Prospects of nanoparticle-based radioenhancement for radiotherapy

Lukas R. H. Gerken; Maren E. Gerdes; Martin Pruschy; Inge K. Herrmann

doi:10.1039/d3mh00265a

journal article Open Access Jan 01, 2023

Prospects of nanoparticle-based radioenhancement for radiotherapy

Lukas R. H. Gerken Maren E. Gerdes Martin Pruschy

Inge K. Herrmann

Materials Horizons Vol. 10 No. 10 pp. 4059-4082 · Royal Society of Chemistry (RSC)

View at Publisher Save 10.1039/d3mh00265a

Abstract

Inorganic nanomaterials show promising potential for radiotherapy enhancement. This article provides a concise summary of mechanisms involved, materials designs and future prospects of nanoparticle-based radioenhancement for precision medicine.

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References

276

[1]

The use of gold nanoparticles to enhance radiotherapy in mice

James F Hainfeld, Daniel N Slatkin, Henry M Smilowitz

Physics in Medicine and Biology 2004 10.1088/0031-9155/49/18/n03

[2]

Verry Radiother. Oncol. (2021) 10.1016/j.radonc.2021.04.021

[3]

Anselmo Bioeng. Transl. Med. (2019) 10.1002/btm2.10143

[4]

Bonvalot Clin. Cancer Res. (2017) 10.1158/1078-0432.ccr-16-1297

[5]

Lu Nat. Biomed. Eng. (2018) 10.1038/s41551-018-0203-4

[6]

Neufeld Chem. – Eur. J. (2021) 10.1002/chem.202003523

[7]

Ricketts Br. J. Radiol. (2018) 10.1259/bjr.20180325

[8]

Penninckx Cancers (2020) 10.3390/cancers12082021

[9]

I.Obodovskiy , in Fundamentals of Radiation and Chemical Safety , ed. I. Obodovskiy , Elsevier , Amsterdam , 2015 , pp. 87–131 10.1016/b978-0-12-802026-5.00004-1

[10]

J. E.Turner , Atoms, Radiation, and Radiation Protection , Wiley-VCH , Weinheim , 2007 10.1002/9783527616978

[11]

Penet Front. Oncol. (2021) 10.3389/fonc.2020.599204

[12]

Ramos-Méndez Phys. Med. Biol. (2018) 10.1088/1361-6560/aac04c

[13]

Kreipl Radiat. Environ. Biophys. (2008) 10.1007/s00411-008-0194-8

[14]

Lai Phys. Med. Biol. (2021) 10.1088/1361-6560/abc93b

[15]

Aykin-Burns Rare (2010) 10.1667/rr2220.1

[16]

Wang Mil. Med. Res. (2018)

[17]

Hirayama Rare (2009) 10.1667/rr1490.1

[18]

Ito Rare (2006) 10.1667/rr3557.1

[19]

Hirayama Radiat. Res. (2013) 10.1667/rr13368.1

[20]

Shinohara Acta Oncol. (1996) 10.3109/02841869609104039

[21]

Grimes Biomed. Phys. Eng. Express (2015) 10.1088/2057-1976/1/4/045209

[22]

Harrington Clin. Oncol. (2007) 10.1016/j.clon.2007.04.009

[23]

Boustani Cancers (2019) 10.3390/cancers11060860

[24]

Marill Radiat. Oncol. (2014) 10.1186/1748-717x-9-150

[25]

Kuncic Phys. Med. Biol. (2018) 10.1088/1361-6560/aa99ce

[26]

Li Phys. Med. (2020) 10.1016/j.ejmp.2019.12.011

[27]

Incerti Nucl. Instrum. Methods Phys. Res., Sect. B (2016) 10.1016/j.nimb.2016.02.005

[28]

Physical basis and biological mechanisms of gold nanoparticle radiosensitization

Karl T. Butterworth, Stephen J. McMahon, Fred J. Currell et al.

Nanoscale 2012 10.1039/c2nr31227a

[29]

Rudek Phys. Med. Biol. (2019) 10.1088/1361-6560/ab314c

[30]

Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy

Stephen J. McMahon, Wendy B. Hyland, Mark F. Muir et al.

Radiotherapy and Oncology 2011 10.1016/j.radonc.2011.08.026

[31]

Fuss Phys. Med. Biol. (2020) 10.1088/1361-6560/ab7504

[32]

Lin Phys. Med. Biol. (2014) 10.1088/0031-9155/59/24/7675

[33]

Aliru Int. J. Radiat. Oncol., Biol., Phys. (2017) 10.1016/j.ijrobp.2017.06.1983

[34]

Özçelik Nanotechnology (2020) 10.1088/1361-6528/aba02b

[35]

Li Chem. Sci. (2018) 10.1039/c7sc04458e

[36]

Deng ACS Cent. Sci. (2020) 10.1021/acscentsci.9b01121

[37]

McMahon J. Phys.: Conf. Ser. (2017)

[38]

Peukert Med. Phys. (2020) 10.1002/mp.13923

[39]

Jones Clin. Oncol. (2018) 10.1016/j.clon.2018.01.010

[40]

Schlathölter Int. J. Nanomed. (2016) 10.2147/ijn.s99410

[41]

Basics of particle therapy I: physics

Seo Hyun Park, Jin Oh Kang

Radiation Oncology Journal 2011 10.3857/roj.2011.29.3.135

[42]

Kim Nanotechnology (2010) 10.1088/0957-4484/21/42/425102

[43]

Enhanced proton treatment in mouse tumors through proton irradiated nanoradiator effects on metallic nanoparticles

Jong-Ki Kim, Seung-Jun Seo, Hong-Tae Kim et al.

Physics in Medicine and Biology 2012 10.1088/0031-9155/57/24/8309

[44]

Polf Appl. Phys. Lett. (2011) 10.1063/1.3589914

[45]

Cunningham Front. Public Health (2021) 10.3389/fpubh.2021.699822

[46]

Cho Phys. Med. Biol. (2016) 10.1088/0031-9155/61/6/2562

[47]

Wälzlein Phys. Med. Biol. (2014) 10.1088/0031-9155/59/6/1441

[48]

Heuskin Med. Phys. (2017) 10.1002/mp.12362

[49]

Ku EJNMMI Radiopharm. Chem. (2019) 10.1186/s41181-019-0075-2

[50]

Sotiropoulos Nanoscale (2017) 10.1039/c7nr07310k

Showing 50 of 276 references

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Details

Published: Jan 01, 2023
Vol/Issue: 10(10)
Pages: 4059-4082
License: View

Authors

L

Lukas R. H. Gerken

Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland; Particles-Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland

M

Maren E. Gerdes

Karolinska Institutet, Solnavägen 1, 171 77 Stockholm, Sweden

M

Martin Pruschy

Laboratory for Applied Radiobiology, Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland

I

Inge K. Herrmann

Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland; Particles-Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung Award: 181290

ETH Zürich Foundation Award: ETH-07 21-2

Swiss Cancer Research Foundation Award: KFS-4868-08-2019

Cite This Article

Lukas R. H. Gerken, Maren E. Gerdes, Martin Pruschy, et al. (2023). Prospects of nanoparticle-based radioenhancement for radiotherapy. Materials Horizons, 10(10), 4059-4082. https://doi.org/10.1039/d3mh00265a

Prospects of nanoparticle-based radioenhancement for radiotherapy

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