The use of complementary and traditional medicine for the treatment of patients with COVID-19: A systematic review

Bárbara Badanta; Marta Alonso García; Ángela Estepa Jiménez; Giancarlo Lucchetti; Rocío de Diego-Cordero

doi:10.1016/j.explore.2023.02.005

journal article Sep 01, 2023

The use of complementary and traditional medicine for the treatment of patients with COVID-19: A systematic review

Bárbara Badanta Marta Alonso García Ángela Estepa Jiménez Giancarlo Lucchetti

Rocío de Diego-Cordero

EXPLORE Vol. 19 No. 5 pp. 646-662 · Elsevier BV

View at Publisher Save 10.1016/j.explore.2023.02.005

Topics

No keywords indexed for this article. Browse by subject →

References

68

[1]

Berekaa "Insights into the COVID-19 pandemic: origin, pathogenesis, diagnosis, and therapeutic interventions" (2021)

[2]

World Health Organisation (WHO). COVID-19 situation report as of 11th march 2020. (n.d.) Retrieved from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200311-sitrep-51-covid-19.pdf?sfvrsn=1ba62e57_10.

[3]

Chakraborty "SARS-CoV-2 causing pneumonia-associated respiratory disorder (COVID-19): diagnostic and proposed therapeutic options" Eur Rev Med Pharmacol Sci (2020)

[4]

Díaz "Pharmacological treatment of COVID-19: narrative review of the working group in infectious diseases and sepsis (GTEIS) and the working groups in transfusions and blood products (GTTH)" Med Intens (2020)

[5]

Dragojevic Simic "An Overview of antiviral strategies for coronavirus 2 (SARS-CoV-2) infection with special reference to antimalarial drugs chloroquine and hydroxychloroquine" Int J Clin Pract (2020)

[6]

Gavriatopoulou "Emerging treatment strategies for COVID-19 infection" Clin Exp Med (2021) 10.1007/s10238-020-00671-y

[7]

Liu "COVID-19: progress in diagnostics, therapy and vaccination" Theranostics (2020) 10.7150/thno.47987

[8]

Asselah "COVID-19: discovery, diagnostics and drug development" J Hepatol (2021) 10.1016/j.jhep.2020.09.031

[9]

Balkhair "Anakinra in hospitalized patients with severe COVID-19 pneumonia requiring oxygen therapy: results of a prospective, open-label, interventional study" Int J Infect Dis (2021) 10.1016/j.ijid.2020.11.149

[10]

Franzetti "IL-1 receptor antagonist anakinra in the treatment of COVID-19 acute respiratory distress syndrome: a retrospective, observational study" J Immunol (2021) 10.4049/jimmunol.2001126

[11]

Anakinra for patients with COVID-19: a meta-analysis of non-randomized cohort studies.

Laura Pasin, Giulio Cavalli, Paolo Navalesi et al.

European Journal of Internal Medicine 2021 10.1016/j.ejim.2021.01.016

[12]

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results

New England Journal of Medicine 2021 10.1056/nejmoa2023184

[13]

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

Lindsey R. Baden, Hana M. El Sahly, Brandon Essink et al.

New England Journal of Medicine 2021 10.1056/nejmoa2035389

[14]

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

Fernando P. Polack, Stephen J. Thomas, Nicholas Kitchin et al.

New England Journal of Medicine 2020 10.1056/nejmoa2034577

[15]

WHO (2021). COVID vaccines: widening inequality and millions vulnerable. https://news.un.org/en/story/2021/09/1100192.

[16]

Kreps "The Relationship between US Adults’ Misconceptions about COVID-19 Vaccines and Vaccination Preferences" Vaccines (Basel) (2021) 10.3390/vaccines9080901

[17]

Fokunang "Traditional medicine: past, present and future research and development prospects and integration in the National Health System of Cameroon. African journal of traditional, complementary, and alternative medicines" AJTCAM (2011) 10.4314/ajtcam.v8i3.65276

[18]

De Sousa "Traditional complementary and integrative medicine: challenges in constructing an evaluation model of care" Cienc Saude Colet (2018)

[19]

Xiong "Chinese herbal medicine for coronavirus disease 2019: a systematic review and meta-analysis" (2020)

[20]

Luo "Can chinese medicine be used for prevention of corona virus disease 2019 (COVID-19)? A review of historical classics, research evidence and current prevention programs" Chin J Integr Med (2020) 10.1007/s11655-020-3192-6

[21]

He "Discussion on the effect pathways of preventing and treating coronavirus disease 2019 by acupuncture and moxibustion from the regulation of immune inflammatory response" Zhong guo Zhen Jiu (2020)

[22]

Góngora Gómez "La Medicina Tradicional China en el tratamiento de la COVID-19" Rev Int Acupunt (2020)

[23]

Yang "Traditional Chinese medicine in the treatment of patients infected with 2019-new coronavirus (SARS-CoV-2): a review and perspective" Int J Biol Sci (2020) 10.7150/ijbs.45538

[24]

Page "The PRISMA 2020 statement: an updated guideline for reporting systematic reviews" BMJ (2021)

[25]

Braun "Thematic analysis" (2019)

[26]

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies

Erik von Elm, Douglas G Altman, Matthias Egger et al.

The Lancet 2007 10.1016/s0140-6736(07)61602-x

[27]

Boutron "Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration" Ann Intern Med (2008) 10.7326/0003-4819-148-4-200802190-00008

[28]

An B. Yuan "Clinical characteristics and impacts of traditional Chinese medicine treatment on the convalescents of COVID-19" Int J Med Sci (2021) 10.7150/ijms.52664

[29]

Guo "Xuebijing injection in the treatment of COVID-19: a retrospective case-control study" Ann Palliat Med (2020) 10.21037/apm-20-1478

[30]

Hu "He-Jie-Shen-Shi decoction as an adjuvant therapy on severe coronavirus disease 2019: a retrospective cohort and potential mechanistic study" Front Pharmacol (2021) 10.3389/fphar.2021.700498

[31]

Liu "Arbidol combined with the Chinese medicine Lianhuaqingwen capsule versus arbidol alone in the treatment of COVID-19" Medicine (Baltimore) (2021) 10.1097/md.0000000000024475

[32]

Ni "Effects of Shuanghuanglian oral liquids on patients with COVID-19: a randomized, open-label, parallel-controlled, multicenter clinical trial" Front Med (2021) 10.1007/s11684-021-0853-6

[33]

Hu "Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: a multicenter, prospective, randomized controlled trial" Phytomed: Int J Phytother Phytopharmacol (2021) 10.1016/j.phymed.2020.153242

[34]

Efficacy and safety assessment of severe COVID-19 patients with Chinese medicine: A retrospective case series study at early stage of the COVID-19 epidemic in Wuhan, China

Yan Wang, Cheng Lu, Hao Li et al.

Journal of Ethnopharmacology 2021 10.1016/j.jep.2021.113888

[35]

Efficacy and safety of Xiyanping injection in the treatment of COVID‐19: A multicenter, prospective, open‐label and randomized controlled trial

Xin‐Yi Zhang, Lang Lv, Yu‐Long Zhou et al.

Phytotherapy Research 2021 10.1002/ptr.7141

[36]

Zhang "Effects of Tanreqing Capsule on the negative conversion time of nucleic acid in patients with COVID-19: a retrospective cohort study" J Integr Med (2021) 10.1016/j.joim.2020.10.002

[37]

Chen "Clinical evaluation of Shufeng Jiedu capsules combined with umifenovir (Arbidol) in the treatment of common-type COVID-19: a retrospective study" Expert Rev Respir Med (2021) 10.1080/17476348.2020.1822741

[38]

Ma "Efficacy and safety of ReDuNing injection as a treatment for COVID-19 and its inhibitory effect against SARS-CoV-2" J Ethnopharmacol (2021) 10.1016/j.jep.2021.114367

[39]

Shi "Efficacy and safety of Chinese herbal medicine versus Lopinavir-Ritonavir in adult patients with coronavirus disease 2019: a non-randomized controlled trial" Phytomedicine (2021) 10.1016/j.phymed.2020.153367

[40]

Xu "Efficacy and safety of Reduning injection in the treatment of COVID-19: a randomized, multicenter clinical study" Ann Palliat Med (2021) 10.21037/apm-20-2121

[41]

Liu "Yindan Jiedu Granules, a traditional Chinese medicinal formulation, as a potential treatment for coronavirus disease 2019" Front Pharmacol (2021) 10.3389/fphar.2020.634266

[42]

Wang "Effect and safety of Chinese herbal medicine granules in patients with severe coronavirus disease 2019 in Wuhan, China: a retrospective, single-center study with propensity score matching" Phytomedicine (2021) 10.1016/j.phymed.2020.153404

[43]

Zhang "Evaluation of the adjuvant efficacy of natural herbal medicine on COVID-19: a retrospective matched case-control study" Am J Chin Med (Gard City N Y) (2020) 10.1142/s0192415x20500391

[44]

Liu "Combination of Hua Shi Bai Du granule (Q-14) and standard care in the treatment of patients with coronavirus disease 2019 (COVID-19): a single-center, open-label, randomized controlled trial" Phytomedicine (2021) 10.1016/j.phymed.2021.153671

[45]

Zeng "Therapeutic effects of traditional Chinese medicine (Maxingshigan-Weijing Decoction) on COVID-19: an open-label randomized controlled trial" Integrative Medicine Research., (2021) 10.1016/j.imr.2021.100782

[46]

Li "Effects of Chinese medicine on symptoms, syndrome evolution, and lung inflammation absorption in COVID-19 convalescent patients during 84-day follow-up after hospital discharge: a prospective cohort and nested case-control study" Chin J Integr Med (2021) 10.1007/s11655-021-3328-3

[47]

Zhou "Traditional Chinese medicine shenhuang granule in patients with severe/critical COVID-19: a randomized controlled multicenter trial" Phytomedicine (2021) 10.1016/j.phymed.2021.153612

[48]

Shen "Positive effects of Lianhuaqingwen granules in COVID-19 patients: a retrospective study of 248 cases" Journal of Ethnopharmacology., (2021) 10.1016/j.jep.2021.114220

[49]

Feng "Clinical effect of traditional Chinese medicine Shenhuang granule in critically ill patients with COVID-19: a single-centered, retrospective, observational study" J. Microbiol. Biotechnol. (2021) 10.4014/jmb.2009.09029

[50]

Liu "Efficacy of Qingfei Paidu Decoction on Patients with COVID-19 Pneumonia in Wuhan, China: a Propensity Score Matching Study" Evid-Based Complement Altern Med (2021)

Showing 50 of 68 references

Cited By

12

A Triple-blind randomized controlled trial on the effects of turmeric versus ginger on inflammatory biomarkers in patients with COVID-19

Zahra Saleh, Mohammad Reza Asgari · 2025

Scientific Reports

Metrics

12

Citations

68

References

Details

Published: Sep 01, 2023
Vol/Issue: 19(5)
Pages: 646-662
License: View

Authors

B

Bárbara Badanta

Department of Nursing , Faculty of Nursing, Physiotherapy, and Podiatry, University of Seville, Seville, Spain

M

Marta Alonso García

�

Ángela Estepa Jiménez

G

Giancarlo Lucchetti

R

Rocío de Diego-Cordero

Faculty of Nursing, Physiotherapy, and Podiatry, University of Seville, Seville, Spain

Cite This Article

Bárbara Badanta, Marta Alonso García, Ángela Estepa Jiménez, et al. (2023). The use of complementary and traditional medicine for the treatment of patients with COVID-19: A systematic review. EXPLORE, 19(5), 646-662. https://doi.org/10.1016/j.explore.2023.02.005

The use of complementary and traditional medicine for the treatment of patients with COVID-19: A systematic review

You May Also Like