Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats

Meng Zhang; Licheng Yang; Maomao Zhu; Bing Yang; Yanjun Yang; Xiaobin Jia; Liang Feng

doi:10.1016/j.ijbiomac.2022.03.077

journal article May 01, 2022

Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats

Meng Zhang

Licheng Yang Maomao Zhu Bing Yang

Yanjun Yang

Xiaobin Jia Liang Feng

International Journal of Biological Macromolecules Vol. 206 pp. 849-860 · Elsevier BV

View at Publisher Save 10.1016/j.ijbiomac.2022.03.077

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References

63

[1]

Afkarian "Kidney disease and increased mortality risk in type 2 diabetes" J. Am. Soc. Nephrol. (2013) 10.1681/asn.2012070718

[2]

Gregg "Changes in diabetes-related complications in the United States, 1990–2010" N. Engl. J. Med. (2014) 10.1056/nejmoa1310799

[3]

Coemans "Occurrence of diabetic nephropathy after renal transplantation despite intensive glycemic control: an observational cohort study" Diabetes Care (2019) 10.2337/dc18-1936

[4]

Tang "Clinical efficacies, underlying mechanisms and molecular targets of chinese medicines for diabetic nephropathy treatment and management" Acta Pharm. Sin. B (2021) 10.1016/j.apsb.2020.12.020

[5]

Zheng "Polysaccharides from chinese herbal medicine for anti-diabetes recent advances" Int. J. Biol. Macromol. (2019) 10.1016/j.ijbiomac.2018.10.072

[6]

Wu "Mechanisms underlying the effect of polysaccharides in the treatment of type 2 diabetes: a review" Carbohydr. Polym. (2016) 10.1016/j.carbpol.2016.02.040

[7]

Wu "The role of the gut microbiome and its metabolites in metabolic diseases" Protein Cell (2021) 10.1007/s13238-020-00814-7

[8]

Fang "Roles of gut microbial metabolites in diabetic kidney disease" Front. Endocrinol. (2021) 10.3389/fendo.2021.636175

[9]

Mosterd "Intestinal microbiota and diabetic kidney diseases: the role of microbiota and derived metabolites inmodulation of renal inflammation and disease progression" Best Pract. Res. Clin. Endocrinol. Metab. (2021) 10.1016/j.beem.2021.101484

[10]

Chen "Microbiome-metabolome reveals the contribution of gut-kidney axis on kidney disease" J. Transl. Med. (2019) 10.1186/s12967-018-1756-4

[11]

Yang "Cordyceps cicadae polysaccharides ameliorated renal interstitial fibrosis in diabetic nephropathy rats by repressing inflammation and modulating gut microbiota dysbiosis" Int. J. Biol. Macromol. (2020) 10.1016/j.ijbiomac.2020.06.153

[12]

Zhang "Paeonol ameliorates diabetic renal fibrosis through promoting the activation of the Nrf2/ARE pathway via up-regulating Sirt1" Front. Pharmacol. (2018) 10.3389/fphar.2018.00512

[13]

Lau "Pharmacological investigations of the anti-diabetic effect of cortex moutan and its active component paeonol" Phytomedicine (2007) 10.1016/j.phymed.2007.01.007

[14]

Zhang "The attenuation of moutan cortex on oxidative stress for renal injury in AGEs-induced mesangial cell dysfunction and streptozotocin-induced diabetic nephropathy rats" Oxidative Med. Cell. Longev. (2014) 10.1155/2014/463815

[15]

Chen "Terpene glycoside component from moutan cortex ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-related inflammatory responses" J. Ethnopharmacol. (2016) 10.1016/j.jep.2016.09.043

[16]

Lian "Characterization of a novel polysaccharide from moutan cortex and its ameliorative effect on AGEs-induced diabetic nephropathy" Int. J. Biol. Macromol. (2021) 10.1016/j.ijbiomac.2021.02.062

[17]

DeFronzo "Pathophysiology of diabetic kidney disease: impact of SGLT2 inhibitors" Nat. Rev. Nephrol. (2021) 10.1038/s41581-021-00393-8

[18]

Abdel-Latif "Low-dose lixisenatide protects against early-onset nephropathy induced in diabetic rats" Life Sci. (2020) 10.1016/j.lfs.2020.118592

[19]

Wang "Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model" Diabetes (2010) 10.2337/db10-0019

[20]

Oraby "Dapagliflozin attenuates early markers of diabetic nephropathy in fructose-streptozotocin-induced diabetes in rats" Biomed. Pharmacother. (2019) 10.1016/j.biopha.2018.10.100

[21]

D.J. Berg N. Davidson R. Kühn W. Müller S. Menon G. Holland L. Thompson-Snipes M.W. Leach D. Rennick , Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses, J. Clin. Invest. 98 (4) 1010-1020. 10.1172/jci118861

[22]

Adaptive linear step-up procedures that control the false discovery rate

Yoav Benjamini, Abba M. Krieger, Daniel Yekutieli

Biometrika 2006 10.1093/biomet/93.3.491

[23]

Al Hroob "Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy" Biomed. Pharmacother. (2018) 10.1016/j.biopha.2018.06.148

[24]

Jefferson "Proteinuria in diabetic kidney disease: a mechanistic viewpoint" Kidney Int. (2008) 10.1038/ki.2008.128

[25]

Stratton "Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study" BMJ (2000) 10.1136/bmj.321.7258.405

[26]

Shulman "Cellular mechanisms of insulin resistance" J. Clin. Invest. (2000) 10.1172/jci10583

[27]

Egan "GLP-1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells" Diabetes Metab. Res. Rev. (2003) 10.1002/dmrr.357

[28]

Caramori "Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients: an indicator of more advanced glomerular lesions" Diabetes (2003) 10.2337/diabetes.52.4.1036

[29]

Zeng "The structures and biological functions of polysaccharides from traditional chinese herbs" Prog. Mol. Biol. Transl. Sci. (2019) 10.1016/bs.pmbts.2019.03.003

[30]

Xie "Anti-hypertensive and cardioprotective activities of traditional chinese medicine-derived polysaccharides: a review" Int. J. Biol. Macromol. (2021) 10.1016/j.ijbiomac.2021.07.008

[31]

Zhou "The antidiabetic effect and potential mechanisms of natural polysaccharides based on the regulation of gut microbiota" J. Funct. Foods (2020) 10.1016/j.jff.2020.104222

[32]

Tao "Understanding the gut-kidney axis among biopsy-proven diabetic nephropathy, type 2 diabetes mellitus and healthy controls: an analysis of the gut microbiota composition" Acta Diabetol. (2019) 10.1007/s00592-019-01316-7

[33]

Zhao "Tangshen formula modulates gut microbiota and reduces gut-derived toxins in diabetic nephropathy rats" Biomed. Pharmacother. (2020) 10.1016/j.biopha.2020.110325

[34]

Chi "The immunomodulatory effect of the gut microbiota in kidney disease" J Immunol Res (2021) 10.1155/2021/5516035

[35]

The Probiotic Lactobacillus fermentum Prevents Dysbiosis and Vascular Oxidative Stress in Rats with Hypertension Induced by Chronic Nitric Oxide Blockade

Iñaki Robles‐Vera, Marta Toral, Nestor de la Visitacion et al.

Molecular Nutrition & Food Research 2018 10.1002/mnfr.201800298

[36]

Yuan "Punicic acid ameliorates obesity and liver steatosis by regulating gut microbiota composition in mice" Food Funct. (2021) 10.1039/d1fo01152a

[37]

Henke "Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide" Proc. Natl. Acad. Sci. U. S. A. (2019) 10.1073/pnas.1904099116

[38]

Azzouz "Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal" Ann. Rheum. Dis. (2019) 10.1136/annrheumdis-2018-214856

[39]

Yang "Polysaccharides from armillariella tabescens mycelia ameliorate renal damage in type 2 diabetic mice" Int. J. Biol. Macromol. (2020) 10.1016/j.ijbiomac.2020.08.006

[40]

Role of gut microbiota in type 2 diabetes pathophysiology

Manoj Gurung, Zhipeng Li, Hannah You et al.

EBioMedicine 2020 10.1016/j.ebiom.2019.11.051

[41]

Ropot "Cultivation of the next-generation probiotic akkermansia muciniphila, methods of its safe delivery to the intestine, and factors contributing to its growth in vivo" Curr. Microbiol. (2020) 10.1007/s00284-020-01992-7

[42]

Depommier "Supplementation with akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study" Nat. Med. (2019) 10.1038/s41591-019-0495-2

[43]

Zhang "Akkermansia muciniphila can reduce the damage of gluco/lipotoxicity, oxidative stress and inflammation, and normalize intestine microbiota in streptozotocin-induced diabetic rats" Pathog. Dis. (2018) 10.1093/femspd/fty028

[44]

Ethanol extract of Sargarsum fusiforme alleviates HFD/STZ-induced hyperglycemia in association with modulation of gut microbiota and intestinal metabolites in type 2 diabetic mice

Siya Wu, Jihui Zuo, Yang Cheng et al.

Food Research International 2021 10.1016/j.foodres.2021.110550

[45]

Cobo "First description of abdominal infection due to alistipes onderdonkii" Anaerobe (2020) 10.1016/j.anaerobe.2020.102283

[46]

Dowarah "The use of lactobacillus as an alternative of antibiotic growth promoters in pigs: a review" Anim. Nutr. (2017) 10.1016/j.aninu.2016.11.002

[47]

Investigation of gut microbiome changes in type 1 diabetic mellitus rats based on high-throughput sequencing

Quantao Ma, Yaqi Li, Jingkang Wang et al.

Biomedicine & Pharmacotherapy 2020 10.1016/j.biopha.2020.109873

[48]

Li "The positive effects and underlying mechanisms of undaria pinnatifida polysaccharides on type 2 diabetes mellitus in rats" Food Funct. (2021) 10.1039/d1fo01838h

[49]

Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals

Kate L. Ormerod, David L. A. Wood, Nancy Lachner et al.

Microbiome 2016 10.1186/s40168-016-0181-2

[50]

Smith "Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice" BMC Microbiol. (2019) 10.1186/s12866-019-1494-7

Showing 50 of 63 references

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References

Details

Published: May 01, 2022
Vol/Issue: 206
Pages: 849-860
License: View

Authors

Liaoning University

Department of Cell and Developmental Biology and the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, 121 Taylor Hall CB No. 7090, Chapel Hill, North Carolina 27599, and Department of Biochemistry, University of Illinois, Urbana, Illinois 61801

Northwestern University

Cite This Article

Meng Zhang, Licheng Yang, Maomao Zhu, et al. (2022). Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats. International Journal of Biological Macromolecules, 206, 849-860. https://doi.org/10.1016/j.ijbiomac.2022.03.077

Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats

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