Enhanced expression of PD L1 in cervical intraepithelial neoplasia and cervical cancers

Louisa Mezache; Bernard Paniccia; Angelique Nyinawabera; Gerard J Nuovo

doi:10.1038/modpathol.2015.108

journal article Open Access Dec 01, 2015

Enhanced expression of PD L1 in cervical intraepithelial neoplasia and cervical cancers

Louisa Mezache Bernard Paniccia Angelique Nyinawabera Gerard J Nuovo

Modern Pathology Vol. 28 No. 12 pp. 1594-1602 · Elsevier BV

View at Publisher Save 10.1038/modpathol.2015.108

Topics

No keywords indexed for this article. Browse by subject →

References

24

[1]

zur Hausen "Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis" J Natl Cancer Inst (2000) 10.1093/jnci/92.9.690

[2]

Bosch "The causal relation between human papillomavirus and cervical cancer" J Clin Pathol (2002) 10.1136/jcp.55.4.244

[3]

Stoler "The virology of cervical neoplasia: an HPV-associated malignancy" Cancer J (2003) 10.1097/00130404-200309000-00005

[4]

Nuovo "The role of HPV in gynecologic diseases: an update" Critical Reviews in Clin Lab Sciences (2000) 10.1080/10408360091174204

[5]

Nuovo (1993)

[6]

Chen "Histological ‘progression’ from low (LSIL) to high (HSIL) squamous intraepithelial lesion is an uncommon event and an indication for quality assurance review" Mod Pathol (2010) 10.1038/modpathol.2010.85

[7]

Crum "Accumulation of RNA homologous to human papillomavirus type 16 open reading frames in genital precancers" J Virol (1988) 10.1128/jvi.62.1.84-90.1988

[8]

van den Brule "Nonradioactive RNA in situ hybridization detection of human papillomavirus 16-E7 transcripts in squamous cell carcinomas of the uterine cervix using confocal laser scan microscopy" Am J Pathol (1991)

[9]

Nobbenhuis "Cytological regression and clearance of high-risk human papillomavirus in women with an abnormal cervical smear" Lancet (2001) 10.1016/s0140-6736(01)06809-x

[10]

Paraskevaidis "The role of HPV DNA testing in the follow-up period after treatment for CIN: a systematic review of the literature" Cancer Treat Rev (2004) 10.1016/j.ctrv.2003.07.008

[11]

Trimble "Human papillomavirus 16-associated cervical intraepithelial neoplasia in humans excludes CD8 T cells from dysplastic epithelium" J Immunol (2010) 10.4049/jimmunol.1002756

[12]

Nuovo "Human papillomavirus types and recurrent genital warts" JAMA (1990) 10.1001/jama.1990.03440090057026

[13]

Herweijer "Association of varying number of doses of quadrivalent human papillomavirus vaccine with incidence of condyloma" JAMA (2014) 10.1001/jama.2014.95

[14]

Villa "Immunologic responses following administration of a vaccine targeting human papillomavirus Types 6, 11, 16, and 18" Vaccine (2006) 10.1016/j.vaccine.2006.04.068

[15]

Herbst "Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients" Nature (2014) 10.1038/nature14011

[16]

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Paul C. Tumeh, Christina L. Harview, Jennifer H. Yearley et al.

Nature 2014 10.1038/nature13954

[17]

Xie "Intrahepatic PD-1/PD-L1 up-regulation closely correlates with inflammation and virus replication in patients with chronic HBV infection" Immunol Invest (2009) 10.1080/08820130903062210

[18]

Nuovo (2013)

[19]

Nuovo "Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples" Mod Pathol (2012) 10.1038/modpathol.2012.95

[20]

Monnier-Benoit "Immunohistochemical analysis of CD4+ and CD8+ T-cell subsets in high risk human papillomavirus-associated pre-malignant and malignant lesions of the uterine cervix" Gynecol Oncol (2006) 10.1016/j.ygyno.2005.11.039

[21]

Yang "Increased expression of programmed death (PD)-1 and its ligand PD-L1 correlates with impaired cell-mediated immunity in high-risk human papillomavirus-related cervical intraepithelial neoplasia" Immunology (2013) 10.1111/imm.12101

[22]

Karim "Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma" Clin Cancer Res (2009) 10.1158/1078-0432.ccr-09-1652

[23]

Richart "HPV-DNA in situ hybridization can be used for the quality control of diagnostic biopsies" Obstet Gynecol (1990)

[24]

Wang "microRNAs are biomarkers of oncogenic human papillomavirus infections" Proc Natl Acad Sci USA (2014) 10.1073/pnas.1401430111

Cited By

264

The Prognostic Values of HPV Genotypes and Tumor PD-L1 Expression in Patients With HPV-associated Endocervical Adenocarcinoma

Feng Zhou, Hao Chen · 2021

American Journal of Surgical Pathol...

The combined action of monocytic myeloid‐derived suppressor cells and mucosal‐associated invariant T cells promotes the progression of cervical cancer

Zhimin Lu, Mengting Zhu · 2020

International Journal of Cancer

Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels

A. M. Heeren, J. Rotman · 2019

Journal for ImmunoTherapy of Cancer

Metrics

264

Citations

24

References

Details

Published: Dec 01, 2015
Vol/Issue: 28(12)
Pages: 1594-1602
License: View

Authors

Angelique Nyinawabera

G

Gerard J Nuovo

Cite This Article

Louisa Mezache, Bernard Paniccia, Angelique Nyinawabera, et al. (2015). Enhanced expression of PD L1 in cervical intraepithelial neoplasia and cervical cancers. Modern Pathology, 28(12), 1594-1602. https://doi.org/10.1038/modpathol.2015.108

Enhanced expression of PD L1 in cervical intraepithelial neoplasia and cervical cancers

You May Also Like