Dose calculation algorithm evaluation for cardiac radioablation of ventricular tachycardia

Michael T. Prusator; Thomas R. Mazur; Wesley W. Tucker; Francisco J. Reynoso; Matthew B. Schmidt; Pamela P. Samson; Cliff G. Robinson; Phillip Cuculich; Sreekrishna Murty Goddu; Kaitlin Moore; Geoffrey D. Hugo; Daniel Cooper; Rugheed Ghadban; Nels C. Knutson

doi:10.1016/j.meddos.2026.02.002

journal article Open Access Apr 01, 2026

Dose calculation algorithm evaluation for cardiac radioablation of ventricular tachycardia

Michael T. Prusator

Thomas R. Mazur Wesley W. Tucker

Francisco J. Reynoso

Matthew B. Schmidt Pamela P. Samson Cliff G. Robinson Phillip Cuculich Sreekrishna Murty Goddu Kaitlin Moore

Geoffrey D. Hugo

Daniel Cooper Rugheed Ghadban Nels C. Knutson

Medical Dosimetry · Elsevier BV

View at Publisher Save 10.1016/j.meddos.2026.02.002

Topics

No keywords indexed for this article. Browse by subject →

References

40

[1]

2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death

Sana M. Al-Khatib, William G. Stevenson, Michael J. Ackerman et al.

Journal of the American College of Cardiology 2018 10.1016/j.jacc.2017.10.054

[2]

Tang "Team management of the ventricular tachycardia patient" Arrhythm Electrophysiol Rev (2018) 10.15420/aer.2018.37.2

[3]

Meta-Analysis of Catheter Ablation Outcomes in Patients With Cardiac Sarcoidosis Refractory Ventricular Tachycardia

Mehul Adhaduk, Bishow Paudel, Kan Liu et al.

The American Journal of Cardiology 2022 10.1016/j.amjcard.2022.03.038

[4]

Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia

Cliff G. Robinson, Pamela P. Samson, Kaitlin M.S. Moore et al.

Circulation 2019 10.1161/circulationaha.118.038261

[5]

Cuculich "Noninvasiv cardiac radiation for ablation of ventricular tachycardia" N Engl J Med (2017) 10.1056/nejmoa1613773

[6]

Chang "Stereotactic body radiation therapy: a comprehensive review" Am J Clin Oncol (2007) 10.1097/coc.0b013e3180ca7cb1

[7]

Knutson "Radiation therapy workflow and dosimetric analysis from a phase ½ trial of noninvasive cardiac radioablation for ventricular tachycardia" Int J Radiat Oncol Biol Phys (2019) 10.1016/j.ijrobp.2019.04.005

[8]

Wang "Stereotactic arrhythmia radioablation (STAR) of ventricular tachycardia: a treatment planning study" Cureus (2016)

[9]

Stereotactic arrhythmia radioablation for refractory scar-related ventricular tachycardia

Carola Gianni, Douglas Rivera, J. David Burkhardt et al.

Heart Rhythm 2020 10.1016/j.hrthm.2020.02.036

[10]

Tillikainen "A 3D pencil-beam-based superposition algorithm for photon dose calculation in heterogeneous media" Phys Med Biol (2008) 10.1088/0031-9155/53/14/008

[11]

Fogliata "Dosimetric validation of the Acuros XB advanced dose calculation algorithm: fundamental characterization In water" Phys Med Biol (2011) 10.1088/0031-9155/56/6/022

[12]

Ma "Beam modeling and Beam model commissioning for Monte Carlo dose calculation-based radiation therapy treatment planning: report of AAPM Task Group 157" Med Phys (2020) 10.1016/j.ejmp.2020.06.021

[13]

Chetty "Report of The AAPM Task Group No. 105: issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planning" Med Phys (2007) 10.1118/1.2795842

[14]

Jabbari "Review of fast Monte Carlo codes for dose calculation In radiation therapy treatment planning" J Med Signals Sens (2011) 10.4103/2228-7477.83522

[15]

Cerqueira "Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart" Circulation (2002) 10.1161/hc0402.102975

[16]

Timmerman "An overview of hypofractionation and introduction to this issue of seminars in radiation oncology" Semin Radiat Oncol (2008) 10.1016/j.semradonc.2008.04.001

[17]

(2025)

[18]

Benedict "Stereotactic body radiation therapy: the report of AAPM Task Group 101" Med Phys (2012) 10.1118/1.3671956

[19]

Blanck "Radiosurgery for ventricular tachycardia: preclinical and clinical evidence and study design for a German multi-center multi-platform feasibility trial (RAVENTA)" Clin Res Cardiol (2020) 10.1007/s00392-020-01650-9

[20]

Sempau "DPM, a fast, accurate Monte Carlo code optimized for photon and electron radiotherapy treatment planning dose calculations" Phys Med Biol (2000) 10.1088/0031-9155/45/8/315

[21]

Chetty I, Tyagi N, Rosu M et al. April 6-10, 2003. Clinical Implementation, validation and use of the DPM Monte Carlo code for radiotherapy treatment planning. Nuclear mathematical and computational sciences: a century in review, a century anew, Gatlinburg, TN. doi:10.31382/NSE05-A7368.

[22]

Li "Monte Carlo simulation of linac using PRIMO" Radiat Oncol (2022) 10.1186/s13014-022-02149-5

[23]

Calvo-Ortega "PRIMO Monte Carlo software as a tool for commissioning of an external beam radiotherapy treatment planning system" Rep Pract Oncol Radiother (2023) 10.5603/rpor.a2023.0060

[24]

Rodriguez "PRIMO: a graphical environment for the Monte Carlo simulation of Varian and Elekta linacs" Strahlenther Onkol (2013) 10.1007/s00066-013-0415-1

[25]

A technique for the quantitative evaluation of dose distributions

Daniel A. Low, William B. Harms, Sasa Mutic et al.

Medical Physics 1998 10.1118/1.598248

[26]

Pulliam "Comparison of 2D and 3D gamma analyses" Med Phys (2014) 10.1118/1.4860195

[27]

Low "Evaluation of the gamma dose distribution comparison method" Med Phys (2003) 10.1118/1.1598711

[28]

Depuydt "A quantitative evaluation of IMRT dose distributions: refinement and clinical assessment of the gamma evaluation" Radiother Oncol (2002) 10.1016/s0167-8140(01)00497-2

[29]

Wall "Prospective clinical validation of virtual patient-specific quality assurance of volumetric modulated arc therapy radiation therapy plans" Int J Radiat Oncol Biol Phys (2022) 10.1016/j.ijrobp.2022.04.040

[30]

Hussein "Challenges in calculation of the gamma index in radiotherapy–towards good practice" Phys Med (2017) 10.1016/j.ejmp.2017.03.001

[31]

Knutson "Equivalency of beam scan data collection using a 1D tank and automated couch movements to traditional 3D tank measurements" J Appl Clin Med Phys (2018) 10.1002/acm2.12444

[32]

Fogliata "Dose calculation algorithm accuracy for small fields in non-homogeneous media: the lung SBRT case" Phys Med (2017) 10.1016/j.ejmp.2016.11.104

[33]

Singh "Dosimetric assessment of conventional and advanced algorithms in clinical stereotactic radiotherapy" Precis Radiat Oncol (2025) 10.1002/pro6.70028

[34]

Padmanaban "Comparison of Acuros (AXB) and anisotropic analytical algorithm (AAA) for dose calculation in treatment of oesophageal cancer: effects on modelling tumour control probability" Radiat Oncol (2024)

[35]

Srivastava "A comparative analysis of Acuros XB and the analytical anisotropic algorithm for volumetric modulation arc therapy" Rep Pract Oncol Radiother (2021) 10.5603/rpor.a2021.0050

[36]

Fogliata "On the dosimetric impact of inhomogeneity management in the Acuros XB algorithm for breast treatment" Radiat Oncol (2011)

[37]

Han "Dosimetric impact of Acuros XB deterministic radiation transport algorithm for heterogeneous dose calculation in lung cancer" Med Phys (2013) 10.1118/1.4802216

[38]

Kroon "Dosimetric accuracy and clinical quality of Acuros XB and AAA dose calculation algorithm for stereotactic and conventional lung volumetric modulated Arc therapy plans" Radiat Oncol (2013)

[39]

Roh "Verification of rebuild-up effect on superficial cardiac lesion of ventricular tachycardia using 3-D printed phantom in volumetric-modulated Arc therapy planning" Sci Rep (2022) 10.1038/s41598-022-05149-3

[40]

Viani "A meta-analysis of the efficacy and safety of stereotactic arrhythmia radioablation (STAR) in patients with refractory ventricular tachycardia" Clin Oncol (2023) 10.1016/j.clon.2023.04.004

Metrics

0

Citations

40

References

Details

Published: Apr 01, 2026
License: View

Authors

Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA

Department of Radiation Oncology Washington University St. Louis Missouri

C

Cliff G. Robinson

Department of Radiation Oncology Washington University St. Louis Missouri

P

Phillip Cuculich

S

Sreekrishna Murty Goddu

Department of Radiation Oncology (C.G.R., P.P.S., G.D.H., N.K., S.M., S.M.G., D.E.H.), Washington University, St Louis, MO.

D

Daniel Cooper

DataGrade Solutions, LLC, Miami, Florida 33173, United States

Cite This Article

Michael T. Prusator, Thomas R. Mazur, Wesley W. Tucker, et al. (2026). Dose calculation algorithm evaluation for cardiac radioablation of ventricular tachycardia. Medical Dosimetry. https://doi.org/10.1016/j.meddos.2026.02.002

Dose calculation algorithm evaluation for cardiac radioablation of ventricular tachycardia

You May Also Like