Non-specialist interpersonal psychotherapy versus fluoxetine for major depression and post-traumatic stress disorder in Kenyan public-sector primary care: a sequential, multiple-assignment, randomised trial

Susan M Meffert; Muthoni A Mathai; Linnet Ongeri; Thomas C Neylan; Daniel Mwai; Dickens Onyango; Dickens Akena; Grace Rota; Ammon Otieno; Anne Mbwayo; James G Kahn; Craig R Cohen; David Bukusi; Gregory A Aarons; Rachel L Burger; Chengshi Jin; Charles E McCulloch; Simon Njuguna Kahonge

doi:10.1016/j.lanprc.2026.100117

journal article Open Access Mar 01, 2026

Non-specialist interpersonal psychotherapy versus fluoxetine for major depression and post-traumatic stress disorder in Kenyan public-sector primary care: a sequential, multiple-assignment, randomised trial

Susan M Meffert

Muthoni A Mathai Linnet Ongeri Thomas C Neylan Daniel Mwai Dickens Onyango Dickens Akena Grace Rota

Ammon Otieno Anne Mbwayo James G Kahn Craig R Cohen David Bukusi Gregory A Aarons Rachel L Burger Chengshi Jin Charles E McCulloch

Simon Njuguna Kahonge

The Lancet Primary Care Vol. 2 No. 3 pp. 100117 · Elsevier BV

View at Publisher Save 10.1016/j.lanprc.2026.100117

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Details

Published: Mar 01, 2026
Vol/Issue: 2(3)
Pages: 100117
License: View

Authors

Kisumu County Department of Health, Kisumu, Kenya

Institute for Health Policy Studies, University of California – San Francisco, San Francisco, USA.

C

Craig R Cohen

Departments of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco

Simon Njuguna Kahonge

Funding

National Institute of Mental Health

Global Alliance for Chronic Diseases

Cite This Article

Susan M Meffert, Muthoni A Mathai, Linnet Ongeri, et al. (2026). Non-specialist interpersonal psychotherapy versus fluoxetine for major depression and post-traumatic stress disorder in Kenyan public-sector primary care: a sequential, multiple-assignment, randomised trial. The Lancet Primary Care, 2(3), 100117. https://doi.org/10.1016/j.lanprc.2026.100117

Non-specialist interpersonal psychotherapy versus fluoxetine for major depression and post-traumatic stress disorder in Kenyan public-sector primary care: a sequential, multiple-assignment, randomised trial

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