Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms

Asta Zubrienė; Malgorzata Gutkowska; Jurgita Matulienė; Romanas Chaleckis; Vilma Michailovienė; Aliona Voroncova; Česlovas Venclovas; Alicja Zylicz; Maciej Zylicz; Daumantas Matulis

doi:10.1016/j.bpc.2010.09.003

journal article Nov 01, 2010

Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms

Asta Zubrienė Malgorzata Gutkowska Jurgita Matulienė Romanas Chaleckis Vilma Michailovienė Aliona Voroncova Česlovas Venclovas

Alicja Zylicz Maciej Zylicz Daumantas Matulis

Biophysical Chemistry Vol. 152 No. 1-3 pp. 153-163 · Elsevier BV

View at Publisher Save 10.1016/j.bpc.2010.09.003

Topics

No keywords indexed for this article. Browse by subject →

References

54

[1]

Taldone "Discovery and development of heat shock protein 90 inhibitors" Bioorg. Med. Chem. (2009) 10.1016/j.bmc.2008.10.087

[2]

Wandinger "The Hsp90 chaperone machinery" J. Biol. Chem. (2008) 10.1074/jbc.r800007200

[3]

Neckers "The complex dance of the molecular chaperone Hsp90" Trends Biochem. Sci. (2009) 10.1016/j.tibs.2009.01.006

[4]

Neckers "Visualizing the twists and turns of a molecular chaperone" Nat. Struct. Mol. Biol. (2009) 10.1038/nsmb0309-235

[5]

Mayer "The Hsp90 mosaic: a picture emerges" Nat. Struct. Mol. Biol. (2009) 10.1038/nsmb0109-2

[6]

Walerych "Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions" Oncogene (2009) 10.1038/onc.2009.281

[7]

Banz "Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta" Biochim. Biophys. Acta (2009) 10.1016/j.bbamcr.2009.08.002

[8]

van Montfort "Structure-based design of molecular cancer therapeutics" Trends Biotechnol. (2009) 10.1016/j.tibtech.2009.02.003

[9]

Sharp "In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors" Cancer Res. (2007) 10.1158/0008-5472.can-06-3473

[10]

Sgobba "Structure-based and in silico design of Hsp90 inhibitors" ChemMedChem (2009) 10.1002/cmdc.200900256

[11]

Zuehlke "Hsp90 and co-chaperones twist the functions of diverse client proteins" Biopolymers (2010) 10.1002/bip.21292

[12]

Fukuyo "Geldanamycin and its anti–cancer activities" Cancer Lett. (2009)

[13]

Delmotte "A new antifungal substance of fungal origin" Nature (1953) 10.1038/171344a0

[14]

Schulte "Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin" Cell Stress Chaperones (1998) 10.1379/1466-1268(1998)003<0100:arbttn>2.3.co;2

[15]

Roe "Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin" J. Med. Chem. (1999) 10.1021/jm980403y

[16]

Prodromou "Structural basis of the radicicol resistance displayed by a fungal Hsp90" ACS Chem. Biol. (2009) 10.1021/cb9000316

[17]

Nilapwar "Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90" J. Mol. Biol. (2009) 10.1016/j.jmb.2009.07.041

[18]

Velazquez Campoy "ITC in the post-genomic era...? Priceless" Biophys. Chem. (2005) 10.1016/j.bpc.2004.12.015

[19]

Velazquez-Campoy "Isothermal titration calorimetry" Curr. Protoc. Cell Biol. (2004) 10.1002/0471143030.cb1708s23

[20]

Freire "Isothermal titration calorimetry: controlling binding forces in lead optimization" Drug Discov. Today: Technologies (2004) 10.1016/j.ddtec.2004.11.016

[21]

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

Mei-Chu Lo, Ann Aulabaugh, Guixian Jin et al.

Analytical Biochemistry 2004 10.1016/j.ab.2004.04.031

[22]

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

Frank H Niesen, Helena Berglund, Masoud Vedadi

Nature Protocols 2007 10.1038/nprot.2007.321

[23]

High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery

Michael W. Pantoliano, Eugene C. Petrella, Joseph D. Kwasnoski et al.

SLAS Discovery 2001 10.1177/108705710100600609

[24]

Todd "Direct binding assays for pharma screening" Genetic Eng. News (2003)

[25]

Cimmperman "A quantitative model of thermal stabilization and destabilization of proteins by ligands" Biophys. J. (2008) 10.1529/biophysj.108.134973

[26]

Thermodynamic Stability of Carbonic Anhydrase: Measurements of Binding Affinity and Stoichiometry Using ThermoFluor

Daumantas Matulis, James K. Kranz, F. Raymond Salemme et al.

Biochemistry 2005 10.1021/bi048135v

[27]

Enhancing Recombinant Protein Quality and Yield by Protein Stability Profiling

Tara M. Mezzasalma, James K. Kranz, Winnie Chan et al.

SLAS Discovery 2007 10.1177/1087057106297984

[28]

Thermofluor-based high-throughput stability optimization of proteins for structural studies

Ulrika B. Ericsson, B. Martin Hallberg, George T. DeTitta et al.

Analytical Biochemistry 2006 10.1016/j.ab.2006.07.027

[29]

Krukenberg "Grp94, the endoplasmic reticulum Hsp90, has a similar solution conformation to cytosolic Hsp90 in the absence of nucleotide" Protein Sci. (2009) 10.1002/pro.191

[30]

Vaughan "A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s" FEBS J. (2009) 10.1111/j.1742-4658.2008.06773.x

[31]

Structure and Mechanism of the Hsp90 Molecular Chaperone Machinery

Laurence H. Pearl, Chrisostomos Prodromou

Annual Review of Biochemistry 2006 10.1146/annurev.biochem.75.103004.142738

[32]

Mickler "The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis" Nat. Struct. Mol. Biol. (2009) 10.1038/nsmb.1557

[33]

Hessling "Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90" Nat. Struct. Mol. Biol. (2009) 10.1038/nsmb.1565

[34]

Do enthalpy and entropy distinguish first in class from best in class?

Ernesto Freire

Drug Discovery Today 2008 10.1016/j.drudis.2008.07.005

[35]

Doyle "Tight binding affinities determined from thermodynamic linkage to protons by titration calorimetry" Methods Enzymol. (1995) 10.1016/0076-6879(95)59044-7

[36]

Christensen (1976)

[37]

Baker "Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry" Biophys. J. (1996) 10.1016/s0006-3495(96)79403-1

[38]

Baker "Dissecting the energetics of a protein–protein interaction: the binding of ovomucoid third domain to elastase" J. Mol. Biol. (1997) 10.1006/jmbi.1997.0977

[39]

Bradshaw "Calorimetric investigation of proton linkage by monitoring both the enthalpy and association constant of binding: application to the interaction of the Src SH2 domain with a high-affinity tyrosyl phosphopeptide" Biochemistry (1998) 10.1021/bi9814991

[40]

Zubriene "Measurement of nanomolar dissociation constants by titration calorimetry and thermal shift assay — radicicol binding to Hsp90 and ethoxzolamide binding to CAII" Int. J. Mol. Sci. (2009) 10.3390/ijms10062662

[41]

Anderson "Fluorescence polarization of the complexes of 1-anilino-8-naphthalenesulfonate with bovine serum albumin. Evidence for preferential orientation of the ligand" Biochemistry (1969) 10.1021/bi00829a051

[42]

Matulis "1-anilino-8-naphthalene sulfonate as a protein conformational tightening agent" Biopolymers (1999) 10.1002/(sici)1097-0282(199905)49:6<451::aid-bip3>3.0.co;2-6

[43]

Matulis "1-Anilino-8-naphthalene sulfonate anion-protein binding depends primarily on ion pair formation" Biophys. J. (1998) 10.1016/s0006-3495(98)77799-9

[44]

Zurawska "Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo" Biochim. Biophys. Acta (2010) 10.1016/j.bbamcr.2010.03.002

[45]

Dehner "NMR chemical shift perturbation study of the N-terminal domain of Hsp90 upon binding of ADP, AMP-PNP, geldanamycin, and radicicol" Chembiochem (2003) 10.1002/cbic.200300658

[46]

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues

Lata T. Gooljarsingh, Christine Fernandes, Kang Yan et al.

Proceedings of the National Academy of Sciences 2006 10.1073/pnas.0602650103

[47]

Nakamura "Isothermal acid-titration calorimetry for evaluating the pH dependence of protein stability" Biophys. Chem. (2004) 10.1016/j.bpc.2003.11.006

[48]

Baranauskiene "Determination of the thermodynamics of carbonic anhydrase acid-unfolding by titration calorimetry" J. Biochem. Biophys. Methods (2008) 10.1016/j.jprot.2007.12.003

[49]

A graph‐theory algorithm for rapid protein side‐chain prediction

Adrian A. Canutescu, Andrew A. Shelenkov, Roland L. Dunbrack

Protein Science 2003 10.1110/ps.03154503

[50]

Sigg (1969)

Showing 50 of 54 references

Metrics

21

Citations

54

References

Details

Published: Nov 01, 2010
Vol/Issue: 152(1-3)
Pages: 153-163
License: View

Authors

Institute of Biotechnology Life Sciences Center Vilnius University, Saulėtekio 7, Vilnius, Lithuania

Johnson & Johnson Pharmaceutical Research & Development, LLC, Eagleview Corporate Center, 665 Stockton Drive, Suite 104, Exton, Pennsylvania 19341

Cite This Article

Asta Zubrienė, Malgorzata Gutkowska, Jurgita Matulienė, et al. (2010). Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms. Biophysical Chemistry, 152(1-3), 153-163. https://doi.org/10.1016/j.bpc.2010.09.003

Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms

You May Also Like