Fluorogenic Labeling Probe for the Imaging of Endogenous β-Galactosidase Activity in Cancer and Senescent Cells

Jing-Bo Wang; Xue-Ru Zhao; Xi-Le Hu; Yi Zang; Jia Li; Xiao-Peng He

doi:10.1021/acsami.4c15268

journal article Dec 09, 2024

Fluorogenic Labeling Probe for the Imaging of Endogenous β-Galactosidase Activity in Cancer and Senescent Cells

Jing-Bo Wang Xue-Ru Zhao Xi-Le Hu Yi Zang

Jia Li

Xiao-Peng He

ACS Applied Materials & Interfaces Vol. 16 No. 50 pp. 68918-68927 · American Chemical Society (ACS)

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Details

Published: Dec 09, 2024
Vol/Issue: 16(50)
Pages: 68918-68927
License: View

Authors

J

Jing-Bo Wang

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China

X

Xue-Ru Zhao

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

X

Xi-Le Hu

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China

Y

Yi Zang

Lingang Laboratory, Shanghai 201203, China

J

Jia Li

State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

X

Xiao-Peng He

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd., Shanghai 200237, China; National Center for Liver Cancer, the International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China

Funding

National Natural Science Foundation of China Award: 22108077

Fundamental Research Funds for the Central Universities Award: 222201717003

State Key Laboratory of Bioreactor Engineering

State Key Laboratory of Chemo/Biosensing and Chemometrics

International Cooperation Program of Shanghai Science and Technology Award: 23490711600

Ministry of Education Key Laboratory on signaling Regulation and Targeting Therapy of Liver Cancer Award: 2023-MEKLLC-MS/ZD-00*

Cite This Article

Jing-Bo Wang, Xue-Ru Zhao, Xi-Le Hu, et al. (2024). Fluorogenic Labeling Probe for the Imaging of Endogenous β-Galactosidase Activity in Cancer and Senescent Cells. ACS Applied Materials & Interfaces, 16(50), 68918-68927. https://doi.org/10.1021/acsami.4c15268

Fluorogenic Labeling Probe for the Imaging of Endogenous β-Galactosidase Activity in Cancer and Senescent Cells

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