TAF1D promotes tumorigenesis and metastasis by activating PI3K/AKT/mTOR signaling in clear cell renal cell carcinoma

Rodriguez Peñaranda "Artificial intelligence in surgical training for kidney cancer: a systematic review of the literature" Diagnostics (2023) 10.3390/diagnostics13193070

[3]

Hao "Stereotactic body radiation therapy to the kidney for metastatic renal cell carcinoma: a narrative review of an emerging concept" Cancer Treat. Res. Commun. (2023)

[4]

Li "Facile synthesis of MoS2@red phosphorus heterojunction for synergistically photodynamic and photothermal therapy of renal cell carcinoma" Colloids Surf. B: Biointerfaces (2024) 10.1016/j.colsurfb.2024.114031

[5]

Gorski "A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription" EMBO J. (2007) 10.1038/sj.emboj.7601601

[6]

Zomerdijk "Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits" Science (New York, N.Y.) (1994) 10.1126/science.7801130

[7]

Watt "RNA polymerases I and III in development and disease" Semin. Cell Dev. Biol. (2023) 10.1016/j.semcdb.2022.03.027

[8]

Zhang "TAF1D promotes proliferation by transcriptionally activating G2/M phase-related genes in MYCN-amplified neuroblastoma" Cancer Sci. (2023) 10.1111/cas.15815

[9]

TAF1D Functions as a Novel Biomarker in Osteosarcoma

Yu-Nan Man, Yu Sun, Pei-Jun Chen et al.

Journal of Cancer 2023 10.7150/jca.85688

[10]

Wang "A novel nuclear protein, MGC5306 interacts with DNA polymerase beta and has a potential role in cellular phenotype" Cancer Res. (2004) 10.1158/0008-5472.can-04-2801

[11]

Motzer "NCCN guidelines® insights: kidney cancer, version 2.2024: featured updates to the NCCN guidelines" J. Natl. Compr. Cancer Netw. (2024) 10.6004/jnccn.2024.0008

[12]

Molina "Sunitinib objective response in metastatic renal cell carcinoma: analysis of 1059 patients treated on clinical trials" Eur. J. Cancer (Oxford, England : 1990) (2014) 10.1016/j.ejca.2013.08.021

[13]

Yu "STIL promotes tumorigenesis of bladder cancer by activating PI3K/AKT/mTOR signaling pathway and targeting C-Myc" Cancers (2022) 10.3390/cancers14235777

[14]

Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT

Renjie Zhang, Zijian Wang, Wenjie You et al.

Cancer Cell International 2020 10.1186/s12935-020-01607-y

[15]

Liu "Hypoxia-induced PLOD2 promotes clear cell renal cell carcinoma progression via modulating EGFR-dependent AKT pathway activation" Cell Death Dis. (2023) 10.1038/s41419-023-06298-7

[16]

EMT: 2016

M. Angela Nieto, Ruby Yun-Ju Huang, Rebecca A. Jackson et al.

Cell 2016 10.1016/j.cell.2016.06.028

[17]

Clear cell renal cell carcinoma ontogeny and mechanisms of lethality

Eric Jonasch, Cheryl Lyn Walker, W. Kimryn Rathmell

Nature Reviews Nephrology 2021 10.1038/s41581-020-00359-2

[18]

Atkins "Current and emerging therapies for first-line treatment of metastatic clear cell renal cell carcinoma" Cancer Treat. Rev. (2018) 10.1016/j.ctrv.2018.07.009

[19]

Gui "A new thinking: extended application of genomic selection to screen multiomics data for development of novel hypoxia-immune biomarkers and target therapy of clear cell renal cell carcinoma" Brief. Bioinform. (2021) 10.1093/bib/bbab173

[20]

Hume "A unified model for the G1/S cell cycle transition" Nucleic Acids Res. (2020) 10.1093/nar/gkaa1002

[21]

Peng "AGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway" BMC Cancer (2023) 10.1186/s12885-022-10466-x

[22]

Liu "Jaceosidin induces apoptosis and inhibits migration in AGS gastric cancer cells by regulating ROS-mediated signaling pathways" Redox Rep. (2024) 10.1080/13510002.2024.2313366

[23]

Song "DMC-siERCC2 hybrid nanoparticle enhances TRAIL sensitivity by inducing cell cycle arrest for glioblastoma treatment" Biomed. Pharmacother. (2024) 10.1016/j.biopha.2024.116470

[24]

Malumbres "Cell cycle, CDKs and cancer: a changing paradigm" Nat. Rev. Cancer (2009) 10.1038/nrc2602

[25]

Li "USP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer" Cell Death Dis. (2024) 10.1038/s41419-024-06446-7

[26]

Lu "Role of the mammalian target of rapamycin pathway in liver cancer: from molecular genetics to targeted therapies" Hepatology (Baltimore, Md) (2021) 10.1002/hep.31310

[27]

Song "AKT as a therapeutic target for cancer" Cancer Res. (2019) 10.1158/0008-5472.can-18-2738

[28]

O’Donnell "PI3K-AKT-mTOR inhibition in cancer immunotherapy, redux" Semin. Cancer Biol. (2018) 10.1016/j.semcancer.2017.04.015

[29]

Hu "Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways" J. Exp. Clin. Cancer Res. (2020) 10.1186/s13046-020-01578-y

[30]

Zhang "Artesunate promotes the proliferation of neural stem/progenitor cells and alleviates ischemia-reperfusion injury through PI3K/Akt/FOXO-3a/p27(kip1) signaling pathway" Aging (2020) 10.18632/aging.103121

[31]

Comprehensive molecular characterization of clear cell renal cell carcinoma

Nature 2013 10.1038/nature12222

[32]

Sato "Integrated molecular analysis of clear-cell renal cell carcinoma" Nat. Genet. (2013) 10.1038/ng.2699

[33]

Zhang "Targeting the Wnt/β-catenin signaling pathway in cancer" J. Hematol. Oncol. (2020) 10.1186/s13045-020-00990-3

[34]

Shang "The regulation of β-catenin activity and function in cancer: therapeutic opportunities" Oncotarget (2017) 10.18632/oncotarget.15687

[35]

Tai "Targeting the WNT signaling pathway in cancer therapeutics" Oncologist (2015) 10.1634/theoncologist.2015-0057

[36]

Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

Hui Zhao, Tianqi Ming, Shun Tang et al.

Molecular Cancer 2022 10.1186/s12943-022-01616-7

[37]

Zhu "LiCl promotes recovery of radiation-induced oral mucositis and dysgeusia" J. Dent. Res. (2021) 10.1177/0022034521994756

[38]

Li "Epigenetic alterations in renal cell cancer with TKIs resistance: from mechanisms to clinical applications" Front. Genet. (2020)

[39]

Peng "NT5E inhibition suppresses the growth of sunitinib-resistant cells and EMT course and AKT/GSK-3β signaling pathway in renal cell cancer" IUBMB Life (2019) 10.1002/iub.1942

[40]

Sekino "PTEN is involved in sunitinib and sorafenib resistance in renal cell carcinoma" Anticancer Res. (2020) 10.21873/anticanres.14149

[41]

Xiong "RRM2 regulates sensitivity to sunitinib and PD-1 blockade in renal cancer by stabilizing ANXA1 and activating the AKT pathway" Adv. Sci. (Weinheim, Baden-Wurttemberg, Germany) (2021)

[42]

Xu "Single-cell RNA-sequencing analysis reveals MYH9 promotes renal cell carcinoma development and sunitinib resistance via AKT signaling pathway" Cell Death Dis. (2022) 10.1038/s41420-022-00933-6

[43]

Teng "Effector mechanisms of sunitinib-induced G1 cell cycle arrest, differentiation, and apoptosis in human acute myeloid leukaemia HL60 and KG-1 cells" Ann. Hematol. (2013) 10.1007/s00277-012-1627-7

[44]

D’Costa "Y-box binding protein-1 is crucial in acquired drug resistance development in metastatic clear-cell renal cell carcinoma" J. Exp. Clin. Cancer Res. (2020) 10.1186/s13046-020-1527-y

[45]

Srimongkol "Sunitinib efficacy with minimal toxicity in patient-derived retinoblastoma organoids" J. Exp. Clin. Cancer Res. (2023) 10.1186/s13046-023-02608-1

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Details

Published: Dec 01, 2024
Vol/Issue: 124
Pages: 111425
License: View

Authors

Nanjing University

Xihua University

Institute of Photovoltaic Southwest Petroleum University Chengdu 610500 China

F

Feng Tang

Beijing Computational Science Research Center, Beijing 100193, People’s Republic of China

Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China

Z

Zhonghua Yang

Cite This Article

Xuan Hu, Liang Chen, Tao Liu, et al. (2024). TAF1D promotes tumorigenesis and metastasis by activating PI3K/AKT/mTOR signaling in clear cell renal cell carcinoma. Cellular Signalling, 124, 111425. https://doi.org/10.1016/j.cellsig.2024.111425

TAF1D promotes tumorigenesis and metastasis by activating PI3K/AKT/mTOR signaling in clear cell renal cell carcinoma

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