journal article Open Access Sep 25, 2017

Viable Osteochondral Allograft for the Treatment of a Full‐Thickness Cartilage Defect of the Patella

View at Publisher Save 10.1016/j.eats.2017.06.034
Abstract
Abstract


Isolated cartilage defects can lead to significant pain and disability, prompting the development of a number of options for restorative treatment. Each method has advantages and limitations, and no single technique has gained widespread use. We present a technique for implantation of a cryopreserved osteochondral allograft (Cartiform) for the treatment of full‐thickness cartilage defects. Cartiform is a cryopreserved osteochondral allograft composed of chondrocytes, chondrogenic growth factors, and extracellular matrix proteins. This implant allows for regenerative treatment of full‐thickness cartilage lesions in a single surgical procedure.


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References
17
[2]
KrychAJ PareekA KingAH JohnsonNR Stuart MJ Williams RJ 3rd.Return to sport after the surgical management of articular cartilage lesions in the knee: A meta‐analysis.Knee Surg Sports Traumatol ArthroscAugust 18 2016. [Epub ahead of print.] 10.1007/s00167-016-4262-3
[10]
Osiris Therapeutics I.Characterization of Cartiform® viable osteochondral allograft. Cartiform White Paper 2015.
[11]
Osiris Therapeutics I.Cartiform® retains endogenous viable cells after two years storage at –80°C. Cartiform White Paper 2015.
[12]
Osiris Therapeutics I.Cartiform promotes mesenchymal stem cell migration and chondrogenesis. Cartiform White Paper 2015.
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