NMR and Crystallographic Characterization of Adventitious Borate Binding by Trypsin

Thomas R. Transue; Scott A. Gabel; Robert E. London

doi:10.1021/bc0502210

journal article Feb 23, 2006

NMR and Crystallographic Characterization of Adventitious Borate Binding by Trypsin

Thomas R. Transue Scott A. Gabel Robert E. London

Bioconjugate Chemistry Vol. 17 No. 2 pp. 300-308 · American Chemical Society (ACS)

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References

41

[1]

Drews J. (1998)

[2]

Druggability Indices for Protein Targets Derived from NMR-Based Screening Data

Philip J. Hajduk, Jeffrey R. Huth, Stephen W. Fesik

Journal of Medicinal Chemistry 2005 10.1021/jm049131r

[3]

Pizer R. (1984)

[4]

Coddington J. M. J. Coord. Chem. (1989) 10.1080/00958978909408845

[5]

Vandenberg R. Carbohydr. Res. (1994)

[6]

van Haveren J. (1989)

[7]

London R. E. J. Am. Chem. Soc. (1994)

[8]

Taler G. Inorg. Chim. Acta (1998) 10.1016/s0020-1693(97)06059-3

[9]

Taler G. J. Magn. Reson. (1999) 10.1006/jmre.1999.1853

[10]

Reuter W. (1999)

[11]

Vos S. J. Mol. Biol. (1998)

[12]

Tulinsky A. J. Biol. Chem. (1987) 10.1016/s0021-9258(18)47630-2

[13]

Adebodun F. J. Am. Chem. Soc. (1988) 10.1021/ja00209a060

[14]

Baldwin J. E. Bioorg. Med. Chem. Lett. (1991)

[15]

Tsilikounas, E., Kettner, C. A., and Bachovchin, W. W. (1993) Boron-11 NMR spectroscopy of peptide boronic acid inhibitor complexes of α-lytic protease − direct evidence for tetrahedral boron in both boron−histidine and boron−serine adduct complexes.Biochemistry 32, 12651−12655. 10.1021/bi00210a013

[16]

Tsilikounas E. (1992)

[17]

Bone R. (1991)

[18]

Bone R. (1989)

[19]

Stoll, V. S., Eger, B. T., Hynes, R. C., Martichonok, V., Jones, J. B., and Pai, E. F. (1998) Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.Biochemistry 37, 451−462. 10.1021/bi971166o

[20]

Holyoak T. (2003)

[21]

Wang X. (2003)

[22]

Chen Y. J. Am. Chem. Soc. (2005)

[23]

Nicola G. (2005)

[24]

London R. E. (2002)

[25]

Transue T. R. (2004)

[26]

Otwinowski Z. (1997)

[27]

Brunger A. T. Acta Crystallogr. (1998)

[28]

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

Wendy D. Cornell, Piotr Cieplak, Christopher I. Bayly et al.

Journal of the American Chemical Society 1995 10.1021/ja00124a002

[29]

Werbelow L. G. J. Phys. Chem. (1981) 10.1021/j150625a035

[30]

Babine R. E. Lett. Drug Des. Discovery (2004) 10.2174/1570180043485617

[31]

Sheidig, A. J., Hynes, T. R., Pelletier, L. A., Wells, J. A., and Kossiakoff, A. A. (1997) Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid β-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): Engineering of inhibitors with altered specifities.Protein Sci. 6, 1806−1824. 10.1002/pro.5560060902

[32]

Werbelow L. G. J. Chem. Phys. (1979) 10.1063/1.437471

[33]

Werbelow L. G. J. Magn. Reson. (1981)

[34]

Werbelow, L. G. (1995) inEncyclopedia of Nuclear Magnetic Resonance(Grant, D. M., Ed.) Vol. 6, pp 4092−4102, John Wiley & Sons, New York.

[35]

Aramini J. (1998)

[36]

Babcock L. (1980)

[37]

London R. E. J. Am. Chem. Soc. (1994)

[38]

Viscosity (1995)

[39]

Antonov V. K. (1968)

[40]

Chapelle, S., and Verchere, J.F. (1988) A11B and13C NMR determination of the structures of borate complexes of pentoses and related sugars.Tetrahedron 44, 4469−4482. 10.1016/s0040-4020(01)86149-4

[41]

Menard R. (1992)

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Citations

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References

Details

Published: Feb 23, 2006
Vol/Issue: 17(2)
Pages: 300-308

Authors

T

Thomas R. Transue

National Institute of Environmental Health Sciences, Laboratory of Structural Biology, Box 12233, Research Triangle Park, North Carolina 27709

S

Scott A. Gabel

National Institute of Environmental Health Sciences, Laboratory of Structural Biology, Box 12233, Research Triangle Park, North Carolina 27709

R

Robert E. London

National Institute of Environmental Health Sciences, Laboratory of Structural Biology, Box 12233, Research Triangle Park, North Carolina 27709

Cite This Article

Thomas R. Transue, Scott A. Gabel, Robert E. London (2006). NMR and Crystallographic Characterization of Adventitious Borate Binding by Trypsin. Bioconjugate Chemistry, 17(2), 300-308. https://doi.org/10.1021/bc0502210

NMR and Crystallographic Characterization of Adventitious Borate Binding by Trypsin

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