journal article Open Access Dec 01, 2016

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

Cancer Cell Vol. 30 No. 6 pp. 836-848 · Elsevier BV
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References
137
[1]
Abusamra "Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis" Blood Cell Mol. Dis. (2005) 10.1016/j.bcmd.2005.07.001
[2]
Adachi "Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma" Oncotarget (2016) 10.18632/oncotarget.12221
[3]
Admyre "B cell-derived exosomes can present allergen peptides and activate allergen-specific T cells to proliferate and produce TH2-like cytokines" J. Allergy Clin. Immunol. (2007) 10.1016/j.jaci.2007.06.040
[4]
Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

Khalid Al-Nedawi, Brian Meehan, Johann Micallef et al.

Nature Cell Biology 2008 10.1038/ncb1725
[5]
Alegre "Study of circulating microRNA-125b levels in serum exosomes in advanced melanoma" Arch. Pathol. Lab. Med. (2014) 10.5858/arpa.2013-0134-oa
[6]
Alegre "Circulating melanoma exosomes as diagnostic and prognosis biomarkers" Clin. Chim. Acta (2016) 10.1016/j.cca.2015.12.031
[7]
Alvarez-Erviti "Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes" Nat. Biotechnol. (2011) 10.1038/nbt.1807
[8]
Atay "Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells" Exp. Cell Res. (2011) 10.1016/j.yexcr.2011.01.014
[9]
Atay "Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion" Proc. Natl. Acad. Sci. USA (2014) 10.1073/pnas.1310501111
[10]
Au Yeung "Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1" Nat. Commun. (2016) 10.1038/ncomms11150
[11]
Azmi "Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review" Cancer Metastasis Rev. (2013) 10.1007/s10555-013-9441-9
[12]
Baer "Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches" Exp. Cell Res. (2013) 10.1016/j.yexcr.2013.03.026
[13]
Balaj "Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences" Nat. Commun. (2011) 10.1038/ncomms1180
[14]
Benito-Martin "The new deal: a potential role for secreted vesicles in innate immunity and tumor progression" Front. Immunol. (2015) 10.3389/fimmu.2015.00066
[15]
Besse "Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC" Oncoimmunology (2016) 10.1080/2162402x.2015.1071008
[16]
Bhatnagar "Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo" Blood (2007) 10.1182/blood-2007-03-079152
[17]
Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

Angélique Bobrie, Sophie Krumeich, Fabien Reyal et al.

Cancer Research 2012 10.1158/0008-5472.can-12-0925
[18]
Boelens "Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways" Cell (2014) 10.1016/j.cell.2014.09.051
[19]
Boukouris "Exosomes in bodily fluids are a highly stable resource of disease biomarkers" Proteomics Clin. Appl. (2015) 10.1002/prca.201400114
[20]
Bryant "Changes in circulating microRNA levels associated with prostate cancer" Br. J. Cancer (2012) 10.1038/bjc.2011.595
[21]
Chalmin "Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells" J. Clin. Invest. (2010)
[22]
Chen "Efficient induction of antitumor T cell immunity by exosomes derived from heat-shocked lymphoma cells" Eur. J. Immunol. (2006) 10.1002/eji.200535501
[23]
Chen "Exosomes from drug-resistant breast cancer cells transmit chemoresistance by a horizontal transfer of microRNAs" PLoS One (2014) 10.1371/journal.pone.0095240
[24]
Chevillet "Quantitative and stoichiometric analysis of the microRNA content of exosomes" Proc. Natl. Acad. Sci. USA (2014) 10.1073/pnas.1408301111
[25]
Cho "Exosomes from breast cancer cells can convert adipose tissue-derived mesenchymal stem cells into myofibroblast-like cells" Int. J. Oncol. (2012)
[26]
Chow "Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-kappaB" Sci. Rep. (2014) 10.1038/srep05750
[27]
Ciardiello "Focus on extracellular vesicles: new frontiers of cell-to-cell communication in cancer" Int. J. Mol. Sci. (2016) 10.3390/ijms17020175
[28]
Colombo "Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles" Annu. Rev. Cell Dev. Biol. (2014) 10.1146/annurev-cellbio-101512-122326
[29]
Costa-Silva "Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver" Nat. Cell Biol. (2015) 10.1038/ncb3169
[30]
De Toro "Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications" Front. Immunol. (2015) 10.3389/fimmu.2015.00203
[31]
De Wever "Stromal myofibroblasts are drivers of invasive cancer growth" Int. J. Cancer (2008) 10.1002/ijc.23925
[32]
Di Vizio "Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease" Am. J. Pathol. (2012) 10.1016/j.ajpath.2012.07.030
[33]
Eldh "MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma" BMC Cancer (2014) 10.1186/1471-2407-14-962
[34]
Escudier "Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of the first phase I clinical trial" J. Trans. Med. (2005) 10.1186/1479-5876-3-10
[35]
Falati "Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin" J. Exp. Med. (2003) 10.1084/jem.20021868
[36]
Federici "Exosome release and low pH belong to a framework of resistance of human melanoma cells to cisplatin" PLoS One (2014) 10.1371/journal.pone.0088193
[37]
Finger "Hypoxia, inflammation, and the tumor microenvironment in metastatic disease" Cancer Metastasis Rev. (2010) 10.1007/s10555-010-9224-5
[38]
Fong "Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis" Nat. Cell Biol. (2015) 10.1038/ncb3094
[39]
Fridlender "Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN" Cancer Cell (2009) 10.1016/j.ccr.2009.06.017
[40]
Myeloid-derived suppressor cells as regulators of the immune system

Dmitry I. Gabrilovich, Srinivas Nagaraj

Nature Reviews Immunology 2009 10.1038/nri2506
[41]
Galindo-Hernandez "Extracellular vesicles from MDA-MB-231 breast cancer cells stimulated with linoleic acid promote an EMT-like process in MCF10A cells" Prostaglandins Leukot. Essent. Fatty Acids (2014) 10.1016/j.plefa.2014.09.002
[42]
Gan "The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered" FEBS J. (2013) 10.1111/febs.12393
[43]
Gradilla "Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion" Nat. Commun. (2014) 10.1038/ncomms6649
[44]
Grange "Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche" Cancer Res. (2011) 10.1158/0008-5472.can-11-0241
[45]
Harding "Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes" J. Cell Biol. (1983) 10.1083/jcb.97.2.329
[46]
He "Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs" Carcinogenesis (2015) 10.1093/carcin/bgv081
[47]
Headley "Visualization of immediate immune responses to pioneer metastatic cells in the lung" Nature (2016) 10.1038/nature16985
[48]
Hedlund "Human placenta expresses and secretes NKG2D ligands via exosomes that down-modulate the cognate receptor expression: evidence for immunosuppressive function" J. Immunol. (2009) 10.4049/jimmunol.0803477
[49]
Hendrix "Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis" J. Natl. Cancer Inst. (2010) 10.1093/jnci/djq153
[50]
Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

Joshua L. Hood, Roman Susana San, Samuel A. Wickline

Cancer Research 2011 10.1158/0008-5472.can-10-4455

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Details
Published
Dec 01, 2016
Vol/Issue
30(6)
Pages
836-848
License
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Funding
National Cancer Institute Award: CA169416
National Institutes of Health Award: T32GM007739
National Institute of General Medical Sciences
Worldwide Cancer Research
Ministerio de Economía y Competitividad Award: SAF2014-54541-R
U.S. Department of Defense Award: W81XWH-13-1-0249
AXA Research Fund
Yonsei University College of Medicine
Fundação Champalimaud
Children's Cancer and Blood Foundation
Fundación Josep Carreras Contra la Leucemia
Cite This Article
Annette Becker, Basant Kumar Thakur, Joshua Mitchell Weiss, et al. (2016). Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis. Cancer Cell, 30(6), 836-848. https://doi.org/10.1016/j.ccell.2016.10.009