Concise Biosynthesis of Antifungal Papulacandins

Chao Yu; Niandi Zhang; Jinmei Li; Mingxin Zheng; Meihui Zhao; Ling-Yan Wang; Zhiqiang An; Gerald F. Bills; Zhuan Zhang

doi:10.1021/jacs.4c13101

journal article Mar 05, 2025

Concise Biosynthesis of Antifungal Papulacandins

Chao Yu

Niandi Zhang Jinmei Li

Mingxin Zheng Meihui Zhao

Ling-Yan Wang Zhiqiang An

Gerald F. Bills

Zhuan Zhang

Journal of the American Chemical Society Vol. 147 No. 11 pp. 9037-9042 · American Chemical Society (ACS)

View at Publisher Save 10.1021/jacs.4c13101

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Details

Published: Mar 05, 2025
Vol/Issue: 147(11)
Pages: 9037-9042
License: View

Authors

C

Chao Yu

NHC Key Laboratory of Biotechnology for Microbial Drugs, State Key Laboratory of Bioactive Substance & Function of Natural Medicines, Institute of Medicinal Biotechnology; Chinese Academy of Medical Sciences & Peking Union Medical College

N

Niandi Zhang

NHC Key Laboratory of Biotechnology for Microbial Drugs, State Key Laboratory of Bioactive Substance & Function of Natural Medicines, Institute of Medicinal Biotechnology; Chinese Academy of Medical Sciences & Peking Union Medical College

J

Jinmei Li

NHC Key Laboratory of Biotechnology for Microbial Drugs, State Key Laboratory of Bioactive Substance & Function of Natural Medicines, Institute of Medicinal Biotechnology; Chinese Academy of Medical Sciences & Peking Union Medical College

M

Mingxin Zheng

NHC Key Laboratory of Biotechnology for Microbial Drugs, State Key Laboratory of Bioactive Substance & Function of Natural Medicines, Institute of Medicinal Biotechnology; Chinese Academy of Medical Sciences & Peking Union Medical College

M

Meihui Zhao

NHC Key Laboratory of Biotechnology for Microbial Drugs, State Key Laboratory of Bioactive Substance & Function of Natural Medicines, Institute of Medicinal Biotechnology; Chinese Academy of Medical Sciences & Peking Union Medical College

L

Ling-Yan Wang

NHC Key Laboratory of Biotechnology for Microbial Drugs, State Key Laboratory of Bioactive Substance & Function of Natural Medicines, Institute of Medicinal Biotechnology; Chinese Academy of Medical Sciences & Peking Union Medical College

Z

Zhiqiang An

Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine; University of Texas Health Science Center at Houston

G

Gerald F. Bills

Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine; University of Texas Health Science Center at Houston

Z

Zhuan Zhang

NHC Key Laboratory of Biotechnology for Microbial Drugs, State Key Laboratory of Bioactive Substance & Function of Natural Medicines, Institute of Medicinal Biotechnology; Chinese Academy of Medical Sciences & Peking Union Medical College

Funding

National Institutes of Health Award: R01GM121458

Fundamental Research Funds for the Central Universities Award: 2022-RC350-09

Welch Foundation Award: AU-0042-20030616

CAMS Innovation Fund for Medical Sciences Award: 2024-2021I2M1030,2023-I2M-2-006

Cite This Article

Chao Yu, Niandi Zhang, Jinmei Li, et al. (2025). Concise Biosynthesis of Antifungal Papulacandins. Journal of the American Chemical Society, 147(11), 9037-9042. https://doi.org/10.1021/jacs.4c13101

Concise Biosynthesis of Antifungal Papulacandins

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