Design, Synthesis, and Structural Characterization of Thioflavones and Thioflavonols as Potential Tyrosinase Inhibitors: In Vitro and In Silico Studies

Ehsan Ullah Mughal; Jamshaid Ashraf; Essam M. Hussein; Yasir Nazir; Abdulaziz S. Alwuthaynani; Nafeesa Naeem; Amina Sadiq; Reem I. Alsantali; Saleh A. Ahmed

doi:10.1021/acsomega.2c01841

journal article Open Access May 10, 2022

Design, Synthesis, and Structural Characterization of Thioflavones and Thioflavonols as Potential Tyrosinase Inhibitors: In Vitro and In Silico Studies

Ehsan Ullah Mughal

Jamshaid Ashraf Essam M. Hussein Yasir Nazir

Abdulaziz S. Alwuthaynani Nafeesa Naeem

Amina Sadiq

Reem I. Alsantali Saleh A. Ahmed

ACS Omega Vol. 7 No. 20 pp. 17444-17461 · American Chemical Society (ACS)

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Details

Published: May 10, 2022
Vol/Issue: 7(20)
Pages: 17444-17461
License: View

Authors

E

Ehsan Ullah Mughal

Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan

J

Jamshaid Ashraf

Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan

E

Essam M. Hussein

Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia; Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt

Y

Yasir Nazir

Department of Chemistry, Allama Iqbal Open University, Islamabad 44000 Pakistan; Department of Chemistry, University of Sialkot, Sialkot 51300, Pakistan

A

Abdulaziz S. Alwuthaynani

Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia

N

Nafeesa Naeem

Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan

A

Amina Sadiq

Department of Chemistry, Govt. College Women University, Sialkot 51300, Pakistan

R

Reem I. Alsantali

Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

S

Saleh A. Ahmed

Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia; Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt

Funding

Taif University Award: TURSP-2020/312

Higher Education Commission, Pakistan Award: NRPU-15800

Umm Al-Qura University Award: 22UQU4320545DSR12

Cite This Article

Ehsan Ullah Mughal, Jamshaid Ashraf, Essam M. Hussein, et al. (2022). Design, Synthesis, and Structural Characterization of Thioflavones and Thioflavonols as Potential Tyrosinase Inhibitors: In Vitro and In Silico Studies. ACS Omega, 7(20), 17444-17461. https://doi.org/10.1021/acsomega.2c01841

Design, Synthesis, and Structural Characterization of Thioflavones and Thioflavonols as Potential Tyrosinase Inhibitors: In Vitro and In Silico Studies

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