journal article Apr 19, 2011

Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search

View at Publisher Save 10.1038/mp.2011.32
Topics

No keywords indexed for this article. Browse by subject →

References
69
[1]
Peper JS, Brouwer RM, Boomsma DI, Kahn RS, Hulshoff Pol HE . Genetic influences on human brain structure: a review of brain imaging studies in twins. Hum Brain Mapp 2007; 28: 464–473. 10.1002/hbm.20398
[2]
Kremen WS, Prom-Wormley E, Panizzon MS, Eyler LT, Fischl B, Neale MC et al. Genetic and environmental influences on the size of specific brain regions in midlife: the VETSA MRI study. Neuroimage 2010; 49: 1213–1223. 10.1016/j.neuroimage.2009.09.043
[3]
Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE . Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 2007; 39: 17–23. 10.1038/ng1934
[4]
Shaw P, Lerch JP, Pruessner JC, Taylor KN, Rose AB, Greenstein D et al. Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. Lancet Neurol 2007; 6: 494–500. 10.1016/s1474-4422(07)70106-0
[5]
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions

Irving I. Gottesman, Todd D. Gould

American Journal of Psychiatry 2003 10.1176/appi.ajp.160.4.636
[6]
Harris GJ, Pearlson GD, Peyser CE, Aylward EH, Roberts J, Barta PE et al. Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington′s disease. Ann Neurol 1992; 31: 69–75. 10.1002/ana.410310113
[7]
Rosas HD, Goodman J, Chen YI, Jenkins BG, Kennedy DN, Makris N et al. Striatal volume loss in HD as measured by MRI and the influence of CAG repeat. Neurology 2001; 57: 1025–1028. 10.1212/wnl.57.6.1025
[8]
Thomas M, Jankovic J . Neurodegenerative disease and iron storage in the brain. Curr Opin Neurol 2004; 17: 437–442. 10.1097/01.wco.0000137534.61244.d1
[9]
Curtis AR, Fey C, Morris CM, Bindoff LA, Ince PG, Chinnery PF et al. Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease. Nat Genet 2001; 28: 350–354. 10.1038/ng571
[10]
Appenzeller S, Schirmacher A, Halfter H, Baumer S, Pendziwiat M, Timmerman V et al. Autosomal-dominant striatal degeneration is caused by a mutation in the phosphodiesterase 8B gene. Am J Hum Genet 2010; 86: 83–87. 10.1016/j.ajhg.2009.12.003
[11]
Kuhlenbaumer G, Ludemann P, Schirmacher A, De Vriendt E, Hunermund G, Young P et al. Autosomal dominant striatal degeneration (ADSD): clinical description and mapping to 5q13-5q14. Neurology 2004; 62: 2203–2208. 10.1212/01.wnl.0000130485.89814.10
[12]
Sheline YI . Neuroimaging studies of mood disorder effects on the brain. Biol Psychiatry 2003; 54: 338–352. 10.1016/s0006-3223(03)00347-0
[13]
Madsen SK, Ho AJ, Hua X, Saharan PS, Toga AW, Jack Jr CR et al. 3D maps localize caudate nucleus atrophy in 400 AD, MCI, and healthy elderly subjects. Neurobiol Aging 2010; 31: 1312–1325. 10.1016/j.neurobiolaging.2010.05.002
[14]
Castellanos FX, Giedd JN, Eckburg P, Marsh WL, Vaituzis AC, Kaysen D et al. Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder. Am J Psychiatry 1994; 151: 1791–1796. 10.1176/ajp.151.12.1791
[15]
Goldman AL, Pezawas L, Mattay VS, Fischl B, Verchinski BA, Zoltick B et al. Heritability of brain morphology related to schizophrenia: a large-scale automated magnetic resonance imaging segmentation study. Biol Psychiatry 2008; 63: 475–483. 10.1016/j.biopsych.2007.06.006
[16]
Wright IC, Rabe-Hesketh S, Woodruff PW, David AS, Murray RM, Bullmore ET . Meta-analysis of regional brain volumes in schizophrenia. Am J Psychiatry 2000; 157: 16–25. 10.1176/ajp.157.1.16
[17]
The New Genomics: Global Views of Biology

Eric S. Lander

Science 1996 10.1126/science.274.5287.536
[18]
Hickie IB, Naismith SL, Ward PB, Scott EM, Mitchell PB, Schofield PR et al. Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression. J Affect Disord 2007; 98: 137–142. 10.1016/j.jad.2006.07.010
[19]
Bartres-Faz D, Junque C, Serra-Grabulosa JM, Lopez-Alomar A, Moya A, Bargallo N et al. Dopamine DRD2 Taq I polymorphism associates with caudate nucleus volume and cognitive performance in memory impaired subjects. Neuroreport 2002; 13: 1121–1125. 10.1097/00001756-200207020-00010
[20]
Durston S, Fossella JA, Casey BJ, Hulshoff Pol HE, Galvan A, Schnack HG et al. Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Mol Psychiatry 2005; 10: 678–685. 10.1038/sj.mp.4001649
[21]
Glatt CE, Freimer NB . Association analysis of candidate genes for neuropsychiatric disease: the perpetual campaign. Trends Genet 2002; 18: 307–312. 10.1016/s0168-9525(02)02670-7
[22]
Freimer N, Sabatti C . The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology. Nat Genet 2004; 36: 1045–1051. 10.1038/ng1433
[23]
Stein JL, Hua X, Morra JH, Lee S, Hibar DP, Ho AJ et al. Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage 2010; 51: 542–554. 10.1016/j.neuroimage.2010.02.068
[24]
Petersen RC . Aging, mild cognitive impairment, and Alzheimer's disease. Neurol Clin 2000; 18: 789–806. 10.1016/s0733-8619(05)70226-7
[25]
Medland SE, Nyholt DR, Painter JN, McEvoy BP, McRae AF, Zhu G et al. Common variants in the trichohyalin gene are associated with straight hair in Europeans. Am J Hum Genet 2009; 85: 750–755. 10.1016/j.ajhg.2009.10.009
[26]
Mazziotta J, Toga A, Evans A, Fox P, Lancaster J, Zilles K et al. A probabilistic atlas and reference system for the human brain: International Consortium for Brain Mapping (ICBM). Philos Trans R Soc Lond B Biol Sci 2001; 356: 1293–1322. 10.1098/rstb.2001.0915
[27]
Morra JH, Tu Z, Apostolova LG, Green AE, Avedissian C, Madsen SK et al. Validation of a fully automated 3D hippocampal segmentation method using subjects with Alzheimer's disease mild cognitive impairment, and elderly controls. Neuroimage 2008; 43: 59–68. 10.1016/j.neuroimage.2008.07.003
[28]
Looi JC, Lindberg O, Liberg B, Tatham V, Kumar R, Maller J et al. Volumetrics of the caudate nucleus: reliability and validity of a new manual tracing protocol. Psychiatry Res 2008; 163: 279–288. 10.1016/j.pscychresns.2007.07.005
[29]
Duvernoy HM . The Human Brain: Surface, Three-Dimensional Sectional Anatomy with MRI, and Blood Supply. 2nd edn. Springer-Verlag Wien: New York, 1999. 10.1007/978-3-7091-6792-2
[30]
Neale MC, Cardon LR . Methodology for Genetic Studies of Twins and Families. Kluwer Academic: Dordrecht, The Netherlands, 1992. 10.1007/978-94-015-8018-2
[31]
Chiang MC, Barysheva M, Shattuck DW, Lee AD, Madsen SK, Avedissian C et al. Genetics of brain fiber architecture and intellectual performance. J Neurosci 2009; 29: 2212–2224. 10.1523/jneurosci.4184-08.2009
[32]
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

Shaun Purcell, Benjamin Neale, Kathe Todd-Brown et al.

The American Journal of Human Genetics 2007 10.1086/519795
[33]
A unified mixed-model method for association mapping that accounts for multiple levels of relatedness

Jianming Yu, Gael Pressoir, William H Briggs et al.

Nature Genetics 2006 10.1038/ng1702
[34]
Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ et al. Efficient control of population structure in model organism association mapping. Genetics 2008; 178: 1709–1723. 10.1534/genetics.107.080101
[35]
Classical twin studies and beyond

Dorret Boomsma, Andreas Busjahn, Leena Peltonen

Nature Reviews Genetics 2002 10.1038/nrg932
[36]
Bacanu SA, Devlin B, Roeder K . The power of genomic control. Am J Hum Genet 2000; 66: 1933–1944. 10.1086/302929
[37]
Morey RA, Petty CM, Xu Y, Hayes JP, Wagner II HR, Lewis DV et al. A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes. Neuroimage 2009; 45: 855–866. 10.1016/j.neuroimage.2008.12.033
[38]
Morey RA, Selgrade ES, Wagner II HR, Huettel SA, Wang L, McCarthy G . Scan-rescan reliability of subcortical brain volumes derived from automated segmentation. Hum Brain Mapp 2010; 31: 1751–1762. 10.1002/hbm.20973
[39]
Ryu S, Mahler J, Acampora D, Holzschuh J, Erhardt S, Omodei D et al. Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development. Curr Biol 2007; 17: 873–880. 10.1016/j.cub.2007.04.003
[40]
Struyf J, Dobrin S, Page D . Combining gene expression, demographic and clinical data in modeling disease: a case study of bipolar disorder and schizophrenia. BMC Genomics 2008; 9: 531. 10.1186/1471-2164-9-531
[41]
Kobayashi T, Gamanuma M, Sasaki T, Yamashita Y, Yuasa K, Kotera J et al. Molecular comparison of rat cyclic nucleotide phosphodiesterase 8 family: unique expression of PDE8B in rat brain. Gene 2003; 319: 21–31. 10.1016/s0378-1119(03)00809-6
[42]
Nicola SM, Surmeier J, Malenka RC . Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens. Annu Rev Neurosci 2000; 23: 185–215. 10.1146/annurev.neuro.23.1.185
[43]
Girault JA, Greengard P . The neurobiology of dopamine signaling. Arch Neurol 2004; 61: 641–644. 10.1001/archneur.61.5.641
[44]
Menniti FS, Faraci WS, Schmidt CJ . Phosphodiesterases in the CNS: targets for drug development. Nat Rev Drug Discov 2006; 5: 660–670. 10.1038/nrd2058
[45]
Wong ML, Whelan F, Deloukas P, Whittaker P, Delgado M, Cantor RM et al. Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response. Proc Natl Acad Sci USA 2006; 103: 15124–15129. 10.1073/pnas.0602795103
[46]
Perez-Torres S, Cortes R, Tolnay M, Probst A, Palacios JM, Mengod G . Alterations on phosphodiesterase type 7 and 8 isozyme mRNA expression in Alzheimer's disease brains examined by in situ hybridization. Exp Neurol 2003; 182: 322–334. 10.1016/s0014-4886(03)00042-6
[47]
Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009; 41: 56–65. 10.1038/ng.291
[48]
Levey AI, Hersch SM, Rye DB, Sunahara RK, Niznik HB, Kitt CA et al. Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. Proc Natl Acad Sci USA 1993; 90: 8861–8865. 10.1073/pnas.90.19.8861
[49]
Mozley LH, Gur RC, Mozley PD, Gur RE . Striatal dopamine transporters and cognitive functioning in healthy men and women. Am J Psychiatry 2001; 158: 1492–1499. 10.1176/appi.ajp.158.9.1492
[50]
Nieoullon A . Dopamine and the regulation of cognition and attention. Prog Neurobiol 2002; 67: 53–83. 10.1016/s0301-0082(02)00011-4

Showing 50 of 69 references

Metrics
40
Citations
69
References
Details
Published
Apr 19, 2011
Vol/Issue
16(9)
Pages
927-937
License
View
Cite This Article
J L Stein, D P Hibar, S K Madsen, et al. (2011). Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search. Molecular Psychiatry, 16(9), 927-937. https://doi.org/10.1038/mp.2011.32