Cathepsin C aggravates neuroinflammation via promoting production of CCL2 and CXCL2 in glial cells and neurons in a cryogenic brain lesion

Adkison "Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis" J. Clin. Invest. (2002) 10.1172/jci0213462

[2]

Akk "Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection" J. Immunol. (2008) 10.4049/jimmunol.180.5.3535

[3]

Astrup "Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology" Neurol. Res. (2019) 10.1080/01616412.2019.1573455

[4]

Cytokine networks in neuroinflammation

Burkhard Becher, Sabine Spath, Joan Goverman

Nature Reviews Immunology 2017 10.1038/nri.2016.123

[5]

Bernstein "Immunodetection of cathepsin D in neuritic plaques found in brains of patients with dementia of Alzheimer type" J. Hirnforsch. (1989)

[6]

Bourbeau "New and controversial therapies for chronic obstructive pulmonary disease" Proc. Am. Thorac. Soc. (2009) 10.1513/pats.200906-039ds

[7]

Boutte "Penetrating traumatic brain injury triggers dysregulation of Cathepsin B protein levels independent of cysteine protease activity in brain and cerebral spinal fluid" J. Neurotrauma (2020) 10.1089/neu.2019.6537

[8]

Cagnin "In-vivo measurement of activated microglia in dementia" Lancet (2001) 10.1016/s0140-6736(01)05625-2

[9]

Cederberg "What has inflammation to do with traumatic brain injury?" Childs Nerv. Syst. (2010) 10.1007/s00381-009-1029-x

[10]

Charo "The many roles of chemokines and chemokine receptors in inflammation N" Engl. J. Med. (2006) 10.1056/nejmra052723

[11]

Czapski "Systemic administration of lipopolysaccharide induces molecular and morphological alterations in the hippocampus" Brain Res. (2010) 10.1016/j.brainres.2010.07.096

[12]

Dambach "Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation" Epilepsia (2014) 10.1111/epi.12473

[13]

Day "Regulation of neutrophil trafficking from the bone marrow" Cell. Mol. Life Sci. (2012) 10.1007/s00018-011-0870-8

[14]

De Filippo "Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation" Blood (2013) 10.1182/blood-2013-02-486217

[15]

Deussing "Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13" Genomics (2002) 10.1006/geno.2002.6696

[16]

Dimitrijevic "Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice" Stroke (2007) 10.1161/01.str.0000259709.16654.8f

[17]

Durose "Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis" J. Neurochem. (2018) 10.1111/jnc.14581

[18]

Dzenko "The chemokine receptor CCR2 mediates the binding and internalization of monocyte chemoattractant protein-1 along brain microvessels" J. Neurosci. (2001) 10.1523/jneurosci.21-23-09214.2001

[19]

Fan "Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation" J. Neuroinflammation (2012) 10.1186/1742-2094-9-96

[20]

Gaetz "The neurophysiology of brain injury" Clin. Neurophysiol. (2004) 10.1016/s1388-2457(03)00258-x

[21]

Giovannoni "The role of astrocytes in CNS inflammation" Trends Immunol. (2020) 10.1016/j.it.2020.07.007

[22]

Groblewska "The role of selected chemokines and their receptors in the development of gliomas" Int. J. Mol. Sci. (2020) 10.3390/ijms21103704

[23]

Guo "Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage" Faseb. J. (2020) 10.1096/fj.201902203rr

[24]

Gyoneva "Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell-cell communication by chemokines" Trends Pharmacol. Sci. (2015) 10.1016/j.tips.2015.04.003

[25]

Hamon "Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases" J. Biol. Chem. (2016) 10.1074/jbc.m115.707109

[26]

Hu "Dipeptidyl peptidase I regulates the development of collagen-induced arthritis" Arthritis Rheum. (2005) 10.1002/art.21192

[27]

Ishidoh "Molecular cloning of cDNA for rat cathepsin C. Cathepsin C, a cysteine proteinase with an extremely long propeptide" J. Biol. Chem. (1991) 10.1016/s0021-9258(18)55298-4

[28]

Jassam "Neuroimmunology of traumatic brain injury: time for a paradigm shift" Neuron (2017) 10.1016/j.neuron.2017.07.010

[29]

Karababa "Ammonia attenuates LPS-induced upregulation of pro-inflammatory cytokine mRNA in Co-cultured astrocytes and microglia" Neurochem. Res. (2017) 10.1007/s11064-016-2060-4

[30]

Karim "Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination" Proc. Natl. Acad. Sci. U.S.A. (2018) 10.1073/pnas.1721732115

[31]

Kingham "Microglial apoptosis induced by chromogranin A is mediated by mitochondrial depolarisation and the permeability transition but not by cytochrome c release" J. Neurochem. (2000) 10.1046/j.1471-4159.2000.0741452.x

[32]

Liang "Disinhibition of cathepsin C caused by cystatin F deficiency aggravates the demyelination in a cuprizone model" Front. Mol. Neurosci. (2016) 10.3389/fnmol.2016.00152

[33]

Linnerbauer "Astrocyte crosstalk in CNS inflammation" Neuron (2020) 10.1016/j.neuron.2020.08.012

[34]

Liu "Interaction of microglia and astrocytes in the neurovascular unit" Front. Immunol. (2020) 10.3389/fimmu.2020.01024

[35]

Liu "Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway" J. Neuroinflammation (2019) 10.1186/s12974-019-1398-3

[36]

Ma "Microglial cystatin F expression is a sensitive indicator for ongoing demyelination with concurrent remyelination" J. Neurosci. Res. (2011) 10.1002/jnr.22567

[37]

Maas "Moderate and severe traumatic brain injury in adults" Lancet Neurol. (2008) 10.1016/s1474-4422(08)70164-9

[38]

Mahad "Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis" Brain (2005)

[39]

Mallen-St "Mast cell dipeptidyl peptidase I mediates survival from sepsis" J. Clin. Invest. (2004) 10.1172/jci200419062

[40]

Traumatic Brain Injury: A Disease Process, Not an Event

Brent E. Masel, Douglas S. DeWitt

Journal of Neurotrauma 2010 10.1089/neu.2010.1358

[41]

McGuire "Purification and characterization of dipeptidyl peptidase I from human spleen" Arch. Biochem. Biophys. (1992) 10.1016/0003-9861(92)90519-3

[42]

McGuire "Cloning and characterization of the cDNA encoding mouse dipeptidyl peptidase I (cathepsin C)" Biochim. Biophys. Acta (1997) 10.1016/s0167-4781(97)00021-3

[43]

Molnar "Associations between serum L-arginine and ficolins in the early phase of acute ischemic stroke - a pilot study" J. Stroke Cerebrovasc. Dis. (2020) 10.1016/j.jstrokecerebrovasdis.2020.104951

[44]

Nakanishi "Age-related changes in activities and localizations of cathepsins D, E, B, and L in the rat brain tissues" Exp. Neurol. (1994) 10.1006/exnr.1994.1048

[45]

Pagano "Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms" Proc. Natl. Acad. Sci. U.S.A. (2007) 10.1073/pnas.0606091104

[46]

Paris "Molecular cloning and sequence analysis of human preprocathepsin C" FEBS Lett. (1995) 10.1016/0014-5793(95)00777-7

[47]

Petanceska "Expression of rat cathepsin S in phagocytic cells" J. Biol. Chem. (1996) 10.1074/jbc.271.8.4403

[48]

Pham "Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo" Proc. Natl. Acad. Sci. U.S.A. (1999) 10.1073/pnas.96.15.8627

[49]

Rajarathnam "How do chemokines navigate neutrophils to the target site: dissecting the structural mechanisms and signaling pathways" Cell. Signal. (2019) 10.1016/j.cellsig.2018.11.004

[50]

Neuroinflammation: Ways in Which the Immune System Affects the Brain

Richard M. Ransohoff, Dorothy Schafer, Angela Vincent et al.

Neurotherapeutics 2015 10.1007/s13311-015-0385-3

Showing 50 of 74 references

Cited By

29

Quercetin protects against sepsis-associated encephalopathy by inhibiting microglia-neuron crosstalk via the CXCL2/CXCR2 signaling pathway

Yu-Shen Yang, Chu-Yun Liu · 2024

Phytomedicine

Cathepsin C inhibitors as anti-inflammatory drug discovery: Challenges and opportunities

Xiao Bao Shen, Xing Chen · 2021

European Journal of Medicinal Chemi...

Metrics

29

Citations

74

References

Details

Published: Sep 01, 2021
Vol/Issue: 148
Pages: 105107
License: View

Authors

X

Xinnan Zhao

Department of Anatomy, College of Basic Medical Sciences, Dalian Medical University , Dalian, Liaoning , China

Department of Building, Civil and Environmental Engineering, Concordia University, Montreal, QC H3G 1M8, Canada

G

Gang Liu

Metabolic Disease Research, Global Pharmaceutical Research and Discovery Organization, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064-6098

Department of Anatomy, College of Basic Medical Sciences, Dalian Medical University , Dalian, Liaoning , China; National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University , Dalian, Liaoning , China

Cite This Article

Xinnan Zhao, Shuang Liu, Xiaohan Yang, et al. (2021). Cathepsin C aggravates neuroinflammation via promoting production of CCL2 and CXCL2 in glial cells and neurons in a cryogenic brain lesion. Neurochemistry International, 148, 105107. https://doi.org/10.1016/j.neuint.2021.105107

Cathepsin C aggravates neuroinflammation via promoting production of CCL2 and CXCL2 in glial cells and neurons in a cryogenic brain lesion

You May Also Like