Iridium-Catalyzed Borylation of Strong Alkyl C(sp
                    3
                    )–H Bonds of Sulfonamides Enabled by Triflyl Activation

Saikat Guria; Arkaprava Biswas; Jaitri Das; Xueyuan Yan; Sayan Dey; Jagriti Chaturvedi; Buddhadeb Chattopadhyay

doi:10.1021/jacs.5c15739

journal article Jan 28, 2026

Iridium-Catalyzed Borylation of Strong Alkyl C(sp 3 )–H Bonds of Sulfonamides Enabled by Triflyl Activation

Saikat Guria Arkaprava Biswas Jaitri Das Xueyuan Yan

Sayan Dey

Jagriti Chaturvedi

Buddhadeb Chattopadhyay

Journal of the American Chemical Society Vol. 148 No. 5 pp. 5022-5033 · American Chemical Society (ACS)

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References

107

[1]

10.1038/366529a0

[2]

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

Thomas W. Lyons, Melanie S. Sanford

Chemical Reviews 10.1021/cr900184e

[3]

10.1021/ar200185g

[4]

10.1021/cr5006414

[5]

Mild metal-catalyzed C–H activation: examples and concepts

T. Gensch, M. N. Hopkinson, F. Glorius et al.

Chemical Society Reviews 10.1039/c6cs00075d

[6]

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

Jian He, Masayuki Wasa, Kelvin S. L. Chan et al.

Chemical Reviews 10.1021/acs.chemrev.6b00622

[7]

10.1039/d0sc05944g

[8]

Late-stage C–H functionalization offers new opportunities in drug discovery

Lucas Guillemard, Nikolaos Kaplaneris, Lutz Ackermann et al.

Nature Reviews Chemistry 10.1038/s41570-021-00300-6

[9]

10.1126/science.abq3048

[10]

10.1038/417507a

[11]

10.1021/jacs.5b08707

[12]

10.1038/s41586-020-2831-6

[13]

Transition-Metal-Catalyzed Silylation and Borylation of C–H Bonds for the Synthesis and Functionalization of Complex Molecules

Isaac F. Yu, Jake W. Wilson, John F. Hartwig

Chemical Reviews 10.1021/acs.chemrev.3c00207

[14]

10.1039/d3qo01931d

[15]

10.1021/ar200206a

[16]

10.1126/science.1067074

[17]

10.1021/cr900206p

[18]

10.1021/ja300308c

[19]

10.1039/c2sc20776a

[20]

10.1039/c3cs60418g

[21]

Cobalt-Catalyzed C–H Borylation

Jennifer V. Obligacion, Scott P. Semproni, Paul J. Chirik

Journal of the American Chemical Society 10.1021/ja500712z

[22]

10.1021/jacs.5b02052

[23]

10.1016/j.tet.2017.11.005

[24]

Ir-catalyzed proximal and distal C–H borylation of arenes

Chabush Haldar, Md Emdadul Hoque, Jagriti Chaturvedi et al.

Chemical Communications 10.1039/d1cc05104k

[25]

10.1039/d1cs01012c

[26]

10.1126/science.abm7599

[27]

10.1002/anie.202209539

[28]

10.1126/sciadv.adg3311

[29]

10.1126/science.287.5460.1995

[30]

10.1021/ja064092p

[31]

10.1021/ja305694r

[32]

10.1002/anie.201310000

[33]

10.1002/anie.201409186

[34]

10.1126/science.aad9730

[35]

10.1126/science.aad9289

[36]

10.1002/anie.201509996

[37]

10.1021/jacs.6b13389

[38]

10.1002/chem.201604943

[39]

10.1126/science.aba6146

[40]

10.1002/anie.202105204

[41]

10.1021/ja305596v

[42]

10.1021/ja307956w

[43]

10.1021/om400900z

[44]

10.1039/c3cc42675k

[45]

10.1021/ja400103p

[46]

10.1021/ja403462b

[47]

10.1021/ja3126239

[48]

10.1002/anie.201306769

[49]

10.1002/adsc.201301147

[50]

10.1002/chem.201404362

Showing 50 of 107 references

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Details

Published: Jan 28, 2026
Vol/Issue: 148(5)
Pages: 5022-5033
License: View

Authors

S

Saikat Guria