journal article Open Access Jan 01, 2015

Treatment of CD33-directed Chimeric Antigen Receptor-modified T Cells in One Patient With Relapsed and Refractory Acute Myeloid Leukemia

Molecular Therapy Vol. 23 No. 1 pp. 184-191 · Elsevier BV
View at Publisher Save 10.1038/mt.2014.164
Topics

No keywords indexed for this article. Browse by subject →

References
34
[1]
Döhner "Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet" Blood (2010) 10.1182/blood-2009-07-235358
[2]
Creutzig "Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel" Blood (2012) 10.1182/blood-2012-03-362608
[3]
Tettamanti "Acute myeloid leukemia and novel biological treatments: monoclonal antibodies and cell-based gene-modified immune effectors" Immunol Lett (2013) 10.1016/j.imlet.2013.09.013
[4]
Pearce "AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML" Blood (2006) 10.1182/blood-2005-06-2325
[5]
Nakahata "Cell surface antigen expression in human erythroid progenitors: erythroid and megakaryocytic markers" Leuk Lymphoma (1994) 10.3109/10428199409049629
[6]
Taussig "Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia" Blood (2005) 10.1182/blood-2005-03-1072
[7]
Griffin "A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cells" Leuk Res (1984) 10.1016/0145-2126(84)90001-8
[8]
Dinndorf "Expression of normal myeloid-associated antigens by acute leukemia cells" Blood (1986) 10.1182/blood.v67.4.1048.1048
[9]
Kung Sutherland "SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML" Blood (2013) 10.1182/blood-2013-03-491506
[10]
Nand "A phase 2 trial of azacitidine and gemtuzumab ozogamicin therapy in older patients with acute myeloid leukemia" Blood (2013) 10.1182/blood-2013-06-506592
[11]
Rowe "Gemtuzumab ozogamicin in acute myeloid leukemia: a remarkable saga about an active drug" Blood (2013) 10.1182/blood-2013-03-490482
[12]
Hinrichs "Exploiting the curative potential of adoptive T-cell therapy for cancer" Immunol Rev (2014) 10.1111/imr.12132
[13]
Grupp "Chimeric antigen receptor-modified T cells for acute lymphoid leukemia" N Engl J Med (2013) 10.1056/nejmoa1215134
[14]
Kalos "T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia" Sci Transl Med (2011) 10.1126/scitranslmed.3002842
[15]
Kochenderfer "B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells" Blood (2012) 10.1182/blood-2011-10-384388
[16]
Dutour "In vitro and in vivo antitumor effect of anti-CD33 chimeric receptor-expressing EBV-CTL against CD33 acute myeloid leukemia" Adv Hematol (2012) 10.1155/2012/683065
[17]
Marin "Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors" Haematologica (2010) 10.3324/haematol.2010.026310
[18]
Pizzitola "Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo" Leukemia (2014) 10.1038/leu.2014.62
[19]
Sievers "Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse" J Clin Oncol (2001) 10.1200/jco.2001.19.13.3244
[20]
Kharfan-Dabaja "Gemtuzumab ozogamicin for treatment of newly diagnosed acute myeloid leukaemia: a systematic review and meta-analysis" Br J Haematol (2013) 10.1111/bjh.12528
[21]
Wang "CIK cells from recurrent or refractory AML patients can be efficiently expanded in vitro and used for reduction of leukemic blasts in vivo" Exp Hematol (2013) 10.1016/j.exphem.2012.10.014
[22]
Laszlo "The past and future of CD33 as therapeutic target in acute myeloid leukemia" Blood Rev (2014) 10.1016/j.blre.2014.04.001
[23]
McKoy "Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): an overview from the research on adverse drug events and reports (RADAR) project" Leuk Res (2007) 10.1016/j.leukres.2006.07.005
[24]
Larson "Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence" Cancer (2005) 10.1002/cncr.21326
[25]
Maniecki "Is hepatotoxicity in patients treated with gemtuzumabozogamicin due to specific targeting of hepatocytes?" Leuk Res (2011) 10.1016/j.leukres.2011.01.025
[26]
Nishimura "In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity" Blood (2008) 10.1182/blood-2007-06-092817
[27]
Hernández-Caselles "A study of CD33 (SIGLEC-3) antigen expression and function on activated human T and NK cells: two isoforms of CD33 are generated by alternative splicing" J Leukoc Biol (2006) 10.1189/jlb.0205096
[28]
Hauswirth "Expression of the target receptor CD33 in CD34+/CD38-/CD123+ AML stem cells" Eur J Clin Invest (2007) 10.1111/j.1365-2362.2007.01746.x
[29]
Cowan "Antibody-based therapy of acute myeloid leukemia with gemtuzumab ozogamicin" Front Biosci (Landmark Ed) (2013) 10.2741/4181
[30]
Jedema "Internalization and cell cycle-dependent killing of leukemic cells by gemtuzumab ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity" Leukemia (2004) 10.1038/sj.leu.2403205
[31]
Landau "Clonal evolution in hematological malignancies and therapeutic implications" Leukemia (2014) 10.1038/leu.2013.248
[32]
Zeijlemaker "Tumor heterogeneity makes AML a “moving target” for detection of residual disease" Cytometry B Clin Cytom (2014) 10.1002/cyto.b.21134
[33]
Introna "Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study" Haematologica (2007) 10.3324/haematol.11132
[34]
Linn "The anti-tumour activity of allogeneic cytokine-induced killer cells in patients who relapse after allogeneic transplant for haematological malignancies" Bone Marrow Transplant (2012) 10.1038/bmt.2011.202
Metrics
376
Citations
34
References
Details
Published
Jan 01, 2015
Vol/Issue
23(1)
Pages
184-191
License
View
Cite This Article
Quan-shun Wang, Yao Wang, Hai-yan Lv, et al. (2015). Treatment of CD33-directed Chimeric Antigen Receptor-modified T Cells in One Patient With Relapsed and Refractory Acute Myeloid Leukemia. Molecular Therapy, 23(1), 184-191. https://doi.org/10.1038/mt.2014.164