Association between allergic conditions and risk of prostate cancer: A Prisma-Compliant Systematic Review and Meta-Analysis

Jianguo Zhu; Jukun Song; Zezhen Liu; Jin Han; Heng Luo; Yunlin Liu; Zhenyu Jia; Yuanbo Dong; Wei Zhang; Funeng Jiang; Chinlee Wu; Zaolin Sun; Weide Zhong

doi:10.1038/srep35682

journal article Open Access Oct 21, 2016

Association between allergic conditions and risk of prostate cancer: A Prisma-Compliant Systematic Review and Meta-Analysis

Jianguo Zhu

Jukun Song

Zezhen Liu Jin Han

Heng Luo

Yunlin Liu Zhenyu Jia Yuanbo Dong Wei Zhang

Funeng Jiang Chinlee Wu Zaolin Sun Weide Zhong

Scientific Reports Vol. 6 No. 1 · Springer Science and Business Media LLC

View at Publisher Save 10.1038/srep35682

Abstract

AbstractAssociation between allergic conditions and prostate cancer risk has been investigated for many years. However, the results from available evidence for the association are inconsistent. We conducted a meta-analysis to evaluate the relationship between allergic conditions (asthma, atopy, hay fever and “any allergy”) and risk of prostate cancer. The PubMed and Embase databases were searched to screen observational studies meeting our meta-analysis criteria. Study selection and data extraction from included studies were independently performed by two authors. Twenty studies were considered eligible involving 5 case-control studies and 15 cohort studies. The summary relative risk (RR) for developing prostate cancer risk was 1.04 (95%CI: 0.92–1.17) for asthma, and 1.25 (95%CI: 0.74–2.10) for atopy, 1.04 (95%CI: 0.99–1.09) for hay fever, 0.96 (95%CI: 0.86–1.06) for any allergy. In the Subgroup and sensitivity analysis, similar results were produced. Little evidence of publication bias was observed. The present meta-analysis of observational studies indicates that no indication of an association between allergic conditions and risk of prostate cancer was found, and the meta-analysis does not support neither the original hypothesis of an overall cancer protective effect of allergic conditions, nor that of an opposite effect in the development of prostate cancer.

Topics

No keywords indexed for this article. Browse by subject →

References

55

[1]

Siegel, R. L. et al. Cancer statistics for Hispanics/Latinos. CA: a cancer journal for clinicians 65, 457–480, doi: 10.3322/caac.21314 (2015). 10.3322/caac.21314

[2]

Global cancer statistics

Ahmedin Jemal, Freddie Bray, Melissa M. Center et al.

CA: A Cancer Journal for Clinicians 2011 10.3322/caac.20107

[3]

Zhu, Y., Wang, H. K., Qu, Y. Y. & Ye, D. W. Prostate cancer in East Asia: evolving trend over the last decade. Asian journal of andrology 17, 48–57, doi: 10.4103/1008-682X.132780 (2015). 10.4103/1008-682x.132780

[4]

Allott, E. H., Masko, E. M. & Freedland, S. J. Obesity and prostate cancer: weighing the evidence. Eur Urol 63, 800–809, doi: 10.1016/j.eururo.2012.11.013 (2013). 10.1016/j.eururo.2012.11.013

[5]

Diet and prostate cancer: mechanisms of action and implications for chemoprevention

Vasundara Venkateswaran, Laurence H. Klotz

Nature Reviews Urology 2010 10.1038/nrurol.2010.102

[6]

Bostwick, D. G. et al. Human prostate cancer risk factors. Cancer 101, 2371–2490, doi: 10.1002/cncr.20408 (2004). 10.1002/cncr.20408

[7]

Hsing, A. W. & Chokkalingam, A. P. Prostate cancer epidemiology. Frontiers in bioscience: a journal and virtual library 11, 1388–1413 (2006). 10.2741/1891

[8]

Gurel, B. et al. Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 23, 847–856, doi: 10.1158/1055-9965.EPI-13-1126 (2014). 10.1158/1055-9965.epi-13-1126

[9]

Inflammation in prostate carcinogenesis

Angelo M. De Marzo, Elizabeth A. Platz, Siobhan Sutcliffe et al.

Nature Reviews Cancer 2007 10.1038/nrc2090

[10]

Wang, H. et al. Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung and colorectum. International journal of cancer. Journal international du cancer 119, 695–701, doi: 10.1002/ijc.21883 (2006). 10.1002/ijc.21883

[11]

Mills, P. K., Beeson, W. L., Fraser, G. E. & Phillips, R. L. Allergy and cancer: organ site-specific results from the Adventist Health Study. American journal of epidemiology 136, 287–295 (1992). 10.1093/oxfordjournals.aje.a116494

[12]

Kallen, B., Gunnarskog, J. & Conradson, T. B. Cancer risk in asthmatic subjects selected from hospital discharge registry. The European respiratory journal 6, 694–697 (1993). 10.1183/09031936.93.06050694

[13]

Vesterinen, E., Pukkala, E., Timonen, T. & Aromaa, A. Cancer incidence among 78,000 asthmatic patients. International journal of epidemiology 22, 976–982 (1993). 10.1093/ije/22.6.976

[14]

Eriksson, N. E., Holmen, A., Hogstedt, B., Mikoczy, Z. & Hagmar, L. A prospective study of cancer incidence in a cohort examined for allergy. Allergy 50, 718–722 (1995). 10.1111/j.1398-9995.1995.tb01212.x

[15]

Talbot-Smith, A., Fritschi, L., Divitini, M. L., Mallon, D. F. & Knuiman, M. W. Allergy, atopy, and cancer: a prospective study of the 1981 Busselton cohort. American journal of epidemiology 157, 606–612 (2003). 10.1093/aje/kwg020

[16]

Turner, M. C. et al. Cancer mortality among US men and women with asthma and hay fever. American journal of epidemiology 162, 212–221, doi: 10.1093/aje/kwi193 (2005). 10.1093/aje/kwi193

[17]

Gonzalez-Perez, A., Fernandez-Vidaurre, C., Rueda, A., Rivero, E. & Garcia Rodriguez, L. A. Cancer incidence in a general population of asthma patients. Pharmacoepidemiol Drug Saf 15, 131–138, doi: 10.1002/pds.1163 (2006). 10.1002/pds.1163

[18]

Vena, J. E. et al. Allergy-related diseases and cancer: an inverse association. American journal of epidemiology 122, 66–74 (1985). 10.1093/oxfordjournals.aje.a114087

[19]

McWhorter, W. P. Allergy and risk of cancer. A prospective study using NHANESI followup data. Cancer 62, 451–455 (1988). 10.1002/1097-0142(19880715)62:2<451::aid-cncr2820620234>3.0.co;2-d

[20]

Vojtechova, P. & Martin, R. M. The association of atopic diseases with breast, prostate, and colorectal cancers: a meta-analysis. Cancer causes & control: CCC 20, 1091–1105, doi: 10.1007/s10552-009-9334-y (2009). 10.1007/s10552-009-9334-y

[21]

Ohrui, T. et al. Risk of prostate cancer in older Japanese asthmatics. Journal of the American Geriatrics Society 50, 202 (2002). 10.1046/j.1532-5415.2002.50034.x

[22]

Lightfoot, N. et al. Medical history, sexual, and maturational factors and prostate cancer risk. Ann Epidemiol 14, 655–662, doi: 10.1016/j.annepidem.2003.11.006 (2004). 10.1016/j.annepidem.2003.11.006

[23]

Hemminki, K. et al. Risk of cancer in patients with medically diagnosed hay fever or allergic rhinitis. International journal of cancer. Journal international du cancer 135, 2397–2403, doi: 10.1002/ijc.28873 (2014). 10.1002/ijc.28873

[24]

Ji, J. et al. Cancer risk in hospitalised asthma patients. British journal of cancer 100, 829–833, doi: 10.1038/sj.bjc.6604890 (2009). 10.1038/sj.bjc.6604890

[25]

Severi, G. et al. Asthma, asthma medications, and prostate cancer risk. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 19, 2318–2324, doi: 10.1158/1055-9965.EPI-10-0381 (2010). 10.1158/1055-9965.epi-10-0381

[26]

Su, Y. L., Chou, C. L., Rau, K. M. & Lee, C. T. Asthma and Risk of Prostate Cancer: A Population-Based Case-Cohort Study in Taiwan. Medicine 94, e1371, doi: 10.1097/MD.0000000000001371 (2015). 10.1097/md.0000000000001371

[27]

El-Zein, M. et al. History of asthma or eczema and cancer risk among men: a population-based case-control study in Montreal, Quebec, Canada. Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology 104, 378–384, doi: 10.1016/j.anai.2010.03.003 (2010). 10.1016/j.anai.2010.03.003

[28]

Platz, E. A. et al. Asthma and risk of lethal prostate cancer in the Health Professionals Follow-Up Study. International journal of cancer. Journal international du cancer 137, 949–958, doi: 10.1002/ijc.29463 (2015). 10.1002/ijc.29463

[29]

Skaaby, T., Nystrup Husemoen, L. L., Roswall, N., Thuesen, B. H. & Linneberg, A. Atopy and development of cancer: a population-based prospective study. The journal of allergy and clinical immunology. In practice 2, 779–785, doi: 10.1016/j.jaip.2014.06.010 (2014). 10.1016/j.jaip.2014.06.010

[30]

Taghizadeh, N. et al. Objective allergy markers and risk of cancer mortality and hospitalization in a large population-based cohort. Cancer causes & control: CCC 26, 99–109, doi: 10.1007/s10552-014-0489-9 (2015). 10.1007/s10552-014-0489-9

[31]

Weiss, D. et al. Asthma, allergy and the risk of prostate cancer: results from the Montreal PROtEuS study. Cancer epidemiology 38, 695–699, doi: 10.1016/j.canep.2014.10.003 (2014). 10.1016/j.canep.2014.10.003

[32]

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

D. Moher, A. Liberati, J. Tetzlaff et al.

BMJ 2009 10.1136/bmj.b2535

[33]

Josephs, D. H., Spicer, J. F., Corrigan, C. J., Gould, H. J. & Karagiannis, S. N. Epidemiological associations of allergy, IgE and cancer. Clinical and Experimental Allergy 43, 1110–1123 (2013). 10.1111/cea.12178

[34]

Turner, M. C., Chen, Y., Krewski, D. & Ghadirian, P. An overview of the association between allergy and cancer. International journal of cancer. Journal international du cancer 118, 3124–3132, doi: 10.1002/ijc.21752 (2006). 10.1002/ijc.21752

[35]

Wang, H. & Diepgen, T. L. Is atopy a protective or a risk factor for cancer? A review of epidemiological studies. Allergy 60, 1098–1111, doi: 10.1111/j.1398-9995.2005.00813.x (2005). 10.1111/j.1398-9995.2005.00813.x

[36]

Merrill, R. M., Isakson, R. T. & Beck, R. E. The association between allergies and cancer: what is currently known? Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology 99, 102–116; quiz 117-109, 150, doi: 10.1016/S1081-1206(10)60632-1 (2007). 10.1016/s1081-1206(10)60632-1

[37]

Josephs, D. H., Spicer, J. F., Corrigan, C. J., Gould, H. J. & Karagiannis, S. N. Epidemiological associations of allergy, IgE and cancer. Clinical and experimental allergy: journal of the British Society for Allergy and Clinical Immunology 43, 1110–1123, doi: 10.1111/cea.12178 (2013). 10.1111/cea.12178

[38]

Sherman, P. W., Holland, E. & Sherman, J. S. Allergies: their role in cancer prevention. The Quarterly review of biology 83, 339–362 (2008). 10.1086/592850

[39]

Olson, S. H. et al. Serum immunoglobulin e and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 23, 1414–1420, doi: 10.1158/1055-9965.EPI-13-1359 (2014). 10.1158/1055-9965.epi-13-1359

[40]

Sumino, K. et al. Coexisting chronic conditions associated with mortality and morbidity in adult patients with asthma. The Journal of asthma: official journal of the Association for the Care of Asthma 51, 306–314, doi: 10.3109/02770903.2013.879881 (2014). 10.3109/02770903.2013.879881

[41]

Alderson, M. Mortality from malignant disease in patients with asthma. Lancet (London, England) 2, 1475–1477 (1974). 10.1016/s0140-6736(74)90217-7

[42]

Vandentorren, S. et al. Long-term mortality among adults with or without asthma in the PAARC study. The European respiratory journal 21, 462–467 (2003). 10.1183/09031936.03.00030303

[43]

Lindelof, B., Granath, F., Tengvall-Linder, M. & Ekbom, A. Allergy and cancer. Allergy 60, 1116–1120, doi: 10.1111/j.1398-9995.2005.00808.x (2005). 10.1111/j.1398-9995.2005.00808.x

[44]

Markowe, H. L. et al. Prognosis in adult asthma: a national study. Br Med J (Clin Res Ed) 295, 949–952 (1987). 10.1136/bmj.295.6604.949

[45]

Petroianu, A., Chaves, D. N. & De Oliveira, O. Jr. Comparative incidence of allergy in the presence or absence of cancer. The Journal of international medical research 23, 358–363 (1995). 10.1177/030006059502300505

[46]

Petridou, E. T. et al. Breast cancer risk in relation to most prevalent IgE specific antibodies: a case control study in Greece. Anticancer research 27, 1709–1713 (2007).

[47]

Zhou, M. H. & Yang, Q. M. Association of asthma with the risk of acute leukemia and non-Hodgkin lymphoma. Molecular and clinical oncology 3, 859–864, doi: 10.3892/mco.2015.561 (2015). 10.3892/mco.2015.561

[48]

Pardoll, D. Does the immune system see tumors as foreign or self? Annual review of immunology 21, 807–839, doi: 10.1146/annurev.immunol.21.120601.141135 (2003). 10.1146/annurev.immunol.21.120601.141135

[49]

Lu, H., Ouyang, W. & Huang, C. Inflammation, a key event in cancer development. Molecular cancer research: MCR 4, 221–233, doi: 10.1158/1541-7786.MCR-05-0261 (2006). 10.1158/1541-7786.mcr-05-0261

[50]

Hartling, L. et al. Testing the Newcastle Ottawa Scale showed low reliability between individual reviewers. Journal of clinical epidemiology 66, 982–993, doi: 10.1016/j.jclinepi.2013.03.003 (2013). 10.1016/j.jclinepi.2013.03.003

Showing 50 of 55 references

Metrics

12

Citations

55

References

Details

Published: Oct 21, 2016
Vol/Issue: 6(1)
License: View

Authors

School of Physics and Electronics; Institute of Super-microstructure and Ultrafast Process in Advanced Materials; Central South University; Changsha; China

1Department of Botany and Plant Sciences, University of California, Riverside, California.; 2Graduate Program in Genetics, Genomics, and Bioinformatics, University of California, Riverside, California.

Hebei Agricultural University

Cite This Article

Jianguo Zhu, Jukun Song, Zezhen Liu, et al. (2016). Association between allergic conditions and risk of prostate cancer: A Prisma-Compliant Systematic Review and Meta-Analysis. Scientific Reports, 6(1). https://doi.org/10.1038/srep35682

Association between allergic conditions and risk of prostate cancer: A Prisma-Compliant Systematic Review and Meta-Analysis

You May Also Like