Maternal and foetal complications of pregestational and gestational diabetes: a descriptive, retrospective cohort study

Miriam Oros Ruiz; Daniel Perejón López; Catalina Serna Arnaiz; Júlia Siscart Viladegut; Joan Àngel Baldó; Joaquim Sol

doi:10.1038/s41598-024-59465-x

journal article Open Access Apr 19, 2024

Maternal and foetal complications of pregestational and gestational diabetes: a descriptive, retrospective cohort study

Miriam Oros Ruiz Daniel Perejón López Catalina Serna Arnaiz Júlia Siscart Viladegut Joan Àngel Baldó Joaquim Sol

Scientific Reports Vol. 14 No. 1 · Springer Science and Business Media LLC

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Abstract

AbstractGestational diabetes is characterized by hyperglycaemia diagnosed during pregnancy. Gestational and pregestational diabetes can have deleterious effects during pregnancy and perinatally. The baby's weight is frequently above average and might reach macrosomia (≥ 4 kg), which can reduce pregnancy time causing preterm births, and increase foetal-pelvic disproportion which often requires delivery by caesarean section. Foetal-pelvic disproportion due to the baby’s weight can also cause foetal distress resulting in lower Apgar scores. To analyse the association between pregestational and gestational diabetes with maternal and foetal risk. We conducted a retrospective cohort study in women pregnant between 2012 and 2018 in the region of Lleida. Regression coefficients and 95% confidence intervals (CI) were used. The multivariate analysis showed statistically significant associations between pregestational diabetes and: prematurity (OR 2.4); caesarean section (OR 1.4); moderate (OR 1.3), high (OR 3.3) and very high (OR 1.7) risk pregnancies; and birth weight ≥ 4000 g (macrosomia) (OR 1.7). In getational diabetes the multivariate analysis show significant association with: caesarean section (OR 1.5); moderate (OR 1.7), high (OR 1.7) and very high (OR 1.8) risk pregnancies and lower 1-minuto Apgar score (OR 1.5). Pregestational and gestational diabetes increase: pregnancy risk, caesarean sections, prematurity, low Apgar scores, and macrosomia.

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Details

Published: Apr 19, 2024
Vol/Issue: 14(1)
License: View

Authors

Catalina Serna Arnaiz

J

Júlia Siscart Viladegut

Metabolic Physiopathology Research Group, Experimental Medicine Department, Lleida University-Lleida Biochemical Research Institute (UdL-IRBLleida), Lleida, Spain; Institut Català de la Salut, Atenció Primària, Lleida, Spain; Research Support Unit Lleida, Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Lleida, Spain

Cite This Article

Miriam Oros Ruiz, Daniel Perejón López, Catalina Serna Arnaiz, et al. (2024). Maternal and foetal complications of pregestational and gestational diabetes: a descriptive, retrospective cohort study. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-59465-x

Maternal and foetal complications of pregestational and gestational diabetes: a descriptive, retrospective cohort study

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