Topics

No keywords indexed for this article. Browse by subject →

References
37
[1]
Milstein, C. & Rada, C. The maturation of the antibody response. in Immunoglobulin Genes edn. 2 (eds. Honjo, T. & Alt, F.W.) 57–81 (Academic Press, London, 1995). 10.1016/b978-012053640-5/50006-9
[2]
Rajewsky, K. Clonal selection and learning in the antibody system. Nature 381, 751–758 (1996). 10.1038/381751a0
[3]
Neuberger, M.S. Antibodies: a paradigm for the evolution of molecular recognition. Biochem. Soc. Trans. 30, 341–350 (2002). 10.1042/bst0300341
[4]
Tonegawa, S. Somatic generation of antibody diversity. Nature 302, 575–581 (1983). 10.1038/302575a0
[5]
Alzari, P.M. et al. Three-dimensional structure determination of an anti-2-phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response. EMBO J. 9, 3807–3814 (1990). 10.1002/j.1460-2075.1990.tb07598.x
[6]
Mizutani, R. et al. Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl) acetate. J. Mol. Biol. 254, 208–222 (1995). 10.1006/jmbi.1995.0612
[7]
Yuhasz, S.C., Parry, C., Strand, M. & Amzel, L.M. Structural analysis of affinity maturation: the three-dimensional structures of complexes of an anti-nitrophenol antibody. Mol. Immunol. 32, 1143–1155 (1995). 10.1016/0161-5890(95)00063-1
[8]
Wedemayer, G.J., Patten, P.A., Wang, L.H., Schultz, P.G. & Stevens, R.C. Structural insights into the evolution of an antibody combining site. Science 276, 1665–1669 (1997). 10.1126/science.276.5319.1665
[9]
Furukawa, K., Akasaka-Furukane, A., Shirai, H., Nakmura, H. & Azuma, T. Junctional amino acids determine the maturation pathway of an antibody. Immunity 11, 329–338 (1999). 10.1016/s1074-7613(00)80108-9
[10]
Manivel, V., Sahoo, N.C., Salunke, D.M. & Rao, K.V.S. Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site. Immunity 13, 611–620 (2000). 10.1016/s1074-7613(00)00061-3
[11]
MacCallum, R.M., Martin, A.C.R. & Thornton, J.M. Antibody–antigen interactions: contact analysis and binding site topography. J. Mol. Biol. 262, 732–745 (1996). 10.1006/jmbi.1996.0548
[12]
Sundberg, E.J. & Mariuzza, R.A. Molecular recognition in antigen–antibody complexes. Adv. Protein Chem. 61, 119–160 (2002). 10.1016/s0065-3233(02)61004-6
[13]
Newman, M.A., Mainhart, C.R., Mallet, C.P., Lavoie, T.B. & Smith-Gill, S.J. Patterns of antibody specificity during the BALB/c immune response to hen eggwhite lysozyme. J. Immunol. 149, 3260–3272 (1992). 10.4049/jimmunol.149.10.3260
[14]
Lavoie, T.B. et al. Structural differences among monoclonal antibodies with distinct fine specificities and kinetic properties. Mol. Immunol. 36, 1189–1205 (1999). 10.1016/s0161-5890(99)00130-3
[15]
Kondo, H., Shiroishi, M., Matsushima, M., Tsumoto, K. & Kumagai, I. Crystal structure of anti-hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. J. Biol. Chem. 274, 27623–27631 (1999). 10.1074/jbc.274.39.27623
[16]
Li, Y., Li, H., Smith-Gill, S.J. & Mariuzza, R.A. Three-dimensional structure of the free and antigen-bound Fab from monoclonal anti-lysozyme antibody HyHEL-63. Biochemistry 39, 6296–6309 (2000). 10.1021/bi000054l
[17]
Pons, J., Rajpal, A. & Kirsch, J.F. Energetic analysis of an antigen/antibody interface: alanine scanning mutagenesis and double mutant cycles on the HyHEL-10/lysozyme interaction. Protein Sci. 8, 958–968 (1999). 10.1110/ps.8.5.958
[18]
Li, Y., Urrutia, M., Smith-Gill, S.J. & Mariuzza, R.A. Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen. Biochemistry 42, 11–22 (2003). 10.1021/bi020589+
[19]
Structural basis of macromolecular recognition

Shoshana J Wodak, Joël Janin

Advances in Protein Chemistry 2002 10.1016/s0065-3233(02)61001-0
[20]
Yang, P.L. & Schultz, P.G. Mutational analysis of the affinity maturation of antibody 48G7. J. Mol. Biol. 294, 1191–1201 (1999). 10.1006/jmbi.1999.3197
[21]
The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht

Loredana Lo Conte, Cyrus Chothia, Joël Janin

Journal of Molecular Biology 1999 10.1006/jmbi.1998.2439
[22]
Shape Complementarity at Protein/Protein Interfaces

Michael C. Lawrence, Peter M. Colman

Journal of Molecular Biology 1993 10.1006/jmbi.1993.1648
[23]
Sundberg, E.J. et al. Estimation of the hydrophobic effect in an antigen–antibody protein–protein interface. Biochemistry 39, 15375–15387 (2000). 10.1021/bi000704l
[24]
Solvation energy in protein folding and binding

David Eisenberg, Andrew D. McLachlan

Nature 1986 10.1038/319199a0
[25]
Anatomy of hot spots in protein interfaces

Andrew A Bogan, Kurt S Thorn

Journal of Molecular Biology 1998 10.1006/jmbi.1998.1843
[26]
Ramanadham, M., Sieker, L.C. & Jensen, L.H. Refinement of triclinic lysozyme: II. The method of stereochemically restrained least squares. Acta Crystallogr. B 46, 63–69 (1990). 10.1107/s0108768189009195
[27]
Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme.

K.P. Wilson, B.A. Malcolm, B.W. Matthews

Journal of Biological Chemistry 1992 10.1016/s0021-9258(19)50095-3
[28]
Madhusudan, Kodandapani, R. & Vijayan, M. Protein hydration and water structure: X-ray analysis of a closely packed protein crystal with very low solvent content. Acta Crystallogr. D 49, 234–245 (1993). 10.1107/s090744499200653x
[29]
A Hot Spot of Binding Energy in a Hormone-Receptor Interface

Tim Clackson, James A. Wells

Science 1995 10.1126/science.7529940
[30]
Tomlinson, I.M. et al. The imprint of somatic hypermutation on the repertoire of human germline genes. J. Mol. Biol. 256, 813–817 (1996). 10.1006/jmbi.1996.0127
[31]
Dall'Acqua, W. et al. A mutational analysis of binding interactions in an antigen–antibody protein–protein complex. Biochemistry 37, 7981–7991 (1998). 10.1021/bi980148j
[32]
[20] Processing of X-ray diffraction data collected in oscillation mode

Zbyszek Otwinowski, Wladek Minor

Methods in Enzymology 1997 10.1016/s0076-6879(97)76066-x
[33]
Collaborative Computational Project, Number 4. CCP4 site: programs for protein crystallography. Acta Crystallogr. D 50, 760–763 (1994).
[34]
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

A. T. Brünger, P. D. Adams, G. M. Clore et al.

Acta Crystallographica Section D Biological Crysta... 1998 10.1107/s0907444998003254
[35]
Roussel, A. & Cambillau, C. TURBO-FRODO. in Silicon Graphics Partners Directory 77–78 (Silicon Graphics, Mountain View, California, 1989).
[36]
AMoRe: an automated package for molecular replacement

J. Navaza

Acta Crystallographica Section A Foundations of Cr... 1994 10.1107/s0108767393007597
[37]
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

Anthony Nicholls, Kim A. Sharp, Barry Honig

Proteins: Structure, Function, and Bioinformatics 1991 10.1002/prot.340110407
Cited By
143
How repertoire data are changing antibody science

Claire Marks, Charlotte M. Deane · 2020

Journal of Biological Chemistry
Computer-aided antibody design

D. Kuroda, H. Shirai · 2012

"Protein Engineering, Design and Se...
Proceedings of the National Academy...
Proceedings of the National Academy...
Proceedings of the National Academy...
Metrics
143
Citations
37
References
Details
Published
May 12, 2003
Vol/Issue
10(6)
Pages
482-488
License
View
Cite This Article
Yili Li, Hongmin Li, Feng Yang, et al. (2003). X-ray snapshots of the maturation of an antibody response to a protein antigen. Nature Structural & Molecular Biology, 10(6), 482-488. https://doi.org/10.1038/nsb930
Related

You May Also Like

Announcing the worldwide Protein Data Bank

Helen Berman, Kim Henrick · 2003

2,657 citations

From Levinthal to pathways to funnels

Ken A. Dill, Hue Sun Chan · 1997

1,964 citations

Experimentally determined hydrophobicity scale for proteins at membrane interfaces

William C. Wimley, Stephen H. White · 1996

1,473 citations

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

Dagmar E Ehrnhoefer, Jan Bieschke · 2008

1,310 citations