Topics

No keywords indexed for this article. Browse by subject →

References
39
[1]
de Brito e Cunha "Biotechnological evolution of siRNA molecules: from bench tool to the refined drug" Pharmaceuticals (2022) 10.3390/ph15050575
[2]
Setten "The current state and future directions of RNAi-based therapeutics" Nat. Rev. Drug Discov. (2019) 10.1038/s41573-019-0017-4
[3]
Sajid "Overcoming barriers for siRNA therapeutics: from bench to bedside" Pharmaceuticals (2020) 10.3390/ph13100294
[4]
Engineering siRNA therapeutics: challenges and strategies

Syed Saqib Ali Zaidi, Faria Fatima, Syed Aqib Ali Zaidi et al.

Journal of Nanobiotechnology 2023 10.1186/s12951-023-02147-z
[5]
Zhao "Targeting strategies for tissue-specific drug delivery" Cell (2020) 10.1016/j.cell.2020.02.001
[6]
Kedmi "A modular platform for targeted RNAi therapeutics" Nat. Nanotechnol. (2018) 10.1038/s41565-017-0043-5
[7]
Roth "Identification of receptor-interacting regions of Vitellogenin within evolutionarily conserved β-sheet structures by using a peptide array" ChemBioChem (2013) 10.1002/cbic.201300152
[8]
Roth "Identification and characterization of the vitellogenin receptor in Macrobrachium rosenbergii and its expression during vitellogenesis" Mol. Reprod. Dev. (2012) 10.1002/mrd.22055
[9]
Cohen "A crustacean vitellogenin-derived peptide as an oocyte-specific delivery vehicle for gene silencing" Front. Mar. Sci. (2023) 10.3389/fmars.2023.1128524
[10]
Ilouz "A protein chimera for dsRNA binding and delivery into oocytes for large-scale gene silencing in crustacean aquaculture" Aquaculture (2024) 10.1016/j.aquaculture.2023.740321
[11]
Anderson "The structural basis of lipid interactions in lipovitellin, a soluble lipoprotein" Structure (1998) 10.1016/s0969-2126(98)00091-4
[12]
Li "Receptor-ligand interaction between Vitellogenin receptor (VtgR) and Vitellogenin (Vtg), implications on low density lipoprotein receptor and apolipoprotein B/E" J. Biol. Chem. (2003) 10.1074/jbc.m205067200
[13]
Babin "Apolipophorin II/I, apolipoprotein B, vitellogenin, and microsomal triglyceride transfer protein genes are derived from a common ancestor" J. Mol. Evol. (1999) 10.1007/pl00006528
[14]
Maillard "Inactivation of the type I interferon pathway reveals long double-stranded RNA-mediated RNA interference in mammalian cells" EMBO J. (2016) 10.15252/embj.201695086
[15]
Kulmann "Enhanced RNAi does not provide efficient innate antiviral immunity in mice" Nucleic Acids Res. (2025) 10.1093/nar/gkae1288
[16]
Saitou "The neighbor-joining method: a new method for reconstructing phylogenetic trees" Mol. Biol. Evol. (1987)
[17]
MEGA11: Molecular Evolutionary Genetics Analysis Version 11

Koichiro Tamura, Glen Stecher, Sudhir Kumar

Molecular Biology and Evolution 2021 10.1093/molbev/msab120
[18]
MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

Sudhir Kumar, Glen Stecher, Michael Li et al.

Molecular Biology and Evolution 2018 10.1093/molbev/msy096
[19]
Felsenstein "Confidence limits on phylogenies: an approach using the bootstrap" Evolution (N Y). (1985)
[20]
Evolutionary Divergence and Convergence in Proteins

Emile Zuckerkandl, Linus Pauling

Evolving Genes and Proteins 1965 10.1016/b978-1-4832-2734-4.50017-6
[21]
Lewis "Matrix-assisted laser desorption/ionization mass spectrometry in peptide and protein analysis" (2000)
[22]
Highly accurate protein structure prediction with AlphaFold

John Jumper, Richard Evans, Alexander Pritzel et al.

Nature 2021 10.1038/s41586-021-03819-2
[23]
Target Gene Abundance Contributes to the Efficiency of siRNA-Mediated Gene Silencing

Sun Woo Hong, Yuanyuan Jiang, Soyoun Kim et al.

Nucleic Acid Therapeutics 2014 10.1089/nat.2013.0466
[24]
Nigon "Discrete subspecies of human low density lipoproteins are heterogeneous in their interaction with the cellular LDL receptor" J. Lipid Res. (1991) 10.1016/s0022-2275(20)41629-3
[25]
Calabuig-Navarro "A randomized trial and novel SPR technique identifies altered lipoprotein-LDL receptor binding as a mechanism underlying elevated LDL-cholesterol in APOE4s" Sci. Rep. (2017) 10.1038/srep44119
[26]
Johnston "A conserved double-stranded RNA-binding domain" Proc. Natl. Acad. Sci. (1992) 10.1073/pnas.89.22.10979
[27]
Masliah "RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence" Cell. Mol. Life Sci. (2012)
[28]
Bou-Nader "Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2" Nucleic Acids Res. (2019) 10.1093/nar/gky1302
[29]
Liu "Staufen dsRNA-binding domain as modules to design bifunctional antibodies for siRNA delivery" Nucleic Acids Res. (2026) 10.1093/nar/gkaf1539
[30]
Bevilacqua "Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR" Biochemistry (1996) 10.1021/bi9607259
[31]
Li "Highly efficient delivery of siRNA to a heart transplant model by a novel cell penetrating peptide-dsRNA binding domain" Int. J. Pharm. (2014) 10.1016/j.ijpharm.2014.04.050
[32]
Wostenberg "The role of human dicer-dsRBD in processing small regulatory RNAs" PLoS One (2012) 10.1371/journal.pone.0051829
[33]
Foroozandeh "Merging worlds of nanomaterials and biological environment: factors governing protein Corona formation on nanoparticles and its biological consequences" Nanoscale Res. Lett. (2015) 10.1186/s11671-015-0922-3
[34]
Sorkin "Clathrin-mediated endocytosis" (2014)
[35]
Mechanisms of clathrin-mediated endocytosis

Marko Kaksonen, Aurelien Roux

Nature Reviews Molecular Cell Biology 2018 10.1038/nrm.2017.132
[36]
Strategies and mechanisms for endosomal escape of therapeutic nucleic acids

Melina Grau, Ernst Wagner

Current Opinion in Chemical Biology 2024 10.1016/j.cbpa.2024.102506
[37]
Lönn "Enhancing endosomal escape for intracellular delivery of macromolecular biologic therapeutics" Sci. Rep. (2016) 10.1038/srep32301
[38]
Heath "Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo" Nanomedicine (2019) 10.2217/nnm-2019-0061
[39]
Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

Yajun Duan, Ke Gong, Suowen Xu et al.

Signal Transduction and Targeted Therapy 2022 10.1038/s41392-022-01125-5
Metrics
0
Citations
39
References
Details
Published
May 01, 2026
Vol/Issue
360
Pages
151876
License
View
Funding
Israel Science Foundation Award: 302/21
Israel Innovation Authority Award: 70021
Cite This Article
Yuval Malca, Mahdi Hasan, Shany Cohen, et al. (2026). Facilitating siRNA delivery into mammalian cells via the LDL receptor. International Journal of Biological Macromolecules, 360, 151876. https://doi.org/10.1016/j.ijbiomac.2026.151876
Related

You May Also Like