journal article Dec 01, 2020

Insights on drying and precipitation dynamics of respiratory droplets from the perspective of COVID-19

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Abstract
We isolate a nano-colloidal droplet of surrogate mucosalivary fluid to gain fundamental insights into airborne nuclei’s infectivity and viral load distribution during the COVID-19 pandemic. The salt-water solution containing particles at reported viral loads is acoustically trapped in a contactless environment to emulate the drying, flow, and precipitation dynamics of real airborne droplets. Similar experiments validate observations with the surrogate fluid with samples of human saliva samples from a healthy subject. A unique feature emerges regarding the final crystallite dimension; it is always 20%–30% of the initial droplet diameter for different sizes and ambient conditions. Airborne-precipitates nearly enclose the viral load within its bulk while the substrate precipitates exhibit a high percentage (∼80–90%) of exposed virions (depending on the surface). This work demonstrates the leveraging of an inert nano-colloidal system to gain insights into an equivalent biological system.
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Published
Dec 01, 2020
Vol/Issue
32(12)
Cite This Article
Shouvik Basu, Prasenjit Kabi, Swetaprovo Chaudhuri, et al. (2020). Insights on drying and precipitation dynamics of respiratory droplets from the perspective of COVID-19. Physics of Fluids, 32(12). https://doi.org/10.1063/5.0037360
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