Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues

Anna Marsano; Chiara Conficconi; Marta Lemme; Paola Occhetta; Emanuele Gaudiello; Emiliano Votta; Giulia Cerino; Alberto Redaelli; Marco Rasponi

doi:10.1039/c5lc01356a

journal article Jan 01, 2016

Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues

Anna Marsano

Chiara Conficconi Marta Lemme Paola Occhetta

Emanuele Gaudiello Emiliano Votta

Giulia Cerino Alberto Redaelli

Marco Rasponi

Lab on a Chip Vol. 16 No. 3 pp. 599-610 · Royal Society of Chemistry (RSC)

View at Publisher Save 10.1039/c5lc01356a

Abstract

The beating heart-on-a-chip (i) generates 3D cardiac constructs with well-defined geometries from cell-laden hydrogel prepolymers, (ii) provides uniaxial cyclic mechanical stimulation, (iii) allows efficient delivery of drugs and chemicals.

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396

Citations

38

References

Details

Published: Jan 01, 2016
Vol/Issue: 16(3)
Pages: 599-610

Authors

A

Anna Marsano