J. Pharmacol. (1993) 10.1016/0014-2999(93)90167-g

[14]

Dulawa "Recent advances in animal models of chronic antidepressant effects: the novelty-induced hypophagia test" Neurosci. Biobehav. Rev. (2005) 10.1016/j.neubiorev.2005.03.017

[15]

Ehrich "Evaluation of opioid modulation in major depressive disorder" Neuropsychopharmacology (2015) 10.1038/npp.2014.330

[16]

Falcon "Effects of buprenorphine on behavioral tests for antidepressant and anxiolytic drugs in mice" Psychopharmacology (2015) 10.1007/s00213-014-3723-y

[17]

Falcon "Antidepressant-like effects of buprenorphine are mediated by kappa opioid receptors" Neuropsychopharmacology (2016) 10.1038/npp.2016.38

[18]

Filliol "Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses" Nat. Gen. (2000) 10.1038/76061

[19]

Gamble-George "Cyclooxygenase-2 inhibition reduces stress-induced affective pathology" eLife (2016) 10.7554/elife.14137

[20]

Gomes "Heterodimerization of mu and delta opioid receptors: a role in opiate synergy" J. Neurosci. (2000) 10.1523/jneurosci.20-22-j0007.2000

[21]

Two short-acting kappa opioid receptor antagonists (zyklophin and LY2444296) exhibited different behavioral effects from the long-acting antagonist norbinaltorphimine in mouse anxiety tests

Peng Huang, Tatyana Yakovleva, Jane V. Aldrich et al.

Neuroscience Letters 2016 10.1016/j.neulet.2016.01.017

[22]

Ide "Reduced emotional and corticosterone responses to stress in mu-opioid receptor knockout mice" Neuropharmacology (2010) 10.1016/j.neuropharm.2009.07.005

[23]

Opioids excite dopamine neurons by hyperpolarization of local interneurons

SW Johnson, RA North

The Journal of Neuroscience 1992 10.1523/jneurosci.12-02-00483.1992

[24]

Kieffer "Exploring the opioid system by gene knockout" Prog. Neurobiol. (2002) 10.1016/s0301-0082(02)00008-4

[25]

Knoll "Anxiolytic-like effects of kappa-opioid receptor antagonists in models of unlearned and learned fear in rats" J. Pharmacol. Exp. Therap. (2007) 10.1124/jpet.107.127415

[26]

Lalanne "The kappa opioid receptor: from addiction to depression, and back" Front Psychiatry (2014) 10.3389/fpsyt.2014.00170

[27]

Latagliata "Stress-induced activation of ventral tegmental mu-opioid receptors reduces accumbens dopamine tone by enhancing dopamine transmission in the medial pre-frontal cortex" Psychopharmacology (2014) 10.1007/s00213-014-3549-7

[28]

Lutfy "Buprenorphine: a unique drug with complex pharmacology" Curr. Neuropharmacol. (2004) 10.2174/1570159043359477

[29]

Lutz "The multiple facets of opioid receptor function: implications for addiction" Curr. Opin. Neurobiol. (2013) 10.1016/j.conb.2013.02.005

[30]

Mague "Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats" J. Pharmacol. Exp. Therap. (2003) 10.1124/jpet.102.046433

[31]

Marki "Mu-opioid receptor specific antagonist cyprodime: characterization by in vitro radioligand and [35S]GTPgammaS binding assays" Eur. J. Pharmacol. (1999) 10.1016/s0014-2999(99)00610-x

[32]

Matthes "Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene" Nature (1996) 10.1038/383819a0

[33]

McLaughlin "Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses" J. Neurosci. (2003) 10.1523/jneurosci.23-13-05674.2003

[34]

McLaughlin "Prior activation of kappa opioid receptors by U50,488 mimics repeated forced swim stress to potentiate cocaine place preference conditioning" Neuropsychopharmacology (2006) 10.1038/sj.npp.1300860

[35]

McLaughlin "Social defeat stress-Induced behavioral responses are mediated by the endogenous kappa opioid system" Neuropsychopharmacology (2006) 10.1038/sj.npp.1300872

[36]

Menzies "Ghrelin, reward and motivation" Endocr. Dev. (2013) 10.1159/000346058

[37]

Nyhuis "Opiate treatment in depression refractory to antidepressants and electroconvulsive therapy" J. Clin. Psychopharmacol. (2008) 10.1097/jcp.0b013e31818638a4

[38]

Papaleo "Decreased motivation to eat in mu-opioid receptor-deficient mice" Eur. J. Neurosci. (2007) 10.1111/j.1460-9568.2007.05595.x

[39]

Redila "Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system" Psychopharmacology (2008) 10.1007/s00213-008-1122-y

[40]

Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant‐like effects

Yukihiko Shirayama, Hisahito Ishida, Masaaki Iwata et al.

Journal of Neurochemistry 2004 10.1111/j.1471-4159.2004.02589.x

[41]

Slowe "Quantitative autoradiography of mu-,delta- and kappa1 opioid receptors in kappa-opioid receptor knockout mice" Brain Res. (1999) 10.1016/s0006-8993(98)01201-3

[42]

Spanagel "Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway" PNAS (1992) 10.1073/pnas.89.6.2046

[43]

Buprenorphine antagonism of mu opioids in the rhesus monkey tail-withdrawal procedure.

E A Walker, G Zernig, J H Woods

The Journal of Pharmacology and Experimental Thera... 1995 10.1016/s0022-3565(25)09651-x

[44]

Wiley "Kappa-opioid system regulates the long-lasting behavioral adaptations induced by early-life exposure to methylphenidate" Neuropsychopharmacology (2009) 10.1038/npp.2008.188

[45]

Wilson "The role of amygdalar mu-opioid receptors in anxiety-related responses in two rat models" Neuropsychopharmacology (2008) 10.1038/sj.npp.1301675

[46]

Wittmann "Prodynorphin-derived peptides are critical modulators of anxiety and regulate neurochemistry and corticosterone" Neuropsychopharmacology (2009) 10.1038/npp.2008.142

[47]

Yoshida "Chronopharmacology of analgesic effect and its tolerance induced by morphine in mice" J. Pharmacol. Exp. Therap. (2003) 10.1124/jpet.103.049031

[48]

Yovell "Ultra-low-dose buprenorphine as a time-limited treatment for severe suicidal ideation: a randomized controlled trial" Am. J. Psychiatry (2015) 10.1176/appi.ajp.2015.15040535

Cited By

55

Contribution of the opioid system to depression and to the therapeutic effects of classical antidepressants and ketamine

Miroslav Adzic, Iva Lukic · 2023

Life Sciences

Naloxone exacerbates memory impairments and depressive-like behavior after mild traumatic brain injury (mTBI) in mice with upregulated opioid system activity

Anna Leśniak, Pawel Leszczynski · 2017

Behavioural Brain Research

Metrics

55

Citations

48

References

Details

Published: Feb 01, 2017
Vol/Issue: 319
Pages: 96-103
License: View

Authors

Funding

National Institutes of Health

Cite This Article

Shivon A. Robinson, Rebecca L. Erickson, Caroline A. Browne, et al. (2017). A role for the mu opioid receptor in the antidepressant effects of buprenorphine. Behavioural Brain Research, 319, 96-103. https://doi.org/10.1016/j.bbr.2016.10.050

A role for the mu opioid receptor in the antidepressant effects of buprenorphine

You May Also Like