journal article Jun 01, 2024

Aloe Barbadensis Miller (Aloe Vera)

View at Publisher Save 10.1024/0300-9831/a000797
Abstract
Abstract: Aloe Barbadensis Miller (Aloe Vera, AV) is a widely recognized for its diverse health-promoting, skin care, and medicinal properties. This narrative review provides a comprehensive overview of AV’s bioactive compounds, pharmacological activities, potential applications, its toxic and adverse effects, as well as the clinical evidence supporting AV’s efficacy in disease prevention. AV contains over 200 bioactive compounds, with the inner clear gel of the leaves containing the majority of these compounds. These include phenolic acids (274.5–307.5 mg/100 g), flavonoids. (3.63–4.70 g/kg), polysaccharides (3.82–6.55 g/kg), saponins, alkaloids, terpenoids, and anthraquinone derivatives. Findings from clinical studies involving both humans and animals highlight the therapeutic potential of AV across diverse health domains. The studies demonstrate AV’s efficacy in reducing blood glucose levels, exhibiting antioxidant and immunomodulatory effects, inducing apoptosis in cancer cells, protecting the liver from damage, and displaying antimicrobial properties. In the fields of dermatology and dentistry, AV has also been observed to promote skin and oral health. However, it is imperative to acknowledge potential risks, adhere to recommended dosages, and seek guidance from healthcare experts before employing AV as a natural therapeutic option. Moreover, considering safety concerns, further well-designed randomized controlled trials are necessary to substantiate the potential benefits of AV and comprehensively assess any associated risks.
Topics

No keywords indexed for this article. Browse by subject →

References
141
[8]
Tariq H Biomed Res Int (2019)
[11]
AMRI. Aloe Medical Group International. Preserving valuable knowledge. Medicinal plants of ancient [Internet]. [cited 2019 May 3]. Available from: https://www.aloe-medical-group.com/en/aloe-vera/history.html
[13]
Nia AF IJAAR (2015)
[14]
Tucker AO, Duke JA, Foster S. Botanical nomenclature of medicinal plants. Vol. 4. In: Cracker LE, Simon JE, editors. Herbs, spices and medicinal plants. Phoenix, AR: Oryx Press; 1989. 169–242.
[16]
Manvitha K J Pharmacog Phytochemistry (2014)
[17]
Asghari R Pertanika J Trop Agric Sci (2018)
[18]
Yavari Z J Chem Health Risks (2013)
[20]
Hazrati S Intl Res J Appl Basic Sci (2012)
[21]
Gupta S Int J Pharm Bio Sci (2014)
[22]
Ahmed M IJCBS (2013)
[24]
Haque MZ J Appl Chem (2014)
[25]
Adesuyi AO Current Res J Biol Sci (2012)
[26]
Cervantes JL J Appl Res Med Aromatic Plants (2018)
[28]
Bhattacharya M J Pharm Res (2011)
[29]
Irma NYAE Res J Recent Sci (2016)
[32]
Sathyaprabha G J Pharm Res (2010)
[35]
Saljooghianpour M Afr J Biotechnol (2013)
[43]
Gao Y Crit Rev Food Sci Nutr (2018)
[44]
Choi SM Int J Biosci Biotech (2016)

Showing 50 of 141 references

Metrics
25
Citations
141
References
Details
Published
Jun 01, 2024
Vol/Issue
94(3-4)
Pages
308-321
Cite This Article
Sukhdeep Kaur, Kiran Bains (2024). Aloe Barbadensis Miller (Aloe Vera). International Journal for Vitamin and Nutrition Research, 94(3-4), 308-321. https://doi.org/10.1024/0300-9831/a000797