Micro-Raman spectroscopic analysis of liquid–liquid phase separation

Suin Choi; So Yeon Chun; Kyungwon Kwak; Minhaeng Cho

doi:10.1039/d2cp05115j

journal article Jan 01, 2023

Micro-Raman spectroscopic analysis of liquid–liquid phase separation

Suin Choi

So Yeon Chun Kyungwon Kwak

Minhaeng Cho

Physical Chemistry Chemical Physics Vol. 25 No. 13 pp. 9051-9060 · Royal Society of Chemistry (RSC)

View at Publisher Save 10.1039/d2cp05115j

Abstract

This study aims to understand the molecular mechanism of liquid–liquid phase separation (LLPS) in a heteroprotein system using micro-Raman spectroscopy. We observed specific structural information about proteins and water inside/outside a droplet.

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References

Details

Published: Jan 01, 2023
Vol/Issue: 25(13)
Pages: 9051-9060
License: View

Authors

S

Suin Choi

Center for Molecular Spectroscopy and Dynamics, Institute for Basic Science (IBS), Seoul 02841, Republic of Korea; Department of Chemistry, Korea University, Seoul 02841, Republic of Korea

S

So Yeon Chun

Center for Molecular Spectroscopy and Dynamics, Institute for Basic Science (IBS), Seoul 02841, Republic of Korea; Department of Chemistry, Korea University, Seoul 02841, Republic of Korea

K

Kyungwon Kwak

Center for Molecular Spectroscopy and Dynamics, Institute for Basic Science (IBS), Seoul 02841, Republic of Korea; Department of Chemistry, Korea University, Seoul 02841, Republic of Korea

M

Minhaeng Cho

Center for Molecular Spectroscopy and Dynamics, Institute for Basic Science (IBS), Seoul 02841, Republic of Korea; Department of Chemistry, Korea University, Seoul 02841, Republic of Korea

Funding

National Research Foundation of Korea Award: NRF-2020R1A2C2010675

Institute for Basic Science Award: IBS-R023-D1

Cite This Article

Suin Choi, So Yeon Chun, Kyungwon Kwak, et al. (2023). Micro-Raman spectroscopic analysis of liquid–liquid phase separation. Physical Chemistry Chemical Physics, 25(13), 9051-9060. https://doi.org/10.1039/d2cp05115j

Micro-Raman spectroscopic analysis of liquid–liquid phase separation

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