Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies

Marco Bertolini; Man Sing Wong; Lorena Mendive-Tapia; Marc Vendrell

doi:10.1039/d2cs00928e

journal article Open Access Jan 01, 2023

Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies

Marco Bertolini

Man Sing Wong

Lorena Mendive-Tapia Marc Vendrell

Chemical Society Reviews Vol. 52 No. 16 pp. 5352-5372 · Royal Society of Chemistry (RSC)

View at Publisher Save 10.1039/d2cs00928e

Abstract

T cells are an essential component of the immune system and display multiple biological functions. Smart probes range from small fluorophores to nanoconstructs, and can target metabolic and enzymatic biomarkers as well as cell-surface receptors.

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Citations

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References

Details

Published: Jan 01, 2023
Vol/Issue: 52(16)
Pages: 5352-5372
License: View

Authors

M

Marco Bertolini

Centre for Inflammation Research, The University of Edinburgh, EH16 4UU, Edinburgh, UK; IRR Chemistry Hub, Institute for Regeneration and Repair, The University of Edinburgh, EH16 4UU, Edinburgh, UK

M

Man Sing Wong

Centre for Inflammation Research, The University of Edinburgh, EH16 4UU, Edinburgh, UK; IRR Chemistry Hub, Institute for Regeneration and Repair, The University of Edinburgh, EH16 4UU, Edinburgh, UK

L

Lorena Mendive-Tapia

Centre for Inflammation Research, The University of Edinburgh, EH16 4UU, Edinburgh, UK; IRR Chemistry Hub, Institute for Regeneration and Repair, The University of Edinburgh, EH16 4UU, Edinburgh, UK

M

Marc Vendrell

Centre for Inflammation Research, The University of Edinburgh, EH16 4UU, Edinburgh, UK; IRR Chemistry Hub, Institute for Regeneration and Repair, The University of Edinburgh, EH16 4UU, Edinburgh, UK

Funding

H2020 European Research Council Award: 771443

H2020 Marie Skłodowska-Curie Actions Award: 956477

Medical Research Scotland Award: 50266-2020

Cite This Article

Marco Bertolini, Man Sing Wong, Lorena Mendive-Tapia, et al. (2023). Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies. Chemical Society Reviews, 52(16), 5352-5372. https://doi.org/10.1039/d2cs00928e

Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies

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