Stereoselective Characterization of the 1,4-Dihydropyridine Binding Site at L-Type Calcium Channels in the Resting State and the Opened/Inactivated State

Klaus-Jürgen Schleifer

doi:10.1021/jm981114c

journal article May 21, 1999

Stereoselective Characterization of the 1,4-Dihydropyridine Binding Site at L-Type Calcium Channels in the Resting State and the Opened/Inactivated State

Klaus-Jürgen Schleifer

Journal of Medicinal Chemistry Vol. 42 No. 12 pp. 2204-2211 · American Chemical Society (ACS)

View at Publisher Save 10.1021/jm981114c

Topics

No keywords indexed for this article. Browse by subject →

References

37

[1]

Jones S. W J. Bioenerg. Biomembr. (1998) 10.1023/a:1021977304001

[2]

Birnbaumer L. Neuron (1994) 10.1016/0896-6273(94)90021-3

[3]

Striessnig J. Trends Pharmacol. Sci. (1998) 10.1016/s0165-6147(98)01171-7

[4]

Regulla S. EMBO J. (1991) 10.1002/j.1460-2075.1991.tb07919.x

[5]

Nakayama H. Proc. Natl. Acad. Sci. U.S.A. (1991)

[6]

Striessnig J. Proc. Natl. Acad. Sci. U.S.A. (1991) 10.1073/pnas.88.23.10769

[7]

Kalasz H. FEBS Lett. (1993) 10.1016/0014-5793(93)80321-k

[8]

Peterson B. Z. J. Biol. Chem. (1997)

[9]

He M. J. Biol. Chem. (1997)

[10]

Peterson B. Z. J. Biol. Chem. (1996)

[11]

Hockerman G. H. Proc. Natl. Acad. Sci. U.S.A. (1997) 10.1073/pnas.94.26.14906

[12]

Schuster A. EMBO J. (1996)

[13]

Grabner M. Neuron (1996) 10.1016/s0896-6273(00)80037-9

[14]

Mitterdorfer J. J. Biol. Chem. (1996) 10.1074/jbc.271.48.30330

[15]

Triggle D. J. Trends Pharmacol. Sci. (1989) 10.1016/0165-6147(89)90051-5

[16]

SYBYL

[17]

Zbinden, P. PrGen 1.5.6; Biographics Laboratory: Basel, CH, 1997.

[18]

Vedani A. J. Am. Chem. Soc. (1990) 10.1021/ja00168a021

[19]

Dewar M. J. S. J. Am. Chem. Soc. (1985)

[20]

Zbinden P. Quant. Struct-Act. Relat. (1998) 10.1002/(sici)1521-3838(199804)17:02<122::aid-qsar122>3.0.co;2-l

[21]

Vedani A. J. Am. Chem. Soc. (1995) 10.1021/ja00122a030

[22]

Semianalytical treatment of solvation for molecular mechanics and dynamics

W. Clark Still, Anna Tempczyk, Ronald C. Hawley et al.

Journal of the American Chemical Society 1990 10.1021/ja00172a038

[23]

Searle M. S. J. Am. Chem. Soc. (1992) 10.1021/ja00053a003

[24]

Zheng W. Mol. Pharmacol. (1992)

[25]

Bolger G. T. J. Pharmacol. Exp. Ther. (1983)

[26]

Coburn R. A. J. Med. Chem. (1988) 10.1021/jm00119a009

[27]

Cambridge Structural Database

[28]

Schleifer K.-J Pharm. Pharmacol. Lett. (1995)

[29]

Rovnyak G. C. J. Med. Chem. (1995) 10.1021/jm00001a017

[30]

Adachi I. Chem. Pharm. Bull. (1988)

[31]

Höltje H.-D. J. Comput.-Aided Mol. Des. (1987)

[32]

Goldmann S. Chem. (1991)

[33]

Mitterdorfer J. J. Biol. Chem. (1996) 10.1074/jbc.271.48.30330

[34]

Peterson B. Z. J. Biol. Chem. (1996)

[35]

Sinnegger M. J. J. Biol. Chem. (1997) 10.1074/jbc.272.44.27686

[36]

Dewar M. J. S. J. Am. Chem. Soc. (1977) 10.1021/ja00457a006

[37]

The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity

Declan A. Doyle, João Morais Cabral, Richard A. Pfuetzner et al.

Science 1998 10.1126/science.280.5360.69

Metrics

50

Citations

37

References

Details

Published: May 21, 1999
Vol/Issue: 42(12)
Pages: 2204-2211

Authors

K

Klaus-Jürgen Schleifer

Institute for Pharmaceutical Chemistry, Heinrich-Heine-University Düsseldorf, Universitätsstrasse 1, D-40225 Düsseldorf, Germany

Cite This Article

Klaus-Jürgen Schleifer (1999). Stereoselective Characterization of the 1,4-Dihydropyridine Binding Site at L-Type Calcium Channels in the Resting State and the Opened/Inactivated State. Journal of Medicinal Chemistry, 42(12), 2204-2211. https://doi.org/10.1021/jm981114c

Stereoselective Characterization of the 1,4-Dihydropyridine Binding Site at L-Type Calcium Channels in the Resting State and the Opened/Inactivated State

You May Also Like