journal article Apr 01, 1999

Presenilin is required for activity and nuclear access of Notch in Drosophila

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References
28
[1]
Selkoe, D. J. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol. 8, 447–453 (1998). 10.1016/s0962-8924(98)01363-4
[2]
Levitan, D. & Greenwald, I. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377, 351–354 (1995). 10.1038/377351a0
[3]
Li, X. & Greenwald, I. HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signalling. Proc. Natl Acad. Sci. USA 94, 12204–12209 (1997). 10.1073/pnas.94.22.12204
[4]
Shen, J. et al. Skeletal and CNS defects in Presenilin-1 deficient mice. Cell 89, 629–639 (1997). 10.1016/s0092-8674(00)80244-5
[5]
Wong, P. C. et al. Presenilin 1 is required for Notch1 and Dll1 expression in the paraxial mesoderm. Nature 387, 288–292 (1997). 10.1038/387288a0
[6]
Struhl, G. & Adachi, A. Nuclear access and action of Notch in vivo. Cell 93, 649–660 (1998). 10.1016/s0092-8674(00)81193-9
[7]
Schroeter, E. H., Kisslinger, J. A. & Kopan, R. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393, 381–386 (1998). 10.1038/30756
[8]
Lecourtois, M. & Schweisguth, F. Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos. Curr. Biol. 8, 771–774 (1998). 10.1016/s0960-9822(98)70300-8
[9]
Kidd, S., Lieber, T. & Young, M. W. Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes Dev. 12, 3728–3740 (1998). 10.1101/gad.12.23.3728
[10]
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Saftig, Katleen Craessaerts et al.

Nature 1998 10.1038/34910
[11]
Greenwald, I. LIN-12/Notch signaling: lessons from worms and flies. Genes Dev. 12, 1751–1762 (1998). 10.1101/gad.12.12.1751
[12]
Blaumueller, C. M., Qui, H., Zagouras, P. & Artavanis-Tsakonas, S. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 90, 281–291 (1997). 10.1016/s0092-8674(00)80336-0
[13]
Logeat, F. et al. the Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc. Natl Acad. Sci. USA 95, 8108–8112 (1998). 10.1073/pnas.95.14.8108
[14]
Levitan, D. & Greenwald, I. Effects of SEL-12 presenilin on LIN-12 localization and function in C. elegans. Development 125, 3599–3606 (1998). 10.1242/dev.125.18.3599
[15]
Boulianne, G. L. et al. Cloning and characterization of the Drosophila presenilin homologue. Neuroreport 8, 1025–1029 (1997). 10.1097/00001756-199703030-00041
[16]
Hong, C. S. & Koo, E. H. Isolation and characterization of Drosophila presenilin homolog. Neuroreport 8, 665–668 (1997). 10.1097/00001756-199702100-00017
[17]
Marfany, G. et al. Identification of a Drosophila presenilin homologue: evidence of alternatively spliced forms. J. Neurogenet. 12, 41–45 (1993). 10.3109/01677069809108554
[18]
Struhl, G., Fitzgerald, K. & Greenwald, I. Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 74, 331–45 (1993). 10.1016/0092-8674(93)90424-o
[19]
Menne, T. V. & Klaembt, C. The formation of commissures in the Drosophila CNS depends on the midline cells and on the Notch gene. Development 120, 123–133 (1994). 10.1242/dev.120.1.123
[20]
Blair, S. S. Compartments and appendage development in Drosophila. Bioessays 17, 299–309 (1995). 10.1002/bies.950170406
[21]
Huppert, S. S., Jacobsen, T. L. & Muskavitch, M. Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis. Development 124, 3283–3291 (1997). 10.1242/dev.124.17.3283
[22]
Ye, Y. & Fortini, M. E. Characterization of Drosophila Presenilin and its colocalization with Notch during development. Mech. Dev. 79, 199–211 (1998). 10.1016/s0925-4773(98)00169-5
[23]
Li, X. & Greenwald, I. Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins. Proc. Natl Acad. Sci. USA 95, 7109–7114 (1998). 10.1073/pnas.95.12.7109
[24]
Chou, T. B. & Perrimon, N. Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics 131, 643–653 (1992). 10.1093/genetics/131.3.643
[25]
Golic, K. G. Site-specific recombination between homologous chromosomes in Drosophila. Science 252, 958–961 (1991). 10.1126/science.2035025
[26]
Rulifson, E. J. & Blair, S. S. Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila. Development 121, 2813–2824 (1995). 10.1242/dev.121.9.2813
[27]
Greenwald, I. & Seydoux, G. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature 346, 197–1999 (1990). 10.1038/346197a0
[28]
Heitzler, P. & Simpson, P. Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions. Development 117, 1113–1123 (1993). 10.1242/dev.117.3.1113
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671
Citations
28
References
Details
Published
Apr 01, 1999
Vol/Issue
398(6727)
Pages
522-525
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Cite This Article
Gary Struhl, Iva Greenwald (1999). Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature, 398(6727), 522-525. https://doi.org/10.1038/19091
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